{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T00:31:46Z","timestamp":1789605106874,"version":"build-2803163510"},"reference-count":10,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2008,10,1]],"date-time":"2008-10-01T00:00:00Z","timestamp":1222819200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Trop Doct"],"published-print":{"date-parts":[[2008,10]]},"abstract":"<jats:p> We report on the clinico-haematological profile of pancytopenia in children from the Departments of Pediatrics and Pathology, Institute of Medical Sciences, Banaras Hindu University, India, over a period of 30 months. Pancytopenia was defined as: haemoglobin &lt;10 g\/dL, absolute neutrophil count 1.5 \u00d7 10<jats:sup>9<\/jats:sup>\/L and platelet count &lt;100 \u00d7 10<jats:sup>9<\/jats:sup>\/L. A detailed history, clinical examination and haematological parameters were recorded. Bone marrow aspiration and trephine biopsy were carried out in all cases. One hundred and five cases aged 1.5\u201318 years, with a mean age of 8.6 years, were included in the study. Aplastic anaemia was the most common cause of pancytopenia (43%) followed by acute leukaemia (25%). Infections were the third most common cause of pancytopenia of which kala azar was the most common. Megaloblastic anaemia was seen in 6.7%. <\/jats:p>","DOI":"10.1258\/td.2008.070422","type":"journal-article","created":{"date-parts":[[2008,9,26]],"date-time":"2008-09-26T21:24:03Z","timestamp":1222464243000},"page":"241-243","source":"Crossref","is-referenced-by-count":24,"title":["A study of clinico-haematological profiles of pancytopenia in children"],"prefix":"10.1177","volume":"38","author":[{"given":"V","family":"Gupta","sequence":"first","affiliation":[{"name":"Department of Pediatrics"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Tripathi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V","family":"Tilak","sequence":"additional","affiliation":[{"name":"Department of Pathology, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221005, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B D","family":"Bhatia","sequence":"additional","affiliation":[{"name":"Department of Pediatrics"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2008,10,1]]},"reference":[{"key":"bibr-TD-07-0422C1","first-page":"1078","volume":"49","author":"Kumar R","year":"2001","journal-title":"J Assoc Phys India"},{"key":"bibr-TD-07-0422C2","first-page":"322","volume":"44","author":"Varma N","year":"1992","journal-title":"Trop Geogr Med"},{"key":"bibr-TD-07-0422C3","first-page":"399","volume":"42","author":"Tilak V","year":"1999","journal-title":"Indian J Pathol Microbiol"},{"key":"bibr-TD-07-0422C4","first-page":"375","volume":"45","author":"Khunger JM","year":"2002","journal-title":"Indian J Pathol Microbiol"},{"key":"bibr-TD-07-0422C5","doi-asserted-by":"publisher","DOI":"10.1093\/tropej\/fmi010"},{"key":"bibr-TD-07-0422C6","doi-asserted-by":"publisher","DOI":"10.1097\/00000441-199901000-00004"},{"key":"bibr-TD-07-0422C7","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1997.57.313"},{"key":"bibr-TD-07-0422C8","first-page":"469","volume":"37","author":"Arya TVS","year":"1989","journal-title":"J Assoc Phys India"},{"key":"bibr-TD-07-0422C9","first-page":"79","volume":"28","author":"Garewal G","year":"1991","journal-title":"Indian Pediatr"},{"key":"bibr-TD-07-0422C10","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1970.00310040115014"}],"container-title":["Tropical Doctor"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/td.2008.070422","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1258\/td.2008.070422","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/td.2008.070422","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,3]],"date-time":"2025-03-03T20:24:52Z","timestamp":1741033492000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1258\/td.2008.070422"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,10]]},"references-count":10,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2008,10]]}},"alternative-id":["10.1258\/td.2008.070422"],"URL":"https:\/\/doi.org\/10.1258\/td.2008.070422","relation":{},"ISSN":["0049-4755","1758-1133"],"issn-type":[{"value":"0049-4755","type":"print"},{"value":"1758-1133","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,10]]}}}