{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,16]],"date-time":"2025-12-16T12:13:47Z","timestamp":1765887227852,"version":"3.38.0"},"reference-count":10,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2010,5,17]],"date-time":"2010-05-17T00:00:00Z","timestamp":1274054400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Trop Doct"],"published-print":{"date-parts":[[2010,7]]},"abstract":"<jats:sec><jats:title>Summary<\/jats:title><jats:p> The present study discusses the clinical features and treatment outcomes during an outbreak caused by multidrug resistant (MDR) Salmonella typhi isolates from Van, Turkey. Of the 867 typhoid fever patients from the same village, 154 (17.8%) were hospitalised. A total of 42 (27.3%) cultures were positive. All S. typhi isolates were resistant to chloramphenicol, ampicillin and co-trimoxazole. Ceftriaxone was the most commonly used antibiotic (89%). It was found that the time-to-fever defervescence and the length of the hospital stay were greater for patients who were treated by ciprofloxacin than ceftriaxone ( P &lt;0.001). Inappropriate antibiotic treatment should be discouraged in order to prevent the development of resistant strains of S. typhi. <\/jats:p><\/jats:sec>","DOI":"10.1258\/td.2010.090438","type":"journal-article","created":{"date-parts":[[2010,5,18]],"date-time":"2010-05-18T03:04:12Z","timestamp":1274151852000},"page":"160-162","source":"Crossref","is-referenced-by-count":8,"title":["Multidrug resistant typhoid fever outbreak in Ercek Village\u2013Van, Eastern Anatolia, Turkey: clinical profile, sensitivity patterns and response to antimicrobials"],"prefix":"10.1177","volume":"40","author":[{"given":"Adalet","family":"Aypak","sequence":"first","affiliation":[{"name":"Department of Clinical Microbiology and Infectious Disease, Van Education and Research Hospital 65100, Van;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali Kutta","family":"\u00c7elik","sequence":"additional","affiliation":[{"name":"Department of Clinical Microbiology and Infectious Disease, Van Education and Research Hospital 65100, Van;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cenk","family":"Aypak","sequence":"additional","affiliation":[{"name":"Department of Family Medicine, Gevas Hospital 65110, Van;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00d6ztekin","family":"\u00c7ikman","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Van Education and Research Hospital 65100, Van, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2010,5,17]]},"reference":[{"key":"bibr1-td.2010.090438","first-page":"346","volume":"82","author":"Crump JA","year":"2004","journal-title":"Bull WHO"},{"key":"bibr2-td.2010.090438","first-page":"1","volume":"5","year":"2001","journal-title":"CD Alert"},{"unstructured":"National Institute of Communicable Diseases Investigation and Control of Water Borne Diseases. Directorate General of Health Services, 22 Shamnath Marg, New Delhi 1998; 1\u201333","key":"bibr3-td.2010.090438"},{"key":"bibr4-td.2010.090438","first-page":"17","volume":"22","author":"Wilke A","year":"1988","journal-title":"Mikrobiyol Bul"},{"key":"bibr5-td.2010.090438","first-page":"7","volume":"39","author":"Akan \u00d6","year":"1997","journal-title":"Turk J Ped"},{"key":"bibr6-td.2010.090438","first-page":"63","volume":"69","author":"Nasrallah SM","year":"1978","journal-title":"Am J Gastroenterol"},{"key":"bibr7-td.2010.090438","first-page":"1235","volume":"86","author":"Morgenstern R","year":"1991","journal-title":"Am J Gastroenterol"},{"doi-asserted-by":"publisher","key":"bibr8-td.2010.090438","DOI":"10.1177\/004947550003000404"},{"doi-asserted-by":"publisher","key":"bibr9-td.2010.090438","DOI":"10.1136\/adc.75.3.214"},{"key":"bibr10-td.2010.090438","first-page":"849","volume-title":"Manson's Tropical Diseases","author":"Mandal BK.","year":"2001","edition":"20"}],"container-title":["Tropical Doctor"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/td.2010.090438","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1258\/td.2010.090438","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/td.2010.090438","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,4]],"date-time":"2025-03-04T12:00:46Z","timestamp":1741089646000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1258\/td.2010.090438"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,5,17]]},"references-count":10,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2010,7]]}},"alternative-id":["10.1258\/td.2010.090438"],"URL":"https:\/\/doi.org\/10.1258\/td.2010.090438","relation":{},"ISSN":["0049-4755","1758-1133"],"issn-type":[{"type":"print","value":"0049-4755"},{"type":"electronic","value":"1758-1133"}],"subject":[],"published":{"date-parts":[[2010,5,17]]}}}