{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T04:43:41Z","timestamp":1768279421311,"version":"3.49.0"},"reference-count":20,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2011,5,16]],"date-time":"2011-05-16T00:00:00Z","timestamp":1305504000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Trop Doct"],"published-print":{"date-parts":[[2011,7]]},"abstract":"<jats:p> Seventy-six blood culture positive typhoid cases and forty-eight controls were studied. The typhidot test was positive in 74 (97.36%) cases, with a sensitivity, specificity and positive predictive value of 96%, 89.5%, and 95%, respectively, compared to the Widal test which was positive in 56 (73.68%) cases with a sensitivity, specificity, and positive predictive value of 72%, 87%, and 87%, respectively ( P = 0.001). In the control group, seven (14.5%) cases tested positive for the Widal test and two (4.16%) for the typhidot ( P = 0.001), yielding the sensitivity and specificity for the Widal test and the typhidot test of 63% and 83%, and 85% and 97%, respectively. We conclude that the Dot-EIA (enzyme immunoassay; typhidot) is a more sensitive and specific test which is easy to perform and more reliable compared to the Widal test and that it is useful in early therapy. <\/jats:p>","DOI":"10.1258\/td.2011.100406","type":"journal-article","created":{"date-parts":[[2011,5,17]],"date-time":"2011-05-17T01:58:41Z","timestamp":1305597521000},"page":"136-138","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["A comparative study of the typhidot (Dot-EIA) and Widal tests in blood culture positive cases of typhoid fever"],"prefix":"10.1177","volume":"41","author":[{"given":"Haji Khan","family":"Khoharo","sequence":"first","affiliation":[{"name":"Department of Medicine, Muhammad Medical College Hospital, Mirpurkhas, Sindh, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2011,5,16]]},"reference":[{"key":"bibr-TD-10-0406C1","first-page":"938","volume":"9","author":"Willke A","year":"2002","journal-title":"Clin Diagn Lab Immunol"},{"key":"bibr-TD-10-0406C2","first-page":"260","volume":"86","author":"Ochiai RL","year":"2008","journal-title":"Bull WHO"},{"key":"bibr-TD-10-0406C3","first-page":"421","volume":"2","author":"Wain J","year":"2008","journal-title":"J Infect Developing Countries"},{"key":"bibr-TD-10-0406C4","first-page":"260","volume":"86","author":"Ochiai RL","year":"2008","journal-title":"Bull WHO"},{"key":"bibr-TD-10-0406C5","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1999.61.654"},{"key":"bibr-TD-10-0406C6","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2672.1996.tb03216.x"},{"key":"bibr-TD-10-0406C7","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-291X(05)81417-2"},{"key":"bibr-TD-10-0406C8","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/19.1.172"},{"key":"bibr-TD-10-0406C9","doi-asserted-by":"publisher","DOI":"10.1016\/S0001-706X(98)00095-3"},{"key":"bibr-TD-10-0406C10","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1997.57.656"},{"key":"bibr-TD-10-0406C11","first-page":"2468","volume":"1","author":"Kawano RL","year":"2007","journal-title":"J Clin Microbiol"},{"key":"bibr-TD-10-0406C12","doi-asserted-by":"publisher","DOI":"10.3329\/bjmm.v3i1.2964"},{"key":"bibr-TD-10-0406C13","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/37.5.891"},{"key":"bibr-TD-10-0406C14","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(99)01001-6"},{"key":"bibr-TD-10-0406C15","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra020201"},{"key":"bibr-TD-10-0406C16","first-page":"9","volume":"51","author":"Pai AP","year":"2003","journal-title":"JAPI"},{"key":"bibr-TD-10-0406C17","first-page":"70","volume":"116","author":"Jesudasson M","year":"2002","journal-title":"Indian J Med Res"},{"key":"bibr-TD-10-0406C18","first-page":"244","volume":"5","author":"Sherwal BL","year":"2004","journal-title":"JIACM"},{"key":"bibr-TD-10-0406C19","doi-asserted-by":"publisher","DOI":"10.1016\/S0001-706X(98)00095-3"},{"key":"bibr-TD-10-0406C20","first-page":"495","volume":"43","author":"Gopalakrishan V","year":"2002","journal-title":"Singapore Med J"}],"container-title":["Tropical Doctor"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/td.2011.100406","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1258\/td.2011.100406","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/td.2011.100406","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,3]],"date-time":"2025-03-03T20:30:55Z","timestamp":1741033855000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1258\/td.2011.100406"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,5,16]]},"references-count":20,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2011,7]]}},"alternative-id":["10.1258\/td.2011.100406"],"URL":"https:\/\/doi.org\/10.1258\/td.2011.100406","relation":{},"ISSN":["0049-4755","1758-1133"],"issn-type":[{"value":"0049-4755","type":"print"},{"value":"1758-1133","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,5,16]]}}}