{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T13:58:59Z","timestamp":1753883939955,"version":"3.38.0"},"reference-count":11,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2010,8,13]],"date-time":"2010-08-13T00:00:00Z","timestamp":1281657600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Trop Doct"],"published-print":{"date-parts":[[2010,10]]},"abstract":"<jats:p> Following the occurrence of suspected cases of Vibrio cholerae in Karaj in 2008, this study was conducted in order to determine whether or not the cases were infected with cholera and, if so, to describe the prevalence of serotypes, route of transmission and the antimicrobial resistance profile. In this cross-sectional study, 6505 rectal swabs were collected from patients with acute gastroenteritis. Serotypes and biotypes of the isolates were determined by standard procedures. The antimicrobial susceptibility of 45 Inaba and 30 non-agglutinating (NAG) strains was determined. From 6505 specimens, 110 (1.69%) were defined as V. cholerae, including 70 (63.3%) V. cholerae O1 serotype Inaba biotype El Tor and 40 (36.4%) NAG Vibrios. The case fatality rate was 0.9%. Inaba strains were 100% resistant to nalidixic acid and amoxicillin, 95.7% resistant to trimethoprim-sulfamethoxazole, 91.3% resistant to furazolidone while the highest frequency of resistance in NAG Vibrios was 77.4% to erythromycin. The lowest resistance rate belonged to ciprofloxacin to which just one NAG strain was resistant. Results suggests an increase in resistance of V. cholerae to several antibiotics. Ciprofloxacin can still be used as first-line treatment of cholera in this region. <\/jats:p>","DOI":"10.1258\/td.2010.100015","type":"journal-article","created":{"date-parts":[[2010,8,14]],"date-time":"2010-08-14T01:10:16Z","timestamp":1281748216000},"page":"214-216","source":"Crossref","is-referenced-by-count":8,"title":["High prevalence of multidrug-resistant strains of <i>Vibrio cholerae<\/i>, in a cholera outbreak in Tehran\u2013Iran, during June\u2013September 2008"],"prefix":"10.1177","volume":"40","author":[{"given":"Mitra","family":"Ranjbar","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases, Firoozgar Hospital, Iran University of Medical Sciences, Tehran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elham","family":"Rahmani","sequence":"additional","affiliation":[{"name":"Medical Student Research Committee, Iran University of Medical Sciences and Health Services, Tehran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abas","family":"Nooriamiri","sequence":"additional","affiliation":[{"name":"Researcher, Health System, Iran University of Medical Sciences, Tehran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hossein","family":"Gholami","sequence":"additional","affiliation":[{"name":"Researcher, Health System, Iran University of Medical Sciences, Tehran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali","family":"Golmohamadi","sequence":"additional","affiliation":[{"name":"Researcher, Health System, Iran University of Medical Sciences, Tehran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hojatollah","family":"Barati","sequence":"additional","affiliation":[{"name":"Researcher, Health System, Iran University of Medical Sciences, Tehran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dina","family":"Rajabifar","sequence":"additional","affiliation":[{"name":"Medical Student Research Committee, Iran University of Medical Sciences and Health Services, Tehran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Somayeh","family":"Barati","sequence":"additional","affiliation":[{"name":"Medical Student Research Committee, Iran University of Medical Sciences and Health Services, Tehran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahdiyeh Shafiee","family":"Sabet","sequence":"additional","affiliation":[{"name":"Medical Student Research Committee, Iran University of Medical Sciences and Health Services, Tehran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alaleh","family":"Zamiri","sequence":"additional","affiliation":[{"name":"Medical Student Research Committee, Iran University of Medical Sciences and Health Services, Tehran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sama","family":"Haghighi","sequence":"additional","affiliation":[{"name":"Medical Student Research Committee, Iran University of Medical Sciences and Health Services, Tehran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pariva","family":"Taifehashemi","sequence":"additional","affiliation":[{"name":"Researcher, Health System, Iran University of Medical Sciences, Tehran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marziyeh","family":"Nojomi","sequence":"additional","affiliation":[{"name":"Department of Community Medicine, Iran University of Medical Sciences, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2010,8,13]]},"reference":[{"key":"bibr-TD-10-0015C1","volume-title":"Harrison's Principles of Internal Medicine","author":"Fauci AS","year":"2008","edition":"17"},{"key":"bibr-TD-10-0015C2","unstructured":"World Health Organization. Cholera. Fact sheet No. 107. 2000; revised November 2008. See http:\/\/www.who.int\/mediacentre\/factsheets\/fs107\/en\/index.html. (last checked 17 March 2009)"},{"key":"bibr-TD-10-0015C3","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2006.75.973"},{"key":"bibr-TD-10-0015C4","doi-asserted-by":"crossref","first-page":"174","DOI":"10.7883\/yoken.JJID.2006.174","volume":"59","author":"Izadi S","year":"2006","journal-title":"Jpn J Infect Dis"},{"key":"bibr-TD-10-0015C5","first-page":"768","volume":"14","author":"Keramat F","journal-title":"East Mediterr Health J 2008"},{"key":"bibr-TD-10-0015C6","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00632-06"},{"key":"bibr-TD-10-0015C7","first-page":"772","volume":"125","author":"Sur D","year":"2007","journal-title":"Indian J Med Res"},{"key":"bibr-TD-10-0015C8","unstructured":"KeshavarzA, HeydariN. A glance on water sources losses during production and consumption of agricultural production in Iran. 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