{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T18:30:28Z","timestamp":1778178628692,"version":"3.51.4"},"reference-count":22,"publisher":"Oxford University Press (OUP)","issue":"1093","license":[{"start":{"date-parts":[[2018,9,21]],"date-time":"2018-09-21T00:00:00Z","timestamp":1537488000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,1,1]]},"abstract":"<jats:sec>\n                  <jats:title>Objective:<\/jats:title>\n                  <jats:p>To evaluate the ability of a model-based iterative reconstruction (MBIR) for improving image quality in upper abdominal CT with quarter of the normal dose, in comparison with adaptive statistical iterative reconstruction (ASiR) at normal dose.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods:<\/jats:title>\n                  <jats:p>40 upper abdominal patients were randomly divided into two groups: normal-dose group (n = 20) with tube current modulation for noise index (NI) of 10 HU and 40% ASiR reconstruction; low-dose group (n = 20) with NI = 20 \u2009HU in the delay phase and MBIR and 40%ASiR. Images in the delay phase were compared. The CT values and standard deviation (SD) values of the liver, spleen, pancreas, kidney, erector spine and fat were measured. Contrast-noise-ratio (CNR = (CTtissue-CT fat)\/SDfat) of each measured organ were calculated and compared with one-way ANOVA among the three reconstruction groups. The subjective image scores of the three groups were assessed blindly by two experienced physicians using a 5-point system and the score consistency was compared by the \u03ba test.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results:<\/jats:title>\n                  <jats:p>Dose reduction of 75 % was achieved for the low-dose scan. The subjective scores (95 % confidence intervals) of the three groups (NI 10\u201340 % \u2009ASiR, NI 20\u201340% \u2009ASiR and NI 20-MBIR) were 4.00 \u00b1 0.79 (3.62\u20134.37), 3.35 \u00b1 0.58 (3.07\u20133.62) and 3.90 \u00b1 0.64 (3.60\u20134.19), respectively with no difference between the NI 10\u201340% \u2009ASiR and NI20-MBIR groups and good consistency between reviewers (\u03ba = 0.726). MBIR had statistically lower SD values and higher contrast-to-noise ratio values in the liver, spleen, pancreas, kidney and erector spine than NI 10\u201340% \u2009ASiR and NI 20\u201340% \u2009ASiR (all p &amp;lt; 0.05).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion:<\/jats:title>\n                  <jats:p>At 75 % dose reduction, MBIR provides similar image quality compared to 40% ASiR at normal-dose.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Advances in knowledge:<\/jats:title>\n                  <jats:p>MBIR provides good image quality at 25 % of the normal dose.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1259\/bjr.20180137","type":"journal-article","created":{"date-parts":[[2018,9,21]],"date-time":"2018-09-21T16:39:10Z","timestamp":1537547950000},"source":"Crossref","is-referenced-by-count":4,"title":["Improving image quality with model-based iterative 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