{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,3]],"date-time":"2025-03-03T05:38:56Z","timestamp":1740980336835,"version":"3.38.0"},"reference-count":21,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2011,12,22]],"date-time":"2011-12-22T00:00:00Z","timestamp":1324512000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Scott Med J"],"published-print":{"date-parts":[[2012,2]]},"abstract":"<jats:p> To our knowledge there are no reports of a primary multifocal spindle cell sarcoma affecting both long bones of the lower limb in an elderly patient. An 83-year-old man presented with a progressively painful right ankle, without a history of trauma. Radiographs demonstrated a pathological fracture through a mixed lytic and sclerotic lesion in the distal tibia. Staging investigations, including bone scintigraphy and magnetic resonance imaging, revealed a second lytic lesion in the right distal femur. A provisional diagnosis of metastatic disease was favoured and intramedullary nailing was considered. However, computed tomography of the chest, abdomen and pelvis, and relevant blood tests revealed no evidence of a primary malignancy. Open biopsy of the tibial lesion showed high-grade pleomorphic spindle cells consistent with a primary bone sarcoma. The patient was treated successfully with a right trans-femoral amputation. In conclusion, we recommend early bone biopsy to allow accurate diagnosis and appropriate skeletal management in elderly patients. <\/jats:p>","DOI":"10.1258\/smj.2011.011279","type":"journal-article","created":{"date-parts":[[2011,12,23]],"date-time":"2011-12-23T04:39:44Z","timestamp":1324615184000},"page":"1-4","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Multifocal Primary Bone Sarcoma in the Elderly: A Rare Case and Review of the Literature"],"prefix":"10.1177","volume":"57","author":[{"given":"A D","family":"Duckworth","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery, 51 Little France Crescent, Edinburgh EH16 4SU, Scotland, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I","family":"Beggs","sequence":"additional","affiliation":[{"name":"Department of Radiology, 51 Little France Crescent, Edinburgh EH16 4SU, Scotland, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D M","family":"Salter","sequence":"additional","affiliation":[{"name":"Department of Pathology, New Royal Infirmary, 51 Little France Crescent, Edinburgh EH16 4SU, Scotland, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J T","family":"Patton","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, 51 Little France Crescent, Edinburgh EH16 4SU, Scotland, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D E","family":"Porter","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, 51 Little France Crescent, Edinburgh EH16 4SU, Scotland, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2011,12,22]]},"reference":[{"unstructured":"Peake D, Grimer RJ, Spooner D.,  Primary spindle call sarcoma of bone - an assessment of outcome. CTOS 10th Annual Meeting, 2004: 11","key":"bibr1-smj.2011.011279"},{"key":"bibr2-smj.2011.011279","first-page":"673","volume":"57","author":"Weber K","year":"2008","journal-title":"Instr Course Lect"},{"doi-asserted-by":"publisher","key":"bibr3-smj.2011.011279","DOI":"10.1259\/0007-1285-54-647-932"},{"doi-asserted-by":"publisher","key":"bibr4-smj.2011.011279","DOI":"10.1016\/S0046-8177(79)80072-6"},{"doi-asserted-by":"publisher","key":"bibr5-smj.2011.011279","DOI":"10.1186\/1750-1172-2-6"},{"doi-asserted-by":"publisher","key":"bibr6-smj.2011.011279","DOI":"10.1080\/02841850600812736"},{"issue":"12","key":"bibr7-smj.2011.011279","first-page":"S12","volume":"6","author":"Patton JT","year":"2002","journal-title":"Sarcoma"},{"doi-asserted-by":"publisher","key":"bibr8-smj.2011.011279","DOI":"10.1097\/01.rlu.0000102743.49568.1d"},{"doi-asserted-by":"publisher","key":"bibr9-smj.2011.011279","DOI":"10.1302\/0301-620X.81B1.9514"},{"doi-asserted-by":"publisher","key":"bibr10-smj.2011.011279","DOI":"10.4065\/82.11.1409"},{"doi-asserted-by":"publisher","key":"bibr11-smj.2011.011279","DOI":"10.1097\/01.rlu.0000178027.20780.95"},{"doi-asserted-by":"publisher","key":"bibr12-smj.2011.011279","DOI":"10.1007\/s11999-008-0546-3"},{"doi-asserted-by":"publisher","key":"bibr13-smj.2011.011279","DOI":"10.1200\/JCO.1999.17.10.3260"},{"doi-asserted-by":"publisher","key":"bibr14-smj.2011.011279","DOI":"10.1302\/0301-620X.89B9.19255"},{"doi-asserted-by":"publisher","key":"bibr15-smj.2011.011279","DOI":"10.1016\/j.ejca.2004.08.026"},{"doi-asserted-by":"publisher","key":"bibr16-smj.2011.011279","DOI":"10.1586\/14737140.6.2.239"},{"doi-asserted-by":"publisher","key":"bibr17-smj.2011.011279","DOI":"10.2106\/00004623-200201000-00008"},{"doi-asserted-by":"publisher","key":"bibr18-smj.2011.011279","DOI":"10.1016\/j.ejca.2007.07.004"},{"doi-asserted-by":"publisher","key":"bibr19-smj.2011.011279","DOI":"10.1155\/2008\/402378"},{"doi-asserted-by":"publisher","key":"bibr20-smj.2011.011279","DOI":"10.1200\/JCO.2007.14.9104"},{"doi-asserted-by":"publisher","key":"bibr21-smj.2011.011279","DOI":"10.3346\/jkms.2006.21.4.715"}],"container-title":["Scottish Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/smj.2011.011279","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1258\/smj.2011.011279","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/smj.2011.011279","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,2]],"date-time":"2025-03-02T12:20:23Z","timestamp":1740918023000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1258\/smj.2011.011279"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,12,22]]},"references-count":21,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,2]]}},"alternative-id":["10.1258\/smj.2011.011279"],"URL":"https:\/\/doi.org\/10.1258\/smj.2011.011279","relation":{},"ISSN":["0036-9330","2045-6441"],"issn-type":[{"type":"print","value":"0036-9330"},{"type":"electronic","value":"2045-6441"}],"subject":[],"published":{"date-parts":[[2011,12,22]]}}}