{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T00:04:52Z","timestamp":1788825892160,"version":"build-2803163510"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"1137","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BJR"],"published-print":{"date-parts":[[2022,9,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To investigate the mid-term local treatment efficiency of ultrasound-guided percutaneous microwave ablation (MWA) for uterine fibroids (UFs) and the associated influencing factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>From July 2020 to October 2021, a total of 28 patients with 52 UFs who had undergone ultrasound-guided MWA were retrospectively included in this study. Pre-treatment clinical characteristics, conventional ultrasound and contrast-enhanced ultrasound (CEUS) features were analyzed to explore their correlation with volume reduction ratios (VRRs) of sufficient ablation (i.e. a VRR of at least 50% at the 3\u2009month follow-up). The patients were assessed at 1-, 3-, 6\u2009month follow-up after MWA treatment and the assessment included VRR, adverse events, uterine fibroid symptom (UFS) and quality of life (QoL) scores, and clinical symptoms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The procedures of percutaneous MWA for UFs were tolerated well and no major complications occurred in all patients. At the 1-, 3-, 6\u2009month follow-up, the median VRRs of UFs were 30.1%, 46.9%, and 65.8%, respectively. At the 3\u2009month follow-up, 44.4% of fibroids obtained sufficient ablation while the remaining 55.6% obtained partial ablation (i.e. a VRR of &lt;50%). Non-enhancing area during the early phase (i.e. within 30\u2009s after injecting contrast agent) on pre-treatment CEUS was present in 22.2% UFs, which was associated with sufficient ablation at the 3\u2009month follow-up (p &lt; 0.05). In addition, the relevant clinical symptoms of all patients were alleviated or removed. The UFS and QoL score after MWA decreased significantly in comparison with those after MWA (p = 0.04\u2009and p = 0.057, respectively), indicating a remarkable improvement of clinical symptom and QoL.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Ultrasound-guided MWA is an effective and safe method to treat patients with UFs. Non-enhancing area during the early phase on pretreatment CEUS is associated with mid-term local treatment efficiency, which might be used to predict treatment outcome.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Advances in knowledge:<\/jats:title>\n                    <jats:p>Non-enhancing area during the early phase on pretreatment CEUS is an important factor associated with mid-term local treatment efficiency. This is the first study finding that CEUS feature can be used as a marker for the prediction of mid-term local treatment response.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1259\/bjr.20220039","type":"journal-article","created":{"date-parts":[[2022,6,28]],"date-time":"2022-06-28T04:54:44Z","timestamp":1656392084000},"source":"Crossref","is-referenced-by-count":11,"title":["Ultrasound-guided percutaneous microwave ablation for uterine fibroids: mid-term local treatment efficiency and associated influencing factors"],"prefix":"10.1093","volume":"95","author":[{"given":"Qiu-Yan","family":"Li","sequence":"first","affiliation":[{"name":"School of Medicine, Anhui University of Science and Technology, Huainan Anhui, China"},{"name":"Department of Medical Ultrasound, Shanghai Tenth People\u2019s Hospital, Shanghai, China"},{"name":"Department of Medical Ultrasound, Center of Minimally Invasive Treatment for Tumor, Shanghai Tenth People\u2019s Hospital, Ultrasound Research and Education Institute, Clinical Research Center for Interventional Medicine, School of Medicine, Tongji University, Shanghai, China"},{"name":"Shanghai Engineering Research Center of Ultrasound Diagnosis and Treatment; National Clinical Research Center for Interventional Medicine, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-Long","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Medical Ultrasound, Center of Minimally Invasive Treatment for Tumor, Shanghai Tenth People\u2019s Hospital, Ultrasound Research and Education Institute, Clinical Research Center for Interventional Medicine, School of Medicine, Tongji University, Shanghai, China"},{"name":"Shanghai Engineering Research Center of Ultrasound Diagnosis and Treatment; National Clinical Research Center for Interventional Medicine, Shanghai, China"},{"name":"Department of Ultrasound, Zhongshan Hospital, Fudan University, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Er-Ya","family":"Deng","sequence":"additional","affiliation":[{"name":"School of Medicine, Anhui University of Science and Technology, Huainan Anhui, China"},{"name":"Department of Medical Ultrasound, Shanghai Tenth People\u2019s Hospital, Shanghai, China"},{"name":"Department of Medical Ultrasound, Center of Minimally Invasive Treatment for Tumor, Shanghai Tenth People\u2019s Hospital, Ultrasound Research and Education Institute, Clinical Research Center for Interventional Medicine, School of Medicine, Tongji University, Shanghai, China"},{"name":"Shanghai Engineering Research Center of Ultrasound Diagnosis and Treatment; National Clinical Research Center for Interventional Medicine, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Song-Yuan","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Medical Ultrasound, Center of Minimally Invasive Treatment for Tumor, Shanghai Tenth People\u2019s Hospital, Ultrasound Research and Education Institute, Clinical Research Center for Interventional Medicine, School of Medicine, Tongji University, Shanghai, China"},{"name":"Shanghai Engineering Research Center of Ultrasound