{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T21:21:03Z","timestamp":1790716863252,"version":"4.1.0"},"reference-count":37,"publisher":"Oxford University Press (OUP)","issue":"1152","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,12,1]]},"abstract":"<jats:sec>\n                  <jats:title>Objective:<\/jats:title>\n                  <jats:p>Vascular and bleeding complications after transcatheter aortic valve implantation (TAVI) are common and lead to increased morbidity and mortality. Analysis of plaque at the arterial access site may improve prediction of complications.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods:<\/jats:title>\n                  <jats:p>We investigated the association between demographic and procedural risk factors for Valve Academic Research Consortium (VARC-3) vascular complications in patients undergoing transfemoral TAVI with use of a vascular closure device (ProGlide\u00ae or MANTA\u00ae) in this retrospective cohort study. The ability of pre-procedure femoral CT angiography to predict complications was investigated including a novel method of quantifying plaque composition of the common femoral artery using plaque maps created with patient specific X-ray attenuation cut-offs.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results:<\/jats:title>\n                  <jats:p>23 vascular complications occurred in the 299 patients in the study group (7.7%). There were no demographic risk factors associated with vascular complications and no statistical difference between use of closure device (ProGlide\u00aevs MANTA\u00ae) and vascular complications. Vascular complications after TAVI were associated with sheath size (OR 1.36, 95%\u2009CI 1.08\u20131.76, P 0.01) and strongly associated with CT-derived necrotic core volume in the common femoral artery of the procedural side (OR 17.49, 95%\u2009CI 1.21\u2013226.60, P 0.03).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion:<\/jats:title>\n                  <jats:p>Plaque map analysis of the common femoral artery by CT angiography reveals patients with greater necrotic core are at increased risk of VARC-3 vascular complications.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Advances in knowledge:<\/jats:title>\n                  <jats:p>The novel measurement of necrotic core volume in the common femoral artery on the procedural side by CT analysis was associated with post-TAVI vascular complications, which can be used to highlight increased risk.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1259\/bjr.20230296","type":"journal-article","created":{"date-parts":[[2023,9,25]],"date-time":"2023-09-25T13:29:00Z","timestamp":1695648540000},"source":"Crossref","is-referenced-by-count":1,"title":["Computed tomography defined femoral artery plaque composition predicts vascular complications during transcatheter aortic valve implantation"],"prefix":"10.1093","volume":"96","author":[{"given":"Elliott J","family":"Carande","sequence":"first","affiliation":[{"name":"Cwm Taff Morgannwg University Health Board, Princess of Wales Hospital, Coity Road , Bridgend, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tarik S","family":"Salim","sequence":"additional","affiliation":[{"name":"Swansea Bay University Health Board, Morriston Hospital , Swansea, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Chase","sequence":"additional","affiliation":[{"name":"Swansea Bay University Health Board, Morriston Hospital , Swansea, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baskar","family":"Sekar","sequence":"additional","affiliation":[{"name":"Swansea Bay University Health Board, Morriston Hospital , Swansea, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omar","family":"Aldalati","sequence":"additional","affiliation":[{"name":"Swansea Bay University Health Board, Morriston Hospital , Swansea, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Hailan","sequence":"additional","affiliation":[{"name":"Swansea Bay University Health Board, Morriston Hospital , Swansea, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayush","family":"Khurana","sequence":"additional","affiliation":[{"name":"Swansea Bay University Health Board, Morriston Hospital , Swansea, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dave","family":"Smith","sequence":"additional","affiliation":[{"name":"Swansea Bay University Health Board, Morriston Hospital , Swansea, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel Rhys","family":"Obaid","sequence":"additional","affiliation":[{"name":"Swansea