{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T23:03:59Z","timestamp":1773875039961,"version":"3.50.1"},"reference-count":19,"publisher":"Oxford University Press (OUP)","issue":"1129","license":[{"start":{"date-parts":[[2021,11,4]],"date-time":"2021-11-04T00:00:00Z","timestamp":1635984000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,1,1]]},"abstract":"<jats:sec>\n                  <jats:title>Objective:<\/jats:title>\n                  <jats:p>Adrenal adenomas are frequently picked up incidentally on cross-sectional imaging and are known to have a classic imaging appearance on CT and MRI. However, not all adrenal adenomas have this typical radiologic appearance. Our aim is to present the radiological features of atypical adrenocortical adenomas with pathological correlation.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods:<\/jats:title>\n                  <jats:p>All the imaging from the pathologically proven adrenal adenoma cases in our hospital (Tallaght University Hospital, Dublin, Ireland) database (from 2004 to 2019) was reviewed. 8 out of 48 cases (16%) had an atypical radiological appearance and were selected for presentation.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results:<\/jats:title>\n                  <jats:p>Eight cases demonstrated atypical radiological features including heterogeneous density, incomplete washout on post-contrast imaging, the presence of macroscopic fat and calcification. Lipomatous metaplasia was present in two of the cases pathologically.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion:<\/jats:title>\n                  <jats:p>Adrenocortical adenomas are the most common adrenal mass encountered on CT, however, may not always have classic imaging features. Radiologists should be familiar with both the typical and atypical imaging manifestations of these benign adrenal lesions.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Advances in knowledge:<\/jats:title>\n                  <jats:p>This paper comprehensively describes the atypical features of adrenocortical adenomas with case examples and radiologic\u2013pathologic correlation. Guidelines and an approach to the work-up of adrenal lesions with atypical appearances are also provided.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1259\/bjr.20210642","type":"journal-article","created":{"date-parts":[[2021,11,4]],"date-time":"2021-11-04T18:45:10Z","timestamp":1636051510000},"source":"Crossref","is-referenced-by-count":6,"title":["Imaging features of atypical adrenocortical adenomas: a radiological-pathological correlation"],"prefix":"10.1093","volume":"95","author":[{"given":"Mary Louise","family":"Gargan","sequence":"first","affiliation":[{"name":"Tallaght University Hospital , Dublin , Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eimear","family":"Lee","sequence":"additional","affiliation":[{"name":"Tallaght University Hospital , Dublin , Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maeve","family":"O'Sullivan","sequence":"additional","affiliation":[{"name":"Tallaght University Hospital , Dublin , Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie","family":"Egan","sequence":"additional","affiliation":[{"name":"Tallaght University Hospital , Dublin , Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James","family":"Gibney","sequence":"additional","affiliation":[{"name":"Tallaght University Hospital , Dublin , Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen","family":"Crowther","sequence":"additional","affiliation":[{"name":"Tallaght University Hospital , Dublin , Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin","family":"Conlon","sequence":"additional","affiliation":[{"name":"Tallaght University Hospital, St. Vincent\u2019s University Hospital , Dublin , Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Feeney","sequence":"additional","affiliation":[{"name":"Tallaght University Hospital , Dublin , Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,11,4]]},"reference":[{"key":"2024050310483331500_b1","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1007\/BF03344099","article-title":"Prevalence of adrenal incidentaloma in a contemporary computerized tomography series","volume":"29","author":"Bovio","year":"2006","journal-title":"J Endocrinol Invest"},{"key":"2024050310483331500_b2","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1148\/radiographics.21.4.g01jl21995","article-title":"State-Of-The-Art adrenal imaging","volume":"21","author":"Mayo-Smith","year":"2001","journal-title":"Radiographics"},{"key":"2024050310483331500_b3","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1148\/rg.295095027","article-title":"Adrenal mass imaging with multidetector CT: pathologic conditions, pearls, and pitfalls","volume":"29","author":"Johnson","year":"2009","journal-title":"Radiographics"},{"key":"2024050310483331500_b4","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.ejrad.2007.11.041","article-title":"Differential diagnosis of incidentally detected adrenal masses revealed on routine abdominal CT","volume":"69","author":"Ctvrtl\u00edk","year":"2009","journal-title":"Eur J Radiol"},{"key":"2024050310483331500_b5","doi-asserted-by":"crossref","first-page":"531","DOI":"10.2214\/ajr.166.3.8623622","article-title":"Differentiation of adrenal