Diagnosis and Treatment; National Clinical Research Center for Interventional Medicine, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li-Ping","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Medical Ultrasound, Center of Minimally Invasive Treatment for Tumor, Shanghai Tenth People\u2019s Hospital, Ultrasound Research and Education Institute, Clinical Research Center for Interventional Medicine, School of Medicine, Tongji University, Shanghai, China"},{"name":"Shanghai Engineering Research Center of Ultrasound Diagnosis and Treatment; National Clinical Research Center for Interventional Medicine, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui-Li","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Medical Ultrasound, Center of Minimally Invasive Treatment for Tumor, Shanghai Tenth People\u2019s Hospital, Ultrasound Research and Education Institute, Clinical Research Center for Interventional Medicine, School of Medicine, Tongji University, Shanghai, China"},{"name":"Shanghai Engineering Research Center of Ultrasound Diagnosis and Treatment; National Clinical Research Center for Interventional Medicine, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing-E","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Medical Ultrasound, Center of Minimally Invasive Treatment for Tumor, Shanghai Tenth People\u2019s Hospital, Ultrasound Research and Education Institute, Clinical Research Center for Interventional Medicine, School of Medicine, Tongji University, Shanghai, China"},{"name":"Shanghai Engineering Research Center of Ultrasound Diagnosis and Treatment; National Clinical Research Center for Interventional Medicine, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia-Xin","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Medical Ultrasound, Center of Minimally Invasive Treatment for Tumor, Shanghai Tenth People\u2019s Hospital, Ultrasound Research and Education Institute, Clinical Research Center for Interventional Medicine, School of Medicine, Tongji University, Shanghai, China"},{"name":"Shanghai Engineering Research Center of Ultrasound Diagnosis and Treatment; National Clinical Research Center for Interventional Medicine, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui-Xiong","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Ultrasound, Zhongshan Hospital, Fudan University, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","reference":[{"key":"b1","doi-asserted-by":"publisher","DOI":"10.1080\/02656736.2021.1973585"},{"key":"b2","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2016.43"},{"key":"b3","doi-asserted-by":"publisher","DOI":"10.1080\/02656736.2021.1889697"},{"key":"b4","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.14640"},{"key":"b5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2021.06.020"},{"key":"b6","doi-asserted-by":"publisher","DOI":"10.3109\/02656736.2011.562872"},{"key":"b7","doi-asserted-by":"publisher","DOI":"10.2147\/IJWH.S15710"},{"key":"b8","doi-asserted-by":"publisher","DOI":"10.3109\/02656736.2015.1014869"},{"key":"b9","doi-asserted-by":"publisher","DOI":"10.3109\/02656736.2016.1164905"},{"key":"b10","doi-asserted-by":"publisher","DOI":"10.3109\/02656736.2015.1014433"},{"key":"b11","doi-asserted-by":"publisher","DOI":"10.1080\/13645706.2019.1668417"},{"key":"b12","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2018.06.014"},{"key":"b13","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultrasmedbio.2020.09.016"},{"key":"b14","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/2360107"},{"key":"b15","doi-asserted-by":"publisher","DOI":"10.1002\/jum.14838"},{"key":"b16","first-page":"3095","volume":"123","author":"Zhang X-L","year":"2010","journal-title":"Chin Med J (Engl)"},{"key":"b17","first-page":"90","volume":"15","author":"Zhang J","year":"2018","journal-title":"Chin J Med Ultrasound (Electronic Edition)"},{"key":"b18","first-page":"290","volume":"99","author":"Spies JB","year":"2002","journal-title":"Obstet Gynecol"},{"key":"b19","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2009.05.043"},{"key":"b20","doi-asserted-by":"publisher","DOI":"10.1016\/j.acra.2018.01.022"},{"key":"b21","doi-asserted-by":"publisher","DOI":"10.1089\/lap.2019.0550"},{"key":"b22","doi-asserted-by":"publisher","DOI":"10.1080\/02656736.2018.1511837"},{"key":"b23","first-page":"869","volume":"31","author":"Cheng H","year":"2015","journal-title":"Pak J Med Sci"},{"key":"b24","doi-asserted-by":"publisher","DOI":"10.3892\/etm.2015.2879"},{"key":"b25","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2014.11.041"},{"key":"b26","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultras.2015.01.005"},{"key":"b27","doi-asserted-by":"publisher","DOI":"10.1002\/jum.15495"},{"key":"b28","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2006.11.039"},{"key":"b29","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultrasmedbio.2018.03.030"},{"key":"b30","doi-asserted-by":"publisher","DOI":"10.1080\/02656736.2018.1564843"}],"container-title":["The British Journal of Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.birpublications.org\/doi\/pdf\/10.1259\/bjr.20220039","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,12]],"date-time":"2024-01-12T11:43:55Z","timestamp":1705059835000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bjr\/article\/7451343"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,1]]},"references-count":30,"journal-issue":{"issue":"1137","published-print":{"date-parts":[[2022,9,1]]}},"alternative-id":["10.1259\/bjr.20220039"],"URL":"https:\/\/doi.org\/10.1259\/bjr.20220039","relation":{},"ISSN":["0007-1285","1748-880X"],"issn-type":[{"value":"0007-1285","type":"print"},{"value":"1748-880X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,9,1]]},"article-number":"20220039"}}