{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T02:09:51Z","timestamp":1782439791774,"version":"3.54.5"},"reference-count":20,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2011,11,1]],"date-time":"2011-11-01T00:00:00Z","timestamp":1320105600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Scott Med J"],"published-print":{"date-parts":[[2011,11]]},"abstract":"<jats:p> Our aim was to explore the clinical application value of high-intensity focused ultrasound (HIFU) therapy for tubal pregnancy. Forty hospitalized patients with tubal pregnancies (28 cases of non-ruptured tubal pregnancy and 12 cases of ruptured tubal pregnancy) were selected to receive HIFU therapy. Serum human chorionic gonadotropin (\u03b2-HCG) concentrations were compared before and after treatment. Serum \u03b2-HCG was measured weekly and patients received observation only if the concentration decreased by 15% or more, compared with the previous value. Patients were given supplement HIFU therapy if the decrease in the serum \u03b2-HCG was &lt;15% within two weeks. Ultrasound was used to detect the volume changes in the ectopic lesions before and after treatment, and changes in vital signs and complications were recorded. Contrast-enhanced ultrasonography was used to assess fallopian tube patency after treatment. HIFU treatment was successful in 33 of the 40 patients (82%). Seven patients failed HIFU treatment and received surgical therapy (18%). Before and after treatment, serum \u03b2-HCG concentrations and lesion volume were significantly different ( P &lt; 0.05, P &lt; 0.01, respectively). Post-treatment tubal contrast-enhanced ultrasonography showed tubal patency on the affected side in 21 cases (64%) at six months and in 27 cases (82%) at 12 months. In conclusion, HIFU is safe and effective, and can be a treatment option for tubal pregnancy. <\/jats:p>","DOI":"10.1258\/smj.2011.011161","type":"journal-article","created":{"date-parts":[[2011,11,17]],"date-time":"2011-11-17T09:01:13Z","timestamp":1321520473000},"page":"214-219","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["A preliminary clinical study on high-intensity focused ultrasound therapy for tubal pregnancy"],"prefix":"10.1177","volume":"56","author":[{"given":"G-B","family":"He","sequence":"first","affiliation":[{"name":"Department of Ultrasonography, Xijing Hospital, The Fourth Military Medical University, Xi'an 710032, Shaanxi Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W","family":"Luo","sequence":"additional","affiliation":[{"name":"Department of Ultrasonography, Xijing Hospital, The Fourth Military Medical University, Xi'an 710032, Shaanxi Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"X-D","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Ultrasonography, Xijing Hospital, The Fourth Military Medical University, Xi'an 710032, Shaanxi Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L-W","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Ultrasonography, Xijing Hospital, The Fourth Military Medical University, Xi'an 710032, Shaanxi Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Ultrasonography, Xijing Hospital, The Fourth Military Medical University, Xi'an 710032, Shaanxi Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"X-D","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Xijing Hospital, The Fourth Military Medical University, Xi'an 710032, Shaanxi Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2011,11,16]]},"reference":[{"key":"bibr1-smj.2011.011161","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinimag.2008.02.027"},{"key":"bibr2-smj.2011.011161","doi-asserted-by":"publisher","DOI":"10.1097\/00001703-200010000-00005"},{"key":"bibr3-smj.2011.011161","first-page":"1406","author":"Varma R","year":"2009","journal-title":"Clin Evid (Online)"},{"key":"bibr4-smj.2011.011161","doi-asserted-by":"publisher","DOI":"10.1016\/S1701-2163(16)34055-5"},{"key":"bibr5-smj.2011.011161","doi-asserted-by":"publisher","DOI":"10.1053\/j.sult.2008.01.001"},{"key":"bibr6-smj.2011.011161","doi-asserted-by":"publisher","DOI":"10.1016\/j.pbiomolbio.2006.07.005"},{"key":"bibr7-smj.2011.011161","doi-asserted-by":"publisher","DOI":"10.1080\/02656730601185924"},{"key":"bibr8-smj.2011.011161","doi-asserted-by":"publisher","DOI":"10.1097\/01.ruq.0000237259.25885.72"},{"key":"bibr9-smj.2011.011161","doi-asserted-by":"publisher","DOI":"10.1038\/nrc1591"},{"key":"bibr10-smj.2011.011161","doi-asserted-by":"publisher","DOI":"10.1080\/13645700500470124"},{"key":"bibr11-smj.2011.011161","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.07.2671"},{"key":"bibr12-smj.2011.011161","doi-asserted-by":"publisher","DOI":"10.7863\/jum.2009.28.1.100"},{"key":"bibr13-smj.2011.011161","doi-asserted-by":"publisher","DOI":"10.1111\/j.1479-828X.2009.01032.x"},{"key":"bibr14-smj.2011.011161","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2009.03.015"},{"key":"bibr15-smj.2011.011161","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2008.08.049"},{"key":"bibr16-smj.2011.011161","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp0810384"},{"key":"bibr17-smj.2011.011161","unstructured":"Chen WS, Lafon C, Matula TJ.,  Mechanisms of Lesion Formation in High Intensity Focused Ultrasound Therapy. 2nd International Symposium on Therapeutic Ultrasound. Seattle, Washington, USA, 29 July-2 August 2002: 30"},{"key":"bibr18-smj.2011.011161","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-3944(02)00004-4"},{"key":"bibr19-smj.2011.011161","doi-asserted-by":"publisher","DOI":"10.1002\/uog.1983"},{"key":"bibr20-smj.2011.011161","doi-asserted-by":"publisher","DOI":"10.1067\/S0002-9378(03)00664-1"}],"container-title":["Scottish Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/smj.2011.011161","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1258\/smj.2011.011161","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/smj.2011.011161","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,3]],"date-time":"2025-03-03T08:37:51Z","timestamp":1740991071000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1258\/smj.2011.011161"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,11]]},"references-count":20,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2011,11]]}},"alternative-id":["10.1258\/smj.2011.011161"],"URL":"https:\/\/doi.org\/10.1258\/smj.2011.011161","relation":{},"ISSN":["0036-9330","2045-6441"],"issn-type":[{"value":"0036-9330","type":"print"},{"value":"2045-6441","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,11]]}}}