adenomas from nonadenomas using CT attenuation values","volume":"166","author":"Korobkin","year":"1996","journal-title":"AJR Am J Roentgenol"},{"key":"2024050310483331500_b6","doi-asserted-by":"crossref","first-page":"1411","DOI":"10.2214\/ajr.175.5.1751411","article-title":"Delayed enhanced CT of lipid-poor adrenal adenomas","volume":"175","author":"Caoili","year":"2000","journal-title":"American Journal of Roentgenology"},{"key":"2024050310483331500_b7","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1148\/radiol.2342031876","article-title":"Adrenocortical carcinomas and adrenal pheochromocytomas: mass and enhancement loss evaluation at delayed contrast-enhanced CT","volume":"234","author":"Szolar","year":"2005","journal-title":"Radiology"},{"key":"2024050310483331500_b8","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1148\/radiol.12120110","article-title":"Evaluation of adrenal metastases from renal cell carcinoma and hepatocellular carcinoma: use of delayed contrast-enhanced CT","volume":"266","author":"Choi","year":"2013","journal-title":"Radiology"},{"key":"2024050310483331500_b9","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1007\/s00261-019-02215-9","article-title":"Adrenal cortical adenoma: current update, imaging features, atypical findings, and mimics","volume":"45","author":"Elbanan","year":"2020","journal-title":"Abdom Radiol"},{"key":"2024050310483331500_b10","doi-asserted-by":"crossref","first-page":"18","DOI":"10.37549\/AR2372","article-title":"MR imaging of adrenal lesions","volume":"46","author":"Kilcoyne","year":"2017","journal-title":"Appl Radiol"},{"key":"2024050310483331500_b11","doi-asserted-by":"crossref","first-page":"R65","DOI":"10.1530\/ERC-16-0564","article-title":"Lipomatous tumours in adrenal gland: who updates and clinical implications","volume":"24","author":"Lam","year":"2017","journal-title":"Endocr Relat Cancer"},{"key":"2024050310483331500_b12","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/S0344-0338(96)80132-4","article-title":"Adrenal cortical adenoma with extensive fat cell metaplasia","volume":"192","author":"Feldberg","year":"1996","journal-title":"Pathol Res Pract"},{"key":"2024050310483331500_b13","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/BF02932620","article-title":"Calcified adrenal masses","volume":"9","author":"Kenney","year":"1987","journal-title":"Urol Radiol"},{"key":"2024050310483331500_b14","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.2214\/AJR.16.17758","article-title":"Update on CT and MRI of adrenal nodules","volume":"208","author":"Schieda","year":"2017","journal-title":"AJR Am J Roentgenol"},{"key":"2024050310483331500_b15","unstructured":"Acsearch.acr.org\/docs\/69366\/Narrative (web guidelines) The American College of Radiology (ACR).\n          \n\u00a0Appropriateness criteria for adrenal mass evaluation\n.\n2021\n. Available from:\nhttps:\/\/www.acr.org\/Clinical-Resources\/ACR-Appropriateness-Criteria\n."},{"key":"2024050310483331500_b16","doi-asserted-by":"crossref","first-page":"1537","DOI":"10.1002\/cncr.20555","article-title":"Cystic adrenal neoplasms","volume":"101","author":"Erickson","year":"2004","journal-title":"Cancer"},{"key":"2024050310483331500_b17","doi-asserted-by":"crossref","first-page":"G1","DOI":"10.1530\/EJE-16-0467","article-title":"Management of adrenal incidentalomas: European Society of endocrinology clinical practice guideline in collaboration with the European network for the study of adrenal tumors","volume":"175","author":"Fassnacht","year":"2016","journal-title":"Eur J Endocrinol"},{"key":"2024050310483331500_b18","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1148\/radiol.11100569","article-title":"Characterization of adrenal masses by using FDG PET: a systematic review and meta-analysis of diagnostic test performance","volume":"259","author":"Boland","year":"2011","journal-title":"Radiology"},{"key":"2024050310483331500_b19","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1016\/j.ejrnm.2018.04.011","article-title":"Differentiation of adrenal incidentalomas by qualitative and quantitative analytical data obtained by 18F-FDG positron emission tomography\/computed tomography in cancer patients","volume":"49","author":"Mohamed","year":"2018","journal-title":"Egypt J Radiol Nucl Med"}],"container-title":["The British Journal of Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/bjr\/article-pdf\/95\/1129\/20210642\/57371454\/bjr.20210642.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bjr\/article-pdf\/95\/1129\/20210642\/57371454\/bjr.20210642.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,3]],"date-time":"2024-05-03T10:50:56Z","timestamp":1714733456000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bjr\/article\/doi\/10.1259\/bjr.20210642\/7451381"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,4]]},"references-count":19,"journal-issue":{"issue":"1129","published-online":{"date-parts":[[2021,11,4]]},"published-print":{"date-parts":[[2022,1,1]]}},"URL":"https:\/\/doi.org\/10.1259\/bjr.20210642","relation":{},"ISSN":["0007-1285","1748-880X"],"issn-type":[{"value":"0007-1285","type":"print"},{"value":"1748-880X","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2022,1,1]]},"published":{"date-parts":[[2021,11,4]]},"article-number":"20210642"}}