{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T02:50:42Z","timestamp":1787021442977,"version":"build-2736575974"},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"1125","license":[{"start":{"date-parts":[[2021,5,21]],"date-time":"2021-05-21T00:00:00Z","timestamp":1621555200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,9,1]]},"abstract":"<jats:p>Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is a rare and newly recognized subtype of T cell Non-Hodgkin Lymphoma (NHLs) associated with breast implants.<\/jats:p>\n                  <jats:p>The mechanism involved in the development of this kind of lymphoma is still uncertain.<\/jats:p>\n                  <jats:p>BIA-ALCL is generally an indolent disease localized to the breast implant and its capsule and effectively treated with capsulectomy alone without chemotherapy.<\/jats:p>\n                  <jats:p>Clinically, BIA-ALCL may typically present a sudden-onset breast-swelling secondary to periimplant effusion. The minority of BIA-ALCL patients present a more aggressive mass-forming subtype, for which systemic therapy is mandatory.<\/jats:p>\n                  <jats:p>Despite the number of cases has recently increased, BIA-ALCL remains a rare disease described mainly in several case reports and small case series.<\/jats:p>\n                  <jats:p>Breast imaging, including mammography, ultrasound and breast MRI are routinely used in the screening of breast cancer; however, guidelines for the imaging and pathological diagnosis of this disease have only recently been proposed and included in the 2019 National Comprehensive Cancer Network (NCCN) consensus guidelines for BIA-ALCL.<\/jats:p>\n                  <jats:p>The main purpose of this pictorial is to illustrate the MRI signs of BIA-ALCL and correlate them with the corresponding pathology features in order to improve the knowledge of the principals MRI features of this type of lymphoma.<\/jats:p>","DOI":"10.1259\/bjr.20210093","type":"journal-article","created":{"date-parts":[[2021,5,14]],"date-time":"2021-05-14T15:35:55Z","timestamp":1621006555000},"source":"Crossref","is-referenced-by-count":12,"title":["MRI features of breast implant-associated anaplastic large cell lymphoma"],"prefix":"10.1093","volume":"94","author":[{"given":"Anna","family":"Rotili","sequence":"first","affiliation":[{"name":"Division of Breast Radiology, IEO - European Institute of Oncology IRCCS , Milan , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federica","family":"Ferrari","sequence":"additional","affiliation":[{"name":"Division of Breast Radiology, IEO - European Institute of Oncology IRCCS , Milan , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Nicosia","sequence":"additional","affiliation":[{"name":"Division of Breast Radiology, IEO - European Institute of Oncology IRCCS , Milan , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filippo","family":"Pesapane","sequence":"additional","affiliation":[{"name":"Division of Breast Radiology, IEO - European Institute of Oncology IRCCS , Milan , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valentina","family":"Tabanelli","sequence":"additional","affiliation":[{"name":"Division of Diagnostic Hematopathology, IEO - European Institute of Oncology IRCCS , Milan , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Fiori","sequence":"additional","affiliation":[{"name":"Division of Diagnostic Hematopathology, IEO - European Institute of Oncology IRCCS , Milan , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Vanazzi","sequence":"additional","affiliation":[{"name":"Division of Hemato-Oncology, IEO - European Institute of Oncology IRCCS , Milan , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorenza","family":"Meneghetti","sequence":"additional","affiliation":[{"name":"Division of Breast Radiology, IEO - European Institute of Oncology IRCCS , Milan , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Abbate","sequence":"additional","affiliation":[{"name":"Division of Breast Radiology, IEO - European Institute of Oncology IRCCS , Milan , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antuono","family":"Latronico","sequence":"additional","affiliation":[{"name":"Division of Breast Radiology, IEO - European Institute of Oncology IRCCS , Milan , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enrico","family":"Cassano","sequence":"additional","affiliation":[{"name":"Division of Breast Radiology, IEO - European Institute of Oncology IRCCS , Milan , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2021,5,21]]},"reference":[{"key":"2024050215121295700_b1","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1148\/rg.2020190198","article-title":"Breast implant-associated anaplastic large cell lymphoma: review and multiparametric imaging paradigms","volume":"40","author":"Sharma","year":"2020","journal-title":"Radiographics"},{"key":"2024050215121295700_b2","unstructured":"Food and Drug Administration\n          \n\u00a0Medical Device Reports of Breast Implant-Associated Anaplastic Large Cell Lymphoma 2019\n.. Available from:\nhttps:\/\/www.fda.gov\/medical-devices\/breast-implants\/medical-device- reports-breast-implant-associated-anaplastic-large-cell-lymphoma\n."},{"key":"2024050215121295700_b3","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1093\/asj\/sjy331","article-title":"2019 NCCN consensus guidelines on the diagnosis and treatment of breast implant-associated anaplastic large cell lymphoma (BIA-ALCL","volume":"39","author":"Clemens","year":"2019","journal-title":"Aesthet Surg J"},{"issue":"3S","key":"2024050215121295700_b4","doi-asserted-by":"crossref","first-page":"65S","DOI":"10.1097\/PRS.0000000000005571","article-title":"Patient registry and outcomes for breast implants and anaplastic large cell lymphoma etiology and epidemiology (profile): initial report of findings, 2012-2018","volume":"143","author":"McCarthy","year":"2019","journal-title":"Plast Reconstr Surg"},{"key":"2024050215121295700_b5","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1111\/bjh.17194","article-title":"Uk guidelines on the diagnosis and treatment of breast implant-associated anaplastic large cell lymphoma on behalf of the medicines and healthcare products regulatory agency plastic, reconstructive and aesthetic surgery expert Advisory group","volume":"192","author":"Turton","year":"2021","journal-title":"Br J Haematol"},{"key":"2024050215121295700_b6","doi-asserted-by":"crossref","first-page":"554,555","DOI":"10.1097\/00006534-199708000-00065","article-title":"Anaplastic T-cell lymphoma in proximity to a saline-filled breast implant","volume":"100","author":"Keech","year":"1997","journal-title":"Plast Reconstr Surg"},{"key":"2024050215121295700_b7","first-page":"421","volume-title":"WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues. 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