{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,15]],"date-time":"2026-03-15T10:47:25Z","timestamp":1773571645033,"version":"3.50.1"},"reference-count":25,"publisher":"Oxford University Press (OUP)","issue":"1133","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BJR"],"published-print":{"date-parts":[[2022,5,1]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>Late gadolinium enhancement with fixed short inversion time (LGE<jats:sub>short<\/jats:sub>) provides excellent tissue contrast with dark scar and bright blood pool and does not need prior myocardial nulling. We hypothesize better visibility of ischemic scars and equal visibility of non-ischemic LGE in LGE<jats:sub>short<\/jats:sub>compared to clinically established LGE (LGE<jats:sub>standard<\/jats:sub>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>LGE<jats:sub>short<\/jats:sub>and LGE<jats:sub>standard<\/jats:sub>were retrospectively evaluated in 179 patients (3043 segments) with suspected or known coronary artery disease by four blinded readers (reader A: most experienced - D: least experienced). The amount of ischemic and non-ischemic LGE as well as visibility (4: very good \u2013 1: poor) of ischemic LGE was visually assessed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>All readers detected more infarcted segments in LGE<jats:sub>short<\/jats:sub>compared to LGE<jats:sub>standard<\/jats:sub>(378 segments reported as infarcted; A:p = 0.5, B:p = 0.8, C,D:p = 0.03). Scar visibility was scored higher in LGE<jats:sub>short<\/jats:sub>by all readers (A,B:p = 0.03; C,D:p = 0.02), especially for subendocardial infarcts (A,B:p = 0.04, C,D:p = 0.02). Less experienced readers detected significantly more infarcted papillary muscles (C:p = 0.02, D:p = 0.03) in a shorter reading time in LGE<jats:sub>short<\/jats:sub>(C:p = 0.04, D:p = 0.02). Non-ischemic LGE was equally visible in both sequences (A:p = 0.9, B:p = 0.8, C,D:p = 0.6).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>LGE<jats:sub>short<\/jats:sub>detects more ischemic LGE with improved scar visibility compared to LGE<jats:sub>standard<\/jats:sub>, independent of experience level. The visibility of non-ischemic LGE is equivalent to LGE<jats:sub>standard<\/jats:sub>. Less experienced readers can diagnose ischemic and non-ischemic LGE faster in LGE<jats:sub>short<\/jats:sub>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Advances in knowledge:<\/jats:title><jats:p>LGE<jats:sub>short<\/jats:sub>with its maximal operational simplicity can be used for visualization of all types of fibrosis \u2013 ischemic and non-ischemic \u2013 instead of LGE<jats:sub>standard<\/jats:sub>, independent of experience level.<\/jats:p><\/jats:sec>","DOI":"10.1259\/bjr.20210966","type":"journal-article","created":{"date-parts":[[2022,2,23]],"date-time":"2022-02-23T16:52:47Z","timestamp":1645635167000},"source":"Crossref","is-referenced-by-count":1,"title":["Simplified image acquisition and detection of ischemic and non-ischemic myocardial fibrosis with fixed short inversion time magnetic resonance late gadolinium enhancement"],"prefix":"10.1093","volume":"95","author":[{"given":"Malgorzata","family":"Polacin","sequence":"first","affiliation":[{"name":"Institute of Diagnostic 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