{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T20:53:25Z","timestamp":1765486405679,"version":"3.41.2"},"reference-count":48,"publisher":"Oxford University Press (OUP)","issue":"1110","license":[{"start":{"date-parts":[[2020,4,10]],"date-time":"2020-04-10T00:00:00Z","timestamp":1586476800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,5,1]]},"abstract":"<jats:sec>\n                  <jats:title>Objectives:<\/jats:title>\n                  <jats:p>To estimate risk for exposure-induced cancer death (REID), organ-specific risks of exposure-induced cancer death (REIDHT) and associated conversion coefficients (CCREID:KAP=REID\/kerma-area product (KAP), CCREIDHT:KAP=REIDHT\/KAP) in paediatric cardiac catheterizations using data from radiation dose structured reports (RDSR). A novel risk surveillance tool consisting of age-specific and gender-specific risk reference values (RRVs) related to population cancer risk is suggested.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods:<\/jats:title>\n                  <jats:p>The PCXMC v.2.0 code is used together with exposure-related information from RDSR from a cohort of 238 children to assess cancer risks and related conversion coefficients. The KAP corresponding to 1 in 1000 of increased REID is used to define age-specific and gender-specific KAP values to monitor risk in such patient cohorts, here denoted as RRVs.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results:<\/jats:title>\n                  <jats:p>The REID estimates ranged from below 1 up to 300 in 100,000, and the RRVs for the different age groups and gender ranged from 0.77 Gycm2 and 2.1 Gycm2 for neonates (female, male) to 11 Gycm2 and 25 Gycm2 for 15-year-olds (female, male). The CCREID:KAP and CCREIDHT:KAP decreased biexponentially with increased age, being notably higher for female patients.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions:<\/jats:title>\n                  <jats:p>Prominent risk contributing organs were the lungs and the (female) breast. The concept of age-specific and gender-specific RRVs related to population cancer risk is introduced and is intended to be used as a supporting tool for physicians performing such interventions.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Advances in knowledge:<\/jats:title>\n                  <jats:p>Age-related and gender-related conversion coefficients for radiation risk, CCREID:KAP and CCREIDHT:KAP, are introduced and a novel risk surveillance concept, the RRV, is suggested for paediatric cardiac catheterizations.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1259\/bjr.20190869","type":"journal-article","created":{"date-parts":[[2020,4,3]],"date-time":"2020-04-03T14:56:59Z","timestamp":1585925819000},"source":"Crossref","is-referenced-by-count":6,"title":["Age-specific and gender-specific radiation risks in paediatric angiography and interventional cardiology: conversion coefficients and risk reference values"],"prefix":"10.1093","volume":"93","author":[{"given":"Angeliki","family":"Karambatsakidou","sequence":"first","affiliation":[{"name":"Department of Medical Radiation Physics and Nuclear Medicine, Karolinska University Hospital , 171 76 Stockholm , Sweden"},{"name":"Department of Oncology-Pathology, Karolinska Institutet , 171 76 Stockholm , Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristoffer","family":"Steiner","sequence":"additional","affiliation":[{"name":"Department of Women's and Children's Health, Karolinska Institutet , 171 76 Stockholm , Sweden"},{"name":"Department of Paediatric Cardiology, Karolinska University Hospital, Astrid Lindgrens Children\u00b4s Hospital Solna , 171 76 Stockholm , Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annette","family":"Fransson","sequence":"additional","affiliation":[{"name":"Department of Medical Radiation Physics and Nuclear Medicine, Karolinska University Hospital , 171 76 Stockholm , Sweden"},{"name":"Department of Oncology-Pathology, Karolinska Institutet , 171 76 Stockholm , Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gavin","family":"Poludniowski","sequence":"additional","affiliation":[{"name":"Department of Medical Radiation Physics and Nuclear Medicine, Karolinska University Hospital , 171 76 Stockholm , Sweden"},{"name":"Department of Oncology-Pathology, Karolinska Institutet , 171 76 Stockholm , Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2020,4,10]]},"reference":[{"key":"2024050215231601200_b1","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1161\/CIRCULATIONAHA.106.627224","article-title":"Congenital heart disease in the general population: changing prevalence and age distribution","volume":"115","author":"Marelli","year":"2007","journal-title":"Circulation"},{"volume-title":"Report to the general gssembly, with scientific annexes","year":"2006","author":"United Nations Scientific Committee on the Effects of Atomic Radiation","key":"2024050215231601200_b2"},{"key":"2024050215231601200_b3","article-title":"Avoidance of radiation injuries from medical interventional procedures. 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