{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T13:51:27Z","timestamp":1780494687182,"version":"3.54.1"},"reference-count":27,"publisher":"Oxford University Press (OUP)","issue":"1079","license":[{"start":{"date-parts":[[2017,10,20]],"date-time":"2017-10-20T00:00:00Z","timestamp":1508457600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,11,1]]},"abstract":"<jats:p>Contrast-enhanced radiological examinations are important diagnostic tools in modern medicine. Currently, all approved and available iodinated and gadolinium-based contrast agents are safe and well-tolerated by most patients. However, approximately 2% of patients receiving iodinated contrast media exhibit hypersensitivity reactions. Patients with a history of such a reaction are at increased risk upon reexposure. Therefore, they are subjected to a prophylaxis such as injection of antiallergy drugs or general anaesthesia. The latter procedure is expensive, can burden the patients organism, and besides lacks objective verification. Therefore, the purpose of our review paper is to present and discuss the background and the previous practice, as well as to provide a proposal for a safe individual patient management.<\/jats:p>","DOI":"10.1259\/bjr.20160647","type":"journal-article","created":{"date-parts":[[2017,9,7]],"date-time":"2017-09-07T00:56:09Z","timestamp":1504745769000},"source":"Crossref","is-referenced-by-count":5,"title":["General anaesthesia for patients with a history of a contrast medium-induced anaphylaxis: a useful prophylaxis?"],"prefix":"10.1093","volume":"90","author":[{"given":"Ingrid","family":"Boehm","sequence":"first","affiliation":[{"name":"Department of Diagnostic, Interventional and Pediatric Radiology, Inselspital, University of Bern, Bern, Switzerland"},{"name":"Radiology Laboratory, Department of BioMedical Research, University of Bern, Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Knud","family":"Nairz","sequence":"additional","affiliation":[{"name":"Department of Diagnostic, Interventional and Pediatric Radiology, Inselspital, University of Bern, Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Morelli","sequence":"additional","affiliation":[{"name":"Department of Radiology, St. John\u2019s Medical Center Tulsa, Tulsa, OK, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia","family":"Silva Hasembank Keller","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, B\u00fcrgerspital Solothurn, Solothurn, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes Thomas","family":"Heverhagen","sequence":"additional","affiliation":[{"name":"Department of Diagnostic, Interventional and Pediatric Radiology, Inselspital, University of Bern, Bern, Switzerland"},{"name":"Radiology Laboratory, Department of BioMedical Research, University of Bern, Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2017,10,20]]},"reference":[{"key":"2024050214355773000_R1","doi-asserted-by":"crossref","first-page":"2277","DOI":"10.1056\/NEJMra072149","article-title":"Computed tomography\u2014an increasing source of radiation exposure","volume":"357","author":"Brenner","year":"2007","journal-title":"N Engl J Med"},{"key":"2024050214355773000_R2","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1148\/radiol.10100640","article-title":"National trends in CT use in the emergency department: 1995-2007","volume":"258","author":"Larson","year":"2011","journal-title":"Radiology"},{"key":"2024050214355773000_R3","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.2214\/AJR.07.3606","article-title":"\"Acute reactions to urographic contrast medium: incidence, clinical characteristics, and relationship to history of hypersensitivity states\"\u2014a commentary","volume":"190","author":"Katzberg","year":"2008","journal-title":"AJR Am J Roentgenol"},{"key":"2024050214355773000_R4","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.2214\/ajr.176.6.1761389","article-title":"Breakthrough adverse reactions to low-osmolar contrast media after steroid premedication","volume":"176","author":"Freed","year":"2001","journal-title":"AJR Am J Roentgenol"},{"key":"2024050214355773000_R5","doi-asserted-by":"crossref","first-page":"187","DOI":"10.2214\/AJR.07.2718","article-title":"Allergic-like breakthrough reactions to gadolinium contrast agents after corticosteroid and antihistamine premedication","volume":"190","author":"Dillman","year":"2008","journal-title":"AJR Am J Roentgenol"},{"key":"2024050214355773000_R6","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1016\/S0248-8663(01)00455-6","article-title":"Anaphylactoid reactions and late skin reactions to iodinated contrast media: present state of the question \u2013 idea development","volume":"22","author":"Moneret-Vautrin","year":"2001","journal-title":"Rev Med Interne"},{"key":"2024050214355773000_R7","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1055\/s-2008-1027771","article-title":"Contrast medium induced anaphylaxis and prevention by selecting a compatible contrast agent","volume":"180","author":"B\u00f6hm","year":"2008","journal-title":"Rofo"},{"key":"2024050214355773000_R8","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1097\/00000542-198401000-00010","article-title":"Systemic reactions to intravascular contrast media. 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