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A new, heparin-bonded, expanded polytetrafluoroethylene graft (Gore Propaten vascular graft) designed to provide resistance to thrombosis may be associated with decreased early graft failure and increased patency. A concern with exposure to heparin, and therefore heparin-bonded prostheses, is the development of heparin-induced thrombocytopenia (HIT). Although rare, this requires prompt graft removal. We present a case to highlight this serious complication and review the literature on this topic. <\/jats:p>","DOI":"10.1258\/vasc.2011.cr0280","type":"journal-article","created":{"date-parts":[[2011,12,12]],"date-time":"2011-12-12T14:28:43Z","timestamp":1323700123000},"page":"338-341","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":15,"title":["Heparin-induced thrombocytopenia in the presence of a heparin-bonded bypass graft"],"prefix":"10.1177","volume":"19","author":[{"given":"M D","family":"Wheatcroft","sequence":"first","affiliation":[{"name":"Division of Vascular Surgery, Toronto General Hospital, UHN, Peter Munk Cardiac Centre, 200 Elizabeth Street, Toronto, ON, CanadaM5G 2C4"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E","family":"Greco","sequence":"additional","affiliation":[{"name":"Division of Vascular Surgery, Toronto General Hospital, UHN, Peter Munk Cardiac Centre, 200 Elizabeth Street, Toronto, ON, CanadaM5G 2C4"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L","family":"Tse","sequence":"additional","affiliation":[{"name":"Division of Vascular Surgery, Toronto General Hospital, UHN, Peter Munk Cardiac Centre, 200 Elizabeth Street, Toronto, ON, CanadaM5G 2C4"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G","family":"Roche-Nagle","sequence":"additional","affiliation":[{"name":"Division of Vascular Surgery, Toronto General Hospital, UHN, Peter Munk Cardiac Centre, 200 Elizabeth Street, Toronto, ON, CanadaM5G 2C4"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2011,10,18]]},"reference":[{"key":"bibr-VASC-03-11-CR-0280C1","doi-asserted-by":"publisher","DOI":"10.1016\/0741-5214(91)90212-D"},{"key":"bibr-VASC-03-11-CR-0280C2","doi-asserted-by":"publisher","DOI":"10.1016\/0741-5214(88)90009-2"},{"key":"bibr-VASC-03-11-CR-0280C3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2009.12.042"},{"key":"bibr-VASC-03-11-CR-0280C4","first-page":"195","volume":"50","author":"Hugl B","year":"2009","journal-title":"J Cardiovasc Surg (Torino)"},{"key":"bibr-VASC-03-11-CR-0280C5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2006.12.037"},{"key":"bibr-VASC-03-11-CR-0280C6","doi-asserted-by":"publisher","DOI":"10.1053\/ejvs.2002.1909"},{"key":"bibr-VASC-03-11-CR-0280C7","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000147537.72829.1B"},{"key":"bibr-VASC-03-11-CR-0280C8","doi-asserted-by":"publisher","DOI":"10.1007\/s11239-011-0569-6"},{"key":"bibr-VASC-03-11-CR-0280C9","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp052967"},{"key":"bibr-VASC-03-11-CR-0280C10","doi-asserted-by":"publisher","DOI":"10.1378\/chest.07-0425"},{"key":"bibr-VASC-03-11-CR-0280C11","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199505183322003"},{"key":"bibr-VASC-03-11-CR-0280C12","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2007.10.005"},{"key":"bibr-VASC-03-11-CR-0280C13","doi-asserted-by":"publisher","DOI":"10.1016\/S0741-5214(98)70270-8"},{"key":"bibr-VASC-03-11-CR-0280C14","doi-asserted-by":"publisher","DOI":"10.1016\/j.avsg.2007.07.016"},{"key":"bibr-VASC-03-11-CR-0280C15","doi-asserted-by":"publisher","DOI":"10.1016\/0741-5214(88)90011-0"},{"key":"bibr-VASC-03-11-CR-0280C16","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2008.12.004"},{"key":"bibr-VASC-03-11-CR-0280C17","doi-asserted-by":"publisher","DOI":"10.1001\/jama.289.7.853"}],"container-title":["Vascular"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/vasc.2011.cr0280","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1258\/vasc.2011.cr0280","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1258\/vasc.2011.cr0280","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,2]],"date-time":"2025-03-02T20:02:03Z","timestamp":1740945723000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1258\/vasc.2011.cr0280"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,10,18]]},"references-count":17,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2011,12]]}},"alternative-id":["10.1258\/vasc.2011.cr0280"],"URL":"https:\/\/doi.org\/10.1258\/vasc.2011.cr0280","relation":{},"ISSN":["1708-5381","1708-539X"],"issn-type":[{"value":"1708-5381","type":"print"},{"value":"1708-539X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,10,18]]}}}