{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T06:29:58Z","timestamp":1785306598000,"version":"3.55.0"},"reference-count":16,"publisher":"Oxford University Press (OUP)","issue":"1134","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,6,1]]},"abstract":"<jats:sec>\n                  <jats:title>Objectives:<\/jats:title>\n                  <jats:p>To evaluate interobserver variability for diagnosis of disease presence and extent of small bowel and colonic Crohn\u2019s disease using MR enterography (MRE)<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods:<\/jats:title>\n                  <jats:p>Data from the first 73 consecutive patients (mean age 32, 33F, 28 new diagnosis, 45 suspected relapse) recruited to a multicentre, prospective diagnostic accuracy trial evaluating MRE for small bowel Crohn\u2019s disease were each read independently by three (from a pool of 20) radiologists. Radiologists documented presence and segmental location of small bowel Crohn\u2019s disease and recorded morphological mural\/extramural parameters for involved segments. Per patient percentage agreement for disease presence and extent were calculated against an outcome-based construct reference standard (averaged between pairs of readers). Prevalence-adjusted bias-adjusted \u03ba (PABAK) was calculated.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results:<\/jats:title>\n                  <jats:p>Agreement for small bowel disease presence for new diagnosis\/relapsed patients was 68%(\u03ba = 0.36)\/ 78% (\u03ba = 0.56) and 43%(\u03ba = 0.14)\/ 53% for disease extent (\u03ba = 0.07), respectively. For disease presence, all three radiologists agreed correctly with the reference standard in 41\/59 (69%) of patients with small bowel involvement, and in 8\/14 (57%) cases of without small bowel disease. Agreement was highest for multisegment disease, greater than 5\u2009cm in length, with mural thickness&amp;gt;6\u2009mm, and increased mural T2 signal. Agreement for colonic disease presence was 61% (\u03ba = 0.21\u2009fair agreement) for new diagnosis\/ 60% (\u03ba = 0.20, slight agreement) for relapsed patients.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion:<\/jats:title>\n                  <jats:p>There is a reasonable agreement between radiologists for small bowel disease presence using MRE for newly diagnosed Crohn\u2019s disease, and patients with suspected relapse, respectively. Agreement is lower for disease extent.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Advances in knowledge:<\/jats:title>\n                  <jats:p>There is reasonable agreement between radiologists for small bowel disease presence using MRE for newly diagnosed (68%) Crohn\u2019s disease, and patients with suspected relapse (78%). Agreement is lower for disease extent (43% new diagnosis and 53% suspected relapse).<\/jats:p>\n               <\/jats:sec>","DOI":"10.1259\/bjr.20210995","type":"journal-article","created":{"date-parts":[[2022,2,23]],"date-time":"2022-02-23T16:54:18Z","timestamp":1645635258000},"source":"Crossref","is-referenced-by-count":26,"title":["Interobserver variation in the interpretation of magnetic resonance enterography in Crohn\u2019s disease"],"prefix":"10.1093","volume":"95","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6607-1117","authenticated-orcid":false,"given":"Gauraang","family":"Bhatnagar","sequence":"first","affiliation":[{"name":"Centre for Medical Imaging, Charles Bell House, University College London , London , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sue","family":"Mallett","sequence":"additional","affiliation":[{"name":"Centre for Medical Imaging, Charles Bell House, University College London , London , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Quinn","sequence":"additional","affiliation":[{"name":"Institute of Applied Health Research, NIHR Birmingham Biomedical Research Centre, College of Medical and Dental Sciences, University of Birmingham , Birmingham , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Beable","sequence":"additional","affiliation":[{"name":"Department of Radiology, Portsmouth Hospitals NHS Trust , Portsmouth , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helen","family":"Bungay","sequence":"additional","affiliation":[{"name":"Department of Radiology, Oxford University Hospitals NHS Trust , Oxford , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret","family":"Betts","sequence":"additional","affiliation":[{"name":"Department of Radiology, Oxford University Hospitals NHS Trust , Oxford , 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