{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T03:35:12Z","timestamp":1773027312880,"version":"3.50.1"},"reference-count":16,"publisher":"Oxford University Press (OUP)","issue":"1117","license":[{"start":{"date-parts":[[2020,10,8]],"date-time":"2020-10-08T00:00:00Z","timestamp":1602115200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,1,1]]},"abstract":"<jats:sec>\n                  <jats:title>Objectives:<\/jats:title>\n                  <jats:p>This work establishes the prototype of a new innovative risk model that aims to evaluate the total risk involved with screening mammography for each individual female. This has been specifically designed to accommodate any combination of lifetime screening regimes, using only the information gathered from a single mammographic examination.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods:<\/jats:title>\n                  <jats:p>This model prototype was developed with the aid of a large dataset of images from the Cancer Institute New South Wales (CINSW) with over 30,000 images from over 7000 examinations. Each examination is derived from a separate female.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results:<\/jats:title>\n                  <jats:p>This prototype which we have called Breast Individualised Risk of Radiation-Induced Screening Cancer (Breast-iRRISC) is a novel tool for the assessment of the lifetime risk involved with screening mammography. The results demonstrate the applicability of this approach to the various screening regimes utilised around the globe, in addition to the personalised screening frequency patterns females have undergone and are likely to receive in the future.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions:<\/jats:title>\n                  <jats:p>This unique tailored approach to risk assessment will further empower females and clinicians towards a more informed clinical decision process regarding future imaging pathways. It will also inform health policy decisions regarding alternate screening durations and intervals.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Advances in knowledge:<\/jats:title>\n                  <jats:p>Breast-iRRISC is a novel tool that provides females, clinicians and health policymakers around the globe with the ability to quantify the lifetime risk of radiation-induced breast cancer from screening mammography on an individual level from a single exposure.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1259\/bjr.20200734","type":"journal-article","created":{"date-parts":[[2020,10,8]],"date-time":"2020-10-08T21:56:31Z","timestamp":1602194191000},"source":"Crossref","is-referenced-by-count":5,"title":["Breast-iRRISC: a novel model for predicting the individualised lifetime risk of radiation-induced breast cancer from a single screening event"],"prefix":"10.1093","volume":"94","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0288-5020","authenticated-orcid":false,"given":"Sahand","family":"Hooshmand","sequence":"first","affiliation":[{"name":"Faculty of Medicine and Health, The University of Sydney, Cumberland Campus, 75 East St, Lidcombe , Sydney, NSW 2141 , Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Warren M.","family":"Reed","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Health, The University of Sydney, Cumberland Campus, 75 East St, Lidcombe , Sydney, NSW 2141 , Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mo\u2019ayyad E.","family":"Suleiman","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Health, The University of Sydney, Cumberland Campus, 75 East St, Lidcombe , Sydney, NSW 2141 , Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick C.","family":"Brennan","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Health, The University of Sydney, Cumberland Campus, 75 East St, Lidcombe , Sydney, NSW 2141 , Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2020,10,8]]},"reference":[{"key":"2024050215420821800_b1","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1007\/s00411-006-0029-4","article-title":"Estimating radiation-induced cancer risks at very low doses: rationale for using a linear no-threshold approach","volume":"44","author":"Brenner","year":"2006","journal-title":"Radiat Environ Biophys"},{"issue":"2-4","key":"2024050215420821800_b2","first-page":"1","article-title":"The 2007 recommendations of the International Commission on radiological protection. ICRP publication 103","volume":"37","year":"2007","journal-title":"Ann ICRP"},{"key":"2024050215420821800_b3","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1667\/0033-7587(2002)158[0220:REOBCR]2.0.CO;2","article-title":"Radiation effects