{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T14:04:54Z","timestamp":1753884294877,"version":"3.41.2"},"reference-count":18,"publisher":"Oxford University Press (OUP)","issue":"1044","license":[{"start":{"date-parts":[[2014,11,19]],"date-time":"2014-11-19T00:00:00Z","timestamp":1416355200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,12,1]]},"abstract":"\n Objectives:<\/jats:title>\n (a) To compare radiologists' breast mammographic density readings with CT subjective measures. (b) To correlate computer-derived measurement of CT density with subjective assessments. (c) To evaluate density distributions in this cohort of patients with breast cancer.<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n A retrospective review of mammograms and CT scans in 77 patients with breast cancer obtained within 1 year of each other was performed. Two radiologists independently reviewed both CT and mammograms and classified each case into four categories as defined by the breast imaging-reporting and data system of the American College of Radiology. Inter-reader agreements were obtained for both mammographic and CT density subjective evaluations by using the Cohen-weighted kappa statistic and Spearman correlation. The semi-automated computer-derived measurement of breast density was correlated with visual measurements.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n Inter-reader agreements were lower for subjective CT density grades than those for mammographic readings 0.428 [confidence interval (CI), 0.24\u20130.89] vs 0.571 (CI, 0.35\u20130.76). There was moderately good correlation between subjective CT density grades and the mammographic density grades for both readers (0.760 for Reader 1 and 0.913 for Reader 2). The semi-automated CT density measurement correlated well with the subjective assessments, with complete agreement of the density grades in 84.9% of patients and only one level difference in the rest.<\/jats:p>\n <\/jats:sec>\n \n Conclusions:<\/jats:title>\n Semi-automated CT density measurements in the evaluation of breast density correlated well with subjective mammographic density measurement.<\/jats:p>\n <\/jats:sec>\n \n Advances in knowledge:<\/jats:title>\n There is good correlation between CT and mammographic density, but further studies are needed on how to incorporate semi-automated CT breast density measurement in the risk stratification of patients.<\/jats:p>\n <\/jats:sec>","DOI":"10.1259\/bjr.20140530","type":"journal-article","created":{"date-parts":[[2014,11,6]],"date-time":"2014-11-06T09:31:19Z","timestamp":1415266279000},"source":"Crossref","is-referenced-by-count":2,"title":["How does semi-automated computer-derived CT measure of breast density compare with subjective assessments to assess mean glandular breast density, in patients with breast cancer?"],"prefix":"10.1093","volume":"87","author":[{"given":"G J","family":"Bansal","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Kotugodella","sequence":"additional","affiliation":[{"name":"The Breast Centre, University Hospital of Llandough, Penarth, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2014,11,19]]},"reference":[{"key":"2024050403285413500_b1","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1007\/978-1-60327-492-0_15","article-title":"Mammographic density: a heritable risk factor for breast cancer","volume":"472","author":"Boyd","year":"2009","journal-title":"Methods Mol Biol"},{"key":"2024050403285413500_b2","doi-asserted-by":"publisher","first-page":"571","DOI":"10.1007\/s10549-012-2185-3","article-title":"Mammographic density and breast cancer 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