{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,2]],"date-time":"2025-03-02T14:40:29Z","timestamp":1740926429836,"version":"3.38.0"},"reference-count":8,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2012,4,19]],"date-time":"2012-04-19T00:00:00Z","timestamp":1334793600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Trop Doct"],"published-print":{"date-parts":[[2012,7]]},"abstract":"<jats:p> We conducted this prospective study among 110 symptomatic Plasmodium vivax patients attending the Kasturba Hospital, Manipal, India, in order to evaluate their clinico-laboratory profile during July 2007\u2013July 2009. Complications observed among patients were: anaemia (46.4%; 95% confidence interval [CI], 37.08\u201355.72%); thrombocytopenia (68.2%; 95% CI, 59.5\u201376.9%); leucopenia (29.1%; 95% CI, 20.61\u201337.59%); hyperbilirubinaemia (20%; 95% CI, 12.53\u201327.47%); non-oliguric renal failure (10.9%; 95% CI, 5.08\u201316.72%); elevated serum transaminases (33.6%; 95% CI, 24.77\u201342.43%); hypotension (8.2%; 95% CI, 3.07\u201313.33%); hepatomegaly (27.3%; 95% CI, 18.97\u201335.63%); and splenomegaly and jaundice in 12.7% (95% CI, 6.48\u201318.92%). The 99% chloroquine response and zero mortality observed in this study of vivax malaria are encouraging points for practicing physicians. <\/jats:p>","DOI":"10.1258\/td.2012.120038","type":"journal-article","created":{"date-parts":[[2012,4,21]],"date-time":"2012-04-21T00:13:14Z","timestamp":1334967194000},"page":"163-164","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["<i>Plasmodium vivax<\/i> remains responsive to chloroquine with primaquine treatment regimen: a prospective cohort study from tertiary care teaching hospital in southern India"],"prefix":"10.1177","volume":"42","author":[{"given":"Kavitha","family":"Saravu","sequence":"first","affiliation":[{"name":"Department of Interal Medicine, Kasturba Medical College, Manipal University, Manipal, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vasudeva","family":"Acharya","sequence":"additional","affiliation":[{"name":"Department of Interal Medicine, Kasturba Medical College, Manipal University, Manipal, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Krishna","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Interal Medicine, Kasturba Medical College, Manipal University, Manipal, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rishikesh","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Interal Medicine, Kasturba Medical College, Manipal University, Manipal, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2012,4,19]]},"reference":[{"key":"bibr-TD-12-0038C1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.0050128"},{"key":"bibr-TD-12-0038C2","doi-asserted-by":"publisher","DOI":"10.1038\/nature03342"},{"key":"bibr-TD-12-0038C3","doi-asserted-by":"publisher","DOI":"10.1258\/td.2011.110025"},{"key":"bibr-TD-12-0038C4","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2007.77.79"},{"key":"bibr-TD-12-0038C5","doi-asserted-by":"publisher","DOI":"10.1016\/j.pt.2007.08.011"},{"key":"bibr-TD-12-0038C6","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(08)70153-1"},{"volume-title":"Guidelines for the Treatment of Malaria","year":"2010","author":"World Health Organization","key":"bibr-TD-12-0038C7"},{"key":"bibr-TD-12-0038C8","first-page":"18","volume":"39","author":"Mohapatra MK","year":"2002","journal-title":"Ind J Malariol"}],"container-title":["Tropical Doctor"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/td.2012.120038","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1258\/td.2012.120038","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/td.2012.120038","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,2]],"date-time":"2025-03-02T13:40:46Z","timestamp":1740922846000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1258\/td.2012.120038"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,4,19]]},"references-count":8,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2012,7]]}},"alternative-id":["10.1258\/td.2012.120038"],"URL":"https:\/\/doi.org\/10.1258\/td.2012.120038","relation":{},"ISSN":["0049-4755","1758-1133"],"issn-type":[{"type":"print","value":"0049-4755"},{"type":"electronic","value":"1758-1133"}],"subject":[],"published":{"date-parts":[[2012,4,19]]}}}