Bay University Health Board, Morriston Hospital , Swansea, United Kingdom"},{"name":"Swansea University Medical School , Swansea, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,10,24]]},"reference":[{"key":"2024010408222248500_b1","doi-asserted-by":"crossref","first-page":"1972","DOI":"10.1016\/j.jacc.2014.02.556","article-title":"Transcatheter aortic valve replacement using a self-expanding Bioprosthesis in patients with severe aortic stenosis at extreme risk for surgery","volume":"63","author":"Popma","year":"2014","journal-title":"J Am Coll Cardiol"},{"key":"2024010408222248500_b2","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1056\/NEJMc1408396","article-title":"Transcatheter aortic-valve replacement with a self-expanding Prosthesis","volume":"371","author":"Adams","year":"2014","journal-title":"N Engl J Med"},{"key":"2024010408222248500_b3","doi-asserted-by":"crossref","first-page":"2438","DOI":"10.1016\/j.jacc.2014.02.537","article-title":"2014 AHA\/ACC guideline for the management of patients with valvular heart disease: executive summary: a report of the American college of cardiology\/American heart Association task force on practice guidelines","volume":"63","author":"Nishimura","year":"2014","journal-title":"J Am Coll Cardiol"},{"key":"2024010408222248500_b4","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1056\/NEJMoa1514616","article-title":"Transcatheter or surgical aortic-valve replacement in intermediate-risk patients","volume":"374","author":"Leon","year":"2016","journal-title":"N Engl J Med"},{"key":"2024010408222248500_b5","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1056\/NEJMoa1700456","article-title":"Surgical or Transcatheter aortic-valve replacement in intermediate-risk patients","volume":"376","author":"Reardon","year":"2017","journal-title":"N Engl J Med"},{"key":"2024010408222248500_b6","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1016\/j.jcin.2011.03.019","article-title":"Transfemoral aortic valve implantation: new criteria to predict vascular complications","volume":"4","author":"Hayashida","year":"2011","journal-title":"JACC Cardiovasc Interv"},{"key":"2024010408222248500_b7","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1016\/j.jacc.2009.12.014","article-title":"Transcatheter aortic valve implantation for the treatment of severe symptomatic aortic stenosis in patients at very high or prohibitive surgical risk","volume":"55","author":"Rod\u00e9s-Cabau","year":"2010","journal-title":"J Am Coll Cardiol"},{"key":"2024010408222248500_b8","doi-asserted-by":"crossref","first-page":"673","DOI":"10.4244\/EIJV5I6A111","article-title":"Vascular complications with Transcatheter aortic valve implantation using the 18 FR Medtronic Corevalve system: the Rotterdam experience","volume":"5","author":"Van Mieghem","year":"2010","journal-title":"EuroIntervention"},{"key":"2024010408222248500_b9","doi-asserted-by":"crossref","first-page":"666","DOI":"10.4244\/EIJV5I6A110","article-title":"Vascular complications of Transfemoral aortic valve implantation with the Edwards SAPIEN Prosthesis: incidence and impact on outcome","volume":"5","author":"Ducrocq","year":"2010","journal-title":"EuroIntervention"},{"key":"2024010408222248500_b10","doi-asserted-by":"crossref","first-page":"659","DOI":"10.4244\/EIJV5I6A109","article-title":"Thirty-day outcome and vascular complications after Transarterial aortic valve implantation using both Edwards Sapien and Medtronic Corevalve Bioprostheses in a mixed population","volume":"5","author":"Tchetche","year":"2010","journal-title":"EuroIntervention"},{"key":"2024010408222248500_b11","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1007\/s00059-009-3252-3","article-title":"Vascular access site complications after percutaneous Transfemoral aortic valve implantation","volume":"34","author":"Kahlert","year":"2009","journal-title":"Herz"},{"key":"2024010408222248500_b12","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.1016\/j.amjcard.2012.06.042","article-title":"Incidence, predictors, and implications of access site complications with Transfemoral Transcatheter aortic valve implantation","volume":"110","author":"Van Mieghem","year":"2012","journal-title":"Am J Cardiol"},{"key":"2024010408222248500_b13","doi-asserted-by":"crossref","first-page":"2544","DOI":"10.1161\/CIRCULATIONAHA.107.698977","article-title":"Increased mortality, postoperative morbidity, and cost after red blood cell transfusion in patients having cardiac