{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T22:11:46Z","timestamp":1774303906363,"version":"3.50.1"},"reference-count":34,"publisher":"Oxford University Press (OUP)","issue":"1150","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,10,1]]},"abstract":"<jats:sec>\n                  <jats:title>Objective:<\/jats:title>\n                  <jats:p>To validate selection criteria for sublobar resection in patients with lung cancer with respect to recurrence, and to investigate predictors for recurrence in patients for whom the criteria are not suitable.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods:<\/jats:title>\n                  <jats:p>Patients who underwent sublobar resection for lung cancer between July 2010 and December 2018 were retrospectively included. The criteria for curative sublobar resection were consolidation-to-tumor ratio \u22640.50\u2009and size \u22643.0\u2009cm in tumors with a ground-glass opacity (GGO) component (GGO group), and size of \u22642.0\u2009cm and volume doubling time \u2265400 days in solid tumors (solid group). Cox regression was used to identify predictors for time-to-recurrence (TTR) in tumors outside of these criteria (non-curative group).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results:<\/jats:title>\n                  <jats:p>Out of 530 patients, 353 were classified into the GGO group and 177 into the solid group. In the GGO group, the 2-year recurrence rates in curative and non-curative groups were 2.1 and 7.7%, respectively (p = 0.054). In the solid group, the 2-year recurrence rates in curative and non-curative groups were 0.0 and 28.6%, respectively (p = 0.03). Predictors of 2-year TTR after non-curative sublobar resection were pathological nodal metastasis (hazard ratio [HR], 6.63; p = 0.02) and lymphovascular invasion (LVI; HR, 3.28; p = 0.03) in the GGO group, and LVI (HR, 4.37; p &amp;lt; 0.001) and fibrosis (HR, 3.18; p = 0.006) in the solid group.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion:<\/jats:title>\n                  <jats:p>The current patient selection criteria for sublobar resection are satisfactory. LVI was a predictor for recurrence after non-curative resection.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Advances in knowledge:<\/jats:title>\n                  <jats:p>This result supports selection criteria of patients for sublobar resection. LVI may help predict recurrence after non-curative sublobar resection.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1259\/bjr.20230143","type":"journal-article","created":{"date-parts":[[2023,8,10]],"date-time":"2023-08-10T15:22:57Z","timestamp":1691680977000},"source":"Crossref","is-referenced-by-count":2,"title":["Sublobar resection in non-small cell lung cancer: patient selection criteria and risk factors for recurrence"],"prefix":"10.1093","volume":"96","author":[{"given":"Sohee","family":"Park","sequence":"first","affiliation":[{"name":"Department of Radiology, Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center , Seoul, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sang Min","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Radiology, Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center , Seoul, South 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