{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T02:50:52Z","timestamp":1787021452425,"version":"build-2736575974"},"reference-count":22,"publisher":"Oxford University Press (OUP)","issue":"1129","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,1,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>Multisystem inflammatory syndrome in children (MIS-C) is seen as a serious delayed complication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The aim of this study was to describe the most common imaging features of MIS-C associated with SARS-CoV-2.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A retrospective review was made of the medical records and radiological imaging studies of 47 children (26 male, 21 female) in the age range of 25 months\u201315 years who were diagnosed with MIS-C between August 2020 and March 2021. Chest radiographs were available for all 47 patients, thorax ultrasound for 6, chest CT for 4, abdominal ultrasound for 42, abdomen CT for 9, neck ultrasound for 4, neck CT for 2, brain CT for 1, and brain MRI for 3.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The most common finding on chest radiographs was perihilar\u2013peribronchial thickening (46%). The most common findings on abdominal ultrasonography were mesenteric inflammation (42%), and hepatosplenomegaly (38%, 28%). Lymphadenopathy was determined in four patients who underwent neck ultrasound, one of whom had deep neck infection on CT. One patient had restricted diffusion and T2 hyperintensity involving the corpus callosum splenium on brain MRI, and one patient had epididymitis related with MIS-C.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Pulmonary manifestations are uncommon in MIS-C. In the abdominal imaging, mesenteric inflammation, hepatosplenomegaly, periportal edema, ascites and bowel wall thickening are the most common findings.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Advances in knowledge:<\/jats:title>\n                    <jats:p>The imaging findings of MIS-C are non-specific and can mimic many other pathologies. Radiologists should be aware that these findings may indicate the correct diagnosis of MIS-C.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1259\/bjr.20210570","type":"journal-article","created":{"date-parts":[[2021,12,10]],"date-time":"2021-12-10T09:47:56Z","timestamp":1639129676000},"source":"Crossref","is-referenced-by-count":17,"title":["Multisystem inflammatory syndrome in children associated with SARS-CoV-2: extracardiac radiological findings"],"prefix":"10.1093","volume":"95","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2109-139X","authenticated-orcid":false,"given":"Berna","family":"Ucan","sequence":"first","affiliation":[{"name":"Department of Pediatric Radiology, Dr. Sami Ulus Gynecology, Obstetricsand Child Health and Diseases Training and Research Hospital , Ankara , Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seda","family":"Kaynak Sahap","sequence":"additional","affiliation":[{"name":"Department of Pediatric Radiology, Dr. Sami Ulus Gynecology, Obstetricsand Child Health and Diseases Training and Research Hospital , Ankara , Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hasibe Gokce","family":"Cinar","sequence":"additional","affiliation":[{"name":"Department of Pediatric Radiology, Dr. Sami Ulus Gynecology, Obstetricsand Child Health and Diseases Training and Research Hospital , Ankara , Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasemin","family":"Tasci Yildiz","sequence":"additional","affiliation":[{"name":"Department of Pediatric Radiology, Dr. Sami Ulus Gynecology, Obstetricsand Child Health and Diseases Training and Research Hospital , Ankara , Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cigdem","family":"Uner","sequence":"additional","affiliation":[{"name":"Department of Pediatric Radiology, Dr. Sami Ulus Gynecology, Obstetricsand Child Health and Diseases Training and Research Hospital , Ankara , Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meltem","family":"Polat","sequence":"additional","affiliation":[{"name":"Department of Pediatric Infectious Disease, Dr. Sami Ulus Gynecology, Obstetrics and Child Health and Diseases Training and Research Hospital , Ankara , Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Betul Emine","family":"Derinkuyu","sequence":"additional","affiliation":[{"name":"Department of Pediatric Radiology, Dr. Sami Ulus Gynecology, Obstetricsand Child Health and Diseases Training and Research Hospital , Ankara , Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2021,12,10]]},"reference":[{"key":"2024050310483662800_b1","unstructured":"Centers for Disease Control and Prevention (CDC) website.\n          \n\u00a0Health department-reported cases of multisystem inflammatory syndrome in children (MIS-C) in the United States\n.\n2021\n. Available from:\nwww.cdc.gov\/mis-c\/cases\/index.html\n."},{"key":"2024050310483662800_b2","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1016\/j.acra.2021.01.022","article-title":"Pathophysiology and imaging findings of COVID-19 infection: an Organ-system based review","volume":"28","author":"Capaccione","year":"2021","journal-title":"Acad Radiol"},{"key":"2024050310483662800_b3","doi-asserted-by":"crossref","first-page":"1607","DOI":"10.1016\/S0140-6736(20)31094-1","article-title":"Hyperinflammatory shock in children during COVID-19 pandemic","volume":"395","author":"Riphagen","year":"2020","journal-title":"The Lancet"},{"key":"2024050310483662800_b4","doi-asserted-by":"crossref","first-page":"1771","DOI":"10.1016\/S0140-6736(20)31103-X","article-title":"An outbreak of severe Kawasaki-like disease at the Italian epicentre of the SARS-CoV-2 epidemic: an observational cohort study","volume":"395","author":"Verdoni","year":"2020","journal-title":"The 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