surgery","volume":"116","author":"Murphy","year":"2007","journal-title":"Circulation"},{"key":"2024010408222248500_b14","doi-asserted-by":"crossref","first-page":"2605","DOI":"10.1016\/j.jacc.2014.08.052","article-title":"Incidence, predictors, and Prognostic impact of late bleeding complications after Transcatheter aortic valve replacement","volume":"64","author":"G\u00e9n\u00e9reux","year":"2014","journal-title":"Journal of the American College of Cardiology"},{"key":"2024010408222248500_b15","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1016\/j.jacc.2013.10.058","article-title":"Bleeding complications after surgical aortic valve replacement compared with Transcatheter aortic valve replacement: insights from the PARTNER I trial (placement of aortic Transcatheter valve)","volume":"63","author":"G\u00e9n\u00e9reux","year":"2014","journal-title":"J Am Coll Cardiol"},{"key":"2024010408222248500_b16","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1007\/s11239-012-0842-3","article-title":"Transcatheter aortic valve implantation and bleeding: incidence, predictors and prognosis","volume":"35","author":"Pilgrim","year":"2013","journal-title":"J Thromb Thrombolysis"},{"key":"2024010408222248500_b17","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1136\/heartjnl-2012-303095","article-title":"Incidence, predictors and impact of bleeding after Transcatheter aortic valve implantation using the balloon-expandable Edwards Prosthesis","volume":"99","author":"Borz","year":"2013","journal-title":"Heart"},{"key":"2024010408222248500_b18","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/j.ahj.2012.07.003","article-title":"Adverse impact of bleeding and transfusion on the outcome post-Transcatheter aortic valve implantation: insights from the pooled-Rotterdam-Milano-Toulouse in collaboration plus (PRAGMATIC plus) initiative","volume":"164","author":"Tchetche","year":"2012","journal-title":"Am Heart J"},{"key":"2024010408222248500_b19","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.jtcvs.2012.09.002","article-title":"Updated standardized Endpoint definitions for Transcatheter aortic valve implantation: the valve academic research Consortium-2 consensus document","volume":"145","author":"Kappetein","year":"2013","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2024010408222248500_b20","doi-asserted-by":"crossref","first-page":"2717","DOI":"10.1016\/j.jacc.2021.02.038","article-title":"Valve academic research consortium 3: updated Endpoint definitions for aortic valve clinical research","volume":"77","author":"G\u00e9n\u00e9reux","year":"2021","journal-title":"Journal of the American College of Cardiology"},{"key":"2024010408222248500_b21","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1016\/j.jacc.2012.07.003","article-title":"Vascular complications after Transcatheter aortic valve replacement: insights from the PARTNER (placement of aortic Transcatheter valve) trial","volume":"60","author":"G\u00e9n\u00e9reux","year":"2012","journal-title":"J Am Coll Cardiol"},{"key":"2024010408222248500_b22","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.amjcard.2019.03.043","article-title":"Computed Tomographic angiography-derived risk factors for vascular complications in percutaneous Transfemoral Transcatheter aortic valve implantation","volume":"124","author":"Urbach","year":"2019","journal-title":"The American Journal of Cardiology"},{"key":"2024010408222248500_b23","article-title":"The Iliofemoral Tortuosity score predicts access and bleeding complications during Transfemoral Transcatheter aortic valve replacement: Datadata from the Vienna Cardio Thoracic aOrtic valve registrY (VICTORY)","volume":"51","author":"Mach","year":"2021","journal-title":"Eur J Clin Invest"},{"key":"2024010408222248500_b24","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.avsg.2017.06.137","article-title":"A novel iliac morphology score predicts procedural mortality and major vascular complications in Transfemoral aortic valve replacement","volume":"46","author":"Blakeslee-Carter","year":"2018","journal-title":"Ann Vasc Surg"},{"key":"2024010408222248500_b25","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1161\/CIRCIMAGING.112.000250","article-title":"Atherosclerotic plaque composition and classification identified by coronary computed tomography: assessment of computed tomography-generated plaque maps compared with virtual histology Intravascular ultrasound and histology","volume":"6","author":"Obaid","year":"2013","journal-title":"Circ Cardiovasