{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,4]],"date-time":"2025-03-04T05:19:59Z","timestamp":1741065599720,"version":"3.38.0"},"reference-count":8,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2008,7,1]],"date-time":"2008-07-01T00:00:00Z","timestamp":1214870400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Trop Doct"],"published-print":{"date-parts":[[2008,7]]},"abstract":"<jats:p> In a retrospective study of 1415 patients aged 15 and over, we determined the incidence of clinically important hyponatraemia and hypokalaemia in adults with uncomplicated malaria. On admission, serum concentrations of sodium (135\u2013145 mmol\/L) and potassium (3.5\u20135.0 mmol\/L) were found outside these reference ranges in 81% of patients. Severe hypokalaemia (K+ &lt;3.0 mmol\/L) and severe hyponatraemia (Na+ &lt;125 mmol\/L occurred in 4.4% and 0.6% of the patients, respectively. For hypokalaemia (43%) and hyponatraemia (37%), hypovolaemia, blood urea to creatinine ratio and high serum glucose (&gt;100 mg\/dL) were all independent factors ( P &lt; 0.001). Other independent predictors for hypokalaemia were Plasmodium vivax infection, female gender; and for hyponatraemia, P. falciparum infection, male gender, concentrations of G-6-PD and serum bicarbonate. <\/jats:p>","DOI":"10.1258\/td.2007.070112","type":"journal-article","created":{"date-parts":[[2008,7,15]],"date-time":"2008-07-15T19:48:30Z","timestamp":1216151310000},"page":"155-157","source":"Crossref","is-referenced-by-count":5,"title":["Hyponatraemia and hypokalaemia in adults with uncomplicated malaria in Thailand"],"prefix":"10.1177","volume":"38","author":[{"given":"Vipa","family":"Thanachartwet","sequence":"first","affiliation":[{"name":"Department of Clinical Tropical Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Srivicha","family":"Krudsood","sequence":"additional","affiliation":[{"name":"Department of Tropical Hygiene, Faculty of Tropical Medicine, Mahidol University, 420\/6 Rajvithee Road, Ratchathevee, Bangkok 10400, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noppadon","family":"Tangpukdee","sequence":"additional","affiliation":[{"name":"Department of Clinical Tropical Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weerapong","family":"Phumratanaprapin","sequence":"additional","affiliation":[{"name":"Department of Clinical Tropical Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Udomsak","family":"Silachamroon","sequence":"additional","affiliation":[{"name":"Department of Clinical Tropical Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wattana","family":"Leowattana","sequence":"additional","affiliation":[{"name":"Department of Clinical Tropical Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Polrat","family":"Wilairatana","sequence":"additional","affiliation":[{"name":"Department of Clinical Tropical Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gary M","family":"Brittenham","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Medicine, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sornchai","family":"Looareesuwan","sequence":"additional","affiliation":[{"name":"Department of Clinical Tropical Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guy H","family":"Neild","sequence":"additional","affiliation":[{"name":"Institute of Urology and Nephrology, University College London, London, NW1 2BU, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2008,7,1]]},"reference":[{"key":"bibr-TD-07-0112C1","unstructured":"World Health Organization. Guidelines for the Treatment of Malaria. Switzerland, 2006:5\u20136"},{"key":"bibr-TD-07-0112C2","first-page":"836","volume-title":"Clinical Physiology of Acid\u2013Base and Electrolyte Disorders","author":"Rose BD","year":"2001"},{"key":"bibr-TD-07-0112C3","first-page":"696","volume-title":"Clinical Physiology of Acid\u2013Base and Electrolyte Disorders","author":"Rose BD","year":"2001"},{"key":"bibr-TD-07-0112C4","doi-asserted-by":"publisher","DOI":"10.1086\/426022"},{"key":"bibr-TD-07-0112C5","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1994.50.602"},{"key":"bibr-TD-07-0112C6","doi-asserted-by":"publisher","DOI":"10.1136\/adc.74.3.201"},{"key":"bibr-TD-07-0112C7","first-page":"47","volume":"25","author":"Sowunmi A","year":"1996","journal-title":"Afr J Med Med Sci"},{"key":"bibr-TD-07-0112C8","doi-asserted-by":"publisher","DOI":"10.1159\/000169042"}],"container-title":["Tropical Doctor"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/td.2007.070112","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1258\/td.2007.070112","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/td.2007.070112","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,3]],"date-time":"2025-03-03T05:37:29Z","timestamp":1740980249000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1258\/td.2007.070112"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,7]]},"references-count":8,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2008,7]]}},"alternative-id":["10.1258\/td.2007.070112"],"URL":"https:\/\/doi.org\/10.1258\/td.2007.070112","relation":{},"ISSN":["0049-4755","1758-1133"],"issn-type":[{"type":"print","value":"0049-4755"},{"type":"electronic","value":"1758-1133"}],"subject":[],"published":{"date-parts":[[2008,7]]}}}