{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T11:15:44Z","timestamp":1785842144554,"version":"3.56.0"},"reference-count":21,"publisher":"Oxford University Press (OUP)","issue":"1084","license":[{"start":{"date-parts":[[2018,1,18]],"date-time":"2018-01-18T00:00:00Z","timestamp":1516233600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,4,1]]},"abstract":"<jats:sec>\n                  <jats:title>Objective:<\/jats:title>\n                  <jats:p>Hyperintense area on T \u00a01\u00a0weighted images (T \u00a01 HIA) have been reported as suggestive features of uterine leiomyosarcoma (LMS), but differentiating LMS from leiomyoma (LM) is often difficult. This study aimed to evaluate the differences between uterine LMS and LM demonstrating intratumoral T \u00a01 HIA.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods:<\/jats:title>\n                  <jats:p>MRI was performed in 509 patients with 1137 uterine smooth muscle tumours [14 LMSs, 5 smooth muscle tumours of uncertain malignant potential , and 1118 LMs] which exceeded 3\u2009cm in diameter. LM with red degeneration and lipoleiomyoma were excluded from the study. We retrospectively reviewed the images and assessed T \u00a01 HIA within tumours.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>T \u00a01 HIAs were observed in 11\/14 (78.6%) LMSs, 0\/5 (0%) smooth muscle tumours of uncertain malignant potential, and 15\/1118 (1.3%) LMs. T \u00a01 HIAs were more homogenous (53 vs 0%, p &amp;lt; 0.01) and more well-demarcated (60 vs 9%, p &amp;lt; 0.05) in LMs than in LMSs. T \u00a02 hypointense rim within T \u00a01 HIA (53 vs 9%, p &amp;lt; 0.05) was more frequently observed in LMs than in LMSs. The occupying rate of T \u00a01 HIA (0.20 \u00b1 0.24 vs 0.42 \u00b1 0.27, p &amp;lt; 0.05) was smaller in LMs than in LMSs. The signal intensity ratio of T \u00a01 HIA (1.83 \u00b1 0.36 vs 1.38 \u00b1 0.23, p &amp;lt; 0.01) was greater in LMs than in LMSs.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion:<\/jats:title>\n                  <jats:p>T \u00a01 HIA within LM showed more homogeneity, better demarcation, smaller occupying rate, and higher signal intensity than T \u00a01 HIA within LMS.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Advances in knowledge:<\/jats:title>\n                  <jats:p>The differences in T \u00a01 HIA within tumours may be useful for differentiating between LMS and LM.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1259\/bjr.20170767","type":"journal-article","created":{"date-parts":[[2018,1,8]],"date-time":"2018-01-08T15:14:31Z","timestamp":1515424471000},"source":"Crossref","is-referenced-by-count":17,"title":["Uterine smooth muscle tumours with hyperintense area on <i>T<\/i>\n\u00a01\u00a0weighted images: differentiation between leiomyosarcomas and leiomyomas"],"prefix":"10.1093","volume":"91","author":[{"given":"Tomohiro","family":"Ando","sequence":"first","affiliation":[{"name":"Department of Radiology, Gifu University School of Medicine , Gifu , Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroki","family":"Kato","sequence":"additional","affiliation":[{"name":"Department of Radiology, Gifu University School of Medicine , Gifu , Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatsuro","family":"Furui","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Gifu University School of Medicine , Gifu , Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ken-ichirou","family":"Morishige","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Gifu University School of Medicine , Gifu , 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