{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T23:39:42Z","timestamp":1784763582515,"version":"3.55.0"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"1149","license":[{"start":{"date-parts":[[2023,7,26]],"date-time":"2023-07-26T00:00:00Z","timestamp":1690329600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,8,1]]},"abstract":"<jats:sec>\n                  <jats:title>Objective:<\/jats:title>\n                  <jats:p>To assess the cumulated exposure to radiation due to imaging in Hodgkin (HL) and diffuse large B-cell (DLBCL) lymphoma patients who were not submitted to radiotherapy.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods:<\/jats:title>\n                  <jats:p>The study population included 51 and 83 adult patients with HL and DLBCL, with a follow-up duration &amp;gt;1\u2009year. The cumulated exposure was expressed using patient-specific data as cumulated effective dose (CED).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results:<\/jats:title>\n                  <jats:p>Fifty-one HL patients (median age 47 years) were followed for a median of 3.5 years. The median total CED per subject was 104\u2009mSv. CT and PET\/CT examinations accounted for 75 and 25% of the total CED, respectively. 26 patients (49%) had a total CED \u2265 100\u2009mSv and the maximum CED was 302\u2009mSv.<\/jats:p>\n                  <jats:p>Eighty-three DLBCL patients (median age 66 years) were followed for a median of 3.7 years. The median total CED per subject over the study period was 134 mSv. CT and PET\/CT for 86% and 13% of the total CED, respectively. 56 patients (67%) had a total CED \u2265100 mSv. The maximum CED was 557 mSv.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion:<\/jats:title>\n                  <jats:p>Our study demonstrated the large number of imaging procedures performed for patients with lymphoma. Overall, 61% of the patients accrued a CED \u2265 100 mSv. Imaging policies were only in a partial agreement with current international guidelines.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Advances in knowledge:<\/jats:title>\n                  <jats:p>The cumulated exposure radiation exposure may be of concern in HL patients and the contribution of CT procedures to the total CED is significant. The standardisation of clinical guidelines for managing patients with lymphoma is warranted.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1259\/bjr.20230106","type":"journal-article","created":{"date-parts":[[2023,7,26]],"date-time":"2023-07-26T11:55:36Z","timestamp":1690372536000},"source":"Crossref","is-referenced-by-count":1,"title":["Cumulative radiation exposure from radiological imaging in patients with Hodgkin and diffuse large b-cell lymphoma not submitted to radiotherapy"],"prefix":"10.1093","volume":"96","author":[{"given":"Marco","family":"Brambilla","sequence":"first","affiliation":[{"name":"Medical Physics Department, University Hospital \u201cMaggiore della Carit\u00e0\u201d , Novara, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberta","family":"Matheoud","sequence":"additional","affiliation":[{"name":"Medical Physics Department, University Hospital \u201cMaggiore della Carit\u00e0\u201d , Novara, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gloria","family":"Margiotta-Casaluci","sequence":"additional","affiliation":[{"name":"Division of Hematology, Department of Translational Medicine, University of Eastern Piedmont , Novara, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Cannillo","sequence":"additional","affiliation":[{"name":"Medical Physics Department, University Hospital \u201cMaggiore della Carit\u00e0\u201d , Novara, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"D'Alessio","sequence":"additional","affiliation":[{"name":"Medical Physics Department, University Hospital \u201cMaggiore della Carit\u00e0\u201d , Novara, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiara","family":"Siciliano","sequence":"additional","affiliation":[{"name":"Radiology Department, University Hospital \u201cMaggiore della Carit\u00e0\u201d , Hodgkin, 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