on breast cancer risk: a pooled analysis of eight cohorts","volume":"158","author":"Preston","year":"2002","journal-title":"Radiat Res"},{"key":"2024050215420821800_b4","doi-asserted-by":"crossref","first-page":"205","DOI":"10.7326\/M15-1241","article-title":"Radiation-Induced breast cancer incidence and mortality from digital mammography screening: a modeling study","volume":"164","author":"Miglioretti","year":"2016","journal-title":"Ann Intern Med"},{"key":"2024050215420821800_b5","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1111\/1754-9485.12540","article-title":"Diagnostic reference levels for digital mammography in New South Wales","volume":"61","author":"Suleiman","year":"2017","journal-title":"J Med Imaging Radiat Oncol"},{"key":"2024050215420821800_b6","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1148\/radiol.10100655","article-title":"Risk of radiation-induced breast cancer from mammographic screening","volume":"258","author":"Yaffe","year":"2011","journal-title":"Radiology"},{"key":"2024050215420821800_b7","doi-asserted-by":"crossref","DOI":"10.1259\/bjr.20150897","article-title":"Radiation risk of breast screening in England with digital mammography","volume":"89","author":"Warren","year":"2016","journal-title":"Br J Radiol"},{"key":"2024050215420821800_b8","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1016\/j.jmir.2018.06.005","article-title":"Calculating individual lifetime effective risk from initial mean glandular dose arising from the first screening mammogram","volume":"49","author":"M Ali","year":"2018","journal-title":"J Med Imaging Radiat Sci"},{"key":"2024050215420821800_b9","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.ejrad.2017.10.003","article-title":"Mathematical modelling of radiation-induced cancer risk from breast screening by mammography","volume":"96","author":"M Ali","year":"2017","journal-title":"Eur J Radiol"},{"key":"2024050215420821800_b10","doi-asserted-by":"crossref","DOI":"10.1259\/bjr.20180032","article-title":"Integrating mammographic breast density in glandular dose calculation","volume":"91","author":"Suleiman","year":"2018","journal-title":"Br J Radiol"},{"key":"2024050215420821800_b11","doi-asserted-by":"crossref","first-page":"3225","DOI":"10.1088\/0031-9155\/45\/11\/308","article-title":"Additional factors for the estimation of mean glandular breast dose using the UK mammography dosimetry protocol","volume":"45","author":"Dance","year":"2000","journal-title":"Phys Med Biol"},{"key":"2024050215420821800_b12","volume-title":"editor. Luxembourg: Office for Official Publications of the European Communities","author":"Perry","year":"2006","edition":"4th ed"},{"key":"2024050215420821800_b13","volume-title":"editor. Chichester: Wiley","author":"Mansfield","year":"2012","edition":"2nd ed."},{"issue":"3-4","key":"2024050215420821800_b14","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.icrp.2012.07.001","article-title":"We can do better than effective dose for estimating or comparing low-dose radiation risks","volume":"41","author":"Brenner","year":"2012","journal-title":"Ann ICRP"},{"key":"2024050215420821800_b15","article-title":"Health risks from exposure to low levels of ionizing radiation: BEIR VII, Phase 2","year":"2006","journal-title":"Washington, D.C: National Academies Press"},{"key":"2024050215420821800_b16","unstructured":"Breastcancer.org.\n          \n\u00a0Risk of Developing Breast Cancer 2018\n.\nupdated 20 December, 2018. Available from\n. Available from:\nhttps:\/\/www.breastcancer.org\/symptoms\/understand_bc\/risk\/understanding#:~:text=On%20average%2C%20an%20individual%20woman,are%2C%20the%20lower%20the%20risk\n."}],"container-title":["The British Journal of Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/bjr\/article-pdf\/94\/1117\/20200734\/57373399\/bjr.20200734.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bjr\/article-pdf\/94\/1117\/20200734\/57373399\/bjr.20200734.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,2]],"date-time":"2024-05-02T16:36:41Z","timestamp":1714667801000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bjr\/article\/doi\/10.1259\/bjr.20200734\/7460360"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10,8]]},"references-count":16,"journal-issue":{"issue":"1117","published-online":{"date-parts":[[2020,10,8]]},"published-print":{"date-parts":[[2021,1,1]]}},"URL":"https:\/\/doi.org\/10.1259\/bjr.20200734","relation":{},"ISSN":["0007-1285","1748-880X"],"issn-type":[{"value":"0007-1285","type":"print"},{"value":"1748-880X","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2021,1,1]]},"published":{"date-parts":[[2020,10,8]]},"article-number":"20200734"}}