{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,15]],"date-time":"2025-06-15T00:25:55Z","timestamp":1749947155254,"version":"3.33.0"},"reference-count":10,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2012,10,1]],"date-time":"2012-10-01T00:00:00Z","timestamp":1349049600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Trop Doct"],"published-print":{"date-parts":[[2012,10]]},"abstract":"<jats:sec><jats:title>Summary<\/jats:title><jats:p> Liver abscess (LA) is a common health problem among children in tropical countries. We conducted a prospective, observational study at a tertiary-care medical college in order to examine the clinico-socio-demographic profile and assess a possible association between certain predictors of a poor outcome in children admitted with LA. Of a total of 53 children, only 24.4% were malnourished. Staphylococcus aureus was the most common organism observed. Amoebic LA was noted in 7.5%. Right-sided pleural effusion was the most common complication recorded (20.7%). The most successful treatment modality was therapeutic percutaneous aspiration with antimicrobials (90.5% success). An elevated alkaline phosphatase and open surgery were associated with a poor outcome ( P = 0.04 in each case). The rate of hospital admissions of children with LA remains high and most are of pyogenic origin. Of the different treatment modalities, therapeutic aspiration along with antimicrobials achieved the best results. Raised alkaline phosphatase and open surgery were predictors of a poor outcome. <\/jats:p><\/jats:sec>","DOI":"10.1258\/td.2012.120266","type":"journal-article","created":{"date-parts":[[2013,2,12]],"date-time":"2013-02-12T16:18:45Z","timestamp":1360685925000},"page":"226-228","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Clinico-socio-demographic profile and predictors of poor outcome in children with liver abscess: a hospital-based study in northern India"],"prefix":"10.1177","volume":"42","author":[{"given":"Smita","family":"Ramachandran","sequence":"first","affiliation":[{"name":"Department of Paediatrics, Kalawati Saran Children's Hospital, Lady Hardinge Medical College, New Delhi, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kirtisudha","family":"Mishra","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Kalawati Saran Children's Hospital, Lady Hardinge Medical College, New Delhi, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Subhasis Roy","family":"Choudhury","sequence":"additional","affiliation":[{"name":"Department of Paediatric Surgery, Kalawati Saran Children's Hospital, Lady Hardinge Medical College, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rahul","family":"Saxena","sequence":"additional","affiliation":[{"name":"Department of Paediatric Surgery, Kalawati Saran Children's Hospital, Lady Hardinge Medical College, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2013,2,12]]},"reference":[{"key":"bibr1-td.2012.120266","first-page":"399","volume":"31","author":"Shamsuzzaman SM","year":"2000","journal-title":"Southeast Asian J Trop Med Public Health"},{"key":"bibr2-td.2012.120266","doi-asserted-by":"publisher","DOI":"10.1007\/s12519-010-0220-1"},{"key":"bibr3-td.2012.120266","first-page":"489","volume":"41","author":"Liew KV","year":"2000","journal-title":"Singapore Med J"},{"key":"bibr4-td.2012.120266","first-page":"1131","volume":"74","author":"Kumar N","year":"2007","journal-title":"Indian J Pediatr"},{"key":"bibr5-td.2012.120266","unstructured":"World Health Organization. Severe Acute Malnutrition. See http:\/\/www.who.int\/nutrition\/topics\/malnutrition\/en\/index.html (last checked 2 October 2011)"},{"key":"bibr6-td.2012.120266","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-011-1481-y"},{"key":"bibr7-td.2012.120266","doi-asserted-by":"publisher","DOI":"10.1007\/s00383-006-1812-7"},{"key":"bibr8-td.2012.120266","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1673.1982.tb02276.x"},{"key":"bibr9-td.2012.120266","doi-asserted-by":"publisher","DOI":"10.1186\/1756-0500-3-21"},{"key":"bibr10-td.2012.120266","doi-asserted-by":"publisher","DOI":"10.4103\/1319-3767.80384"}],"container-title":["Tropical Doctor"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/td.2012.120266","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1258\/td.2012.120266","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/td.2012.120266","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,27]],"date-time":"2025-01-27T20:36:05Z","timestamp":1738010165000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1258\/td.2012.120266"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,10]]},"references-count":10,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2012,10]]}},"alternative-id":["10.1258\/td.2012.120266"],"URL":"https:\/\/doi.org\/10.1258\/td.2012.120266","relation":{},"ISSN":["0049-4755","1758-1133"],"issn-type":[{"type":"print","value":"0049-4755"},{"type":"electronic","value":"1758-1133"}],"subject":[],"published":{"date-parts":[[2012,10]]}}}