{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,4]],"date-time":"2025-03-04T05:42:39Z","timestamp":1741066959943,"version":"3.38.0"},"reference-count":8,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2011,11,11]],"date-time":"2011-11-11T00:00:00Z","timestamp":1320969600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Trop Doct"],"published-print":{"date-parts":[[2012,1]]},"abstract":"<jats:p> The emergence of multi-drug-resistant (MDR) strains has been a major obstacle in the tuberculosis (TB) control programme. In the present study we looked into the prevalence of MDR-TB in an urban tertiary care hospital in South India over four years (2007\u20132010). During this period, 641 clinical specimens (317 respiratory specimens and 324 non-respiratory specimens) were received for mycobacteriological culture and drug susceptibility testing for first-line drugs, using the BACTEC 460 TB system. Mycobacterium tuberculosis (MTB) was isolated in 34.8% ( n = 223) specimens. Of the total 223 MTB isolates 83 (37.2%) were MDR. Forty-two percent of the pulmonary MTB isolates ( n = 72) and 20.4% of the extra-pulmonary isolates ( n = 10) were MDR. Although we observed a high percentage of drug resistance, the prevalence of MDR was not observed to vary significantly within the four years which suggested good management. <\/jats:p>","DOI":"10.1258\/td.2011.110247","type":"journal-article","created":{"date-parts":[[2011,11,12]],"date-time":"2011-11-12T06:41:22Z","timestamp":1321080082000},"page":"35-37","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Multi-drug-resistant tuberculosis: the experience of an urban tertiary care hospital in South India using automated BACTEC 460 TB"],"prefix":"10.1177","volume":"42","author":[{"given":"Baijayanti","family":"Mishra","sequence":"first","affiliation":[{"name":"Department of Microbiology, St John's Medical College, Bangalore, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Smitha Mary","family":"Rockey","sequence":"additional","affiliation":[{"name":"Department of Microbiology, St John's Medical College, Bangalore, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soham","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Microbiology, St John's Medical College, Bangalore, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiresave","family":"Srinivasa","sequence":"additional","affiliation":[{"name":"Department of Microbiology, St John's Medical College, Bangalore, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sethumadhavan","family":"Muralidharan","sequence":"additional","affiliation":[{"name":"Department of Microbiology, St John's Medical College, Bangalore, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2011,11,11]]},"reference":[{"key":"bibr-TD-11-0247C1","doi-asserted-by":"publisher","DOI":"10.1016\/S0012-3692(15)50981-1"},{"key":"bibr-TD-11-0247C2","doi-asserted-by":"publisher","DOI":"10.4103\/0255-0857.31059"},{"key":"bibr-TD-11-0247C3","doi-asserted-by":"publisher","DOI":"10.4103\/0255-0857.25197"},{"key":"bibr-TD-11-0247C4","doi-asserted-by":"publisher","DOI":"10.4103\/0970-2113.56342"},{"key":"bibr-TD-11-0247C5","doi-asserted-by":"publisher","DOI":"10.1086\/374931"},{"key":"bibr-TD-11-0247C6","doi-asserted-by":"publisher","DOI":"10.3855\/jidc.669"},{"key":"bibr-TD-11-0247C7","first-page":"235","volume":"121","author":"Pereira M","year":"2005","journal-title":"Ind J Med Res"},{"key":"bibr-TD-11-0247C8","unstructured":"The World Health Organisation. Guidelines for the programmatic management of drug resistant tuberculosis. WHO\/HTM\/TB\/2006.361. Geneva: WHO, 2006"}],"container-title":["Tropical Doctor"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/td.2011.110247","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1258\/td.2011.110247","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/td.2011.110247","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,3]],"date-time":"2025-03-03T14:08:06Z","timestamp":1741010886000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1258\/td.2011.110247"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,11,11]]},"references-count":8,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,1]]}},"alternative-id":["10.1258\/td.2011.110247"],"URL":"https:\/\/doi.org\/10.1258\/td.2011.110247","relation":{},"ISSN":["0049-4755","1758-1133"],"issn-type":[{"type":"print","value":"0049-4755"},{"type":"electronic","value":"1758-1133"}],"subject":[],"published":{"date-parts":[[2011,11,11]]}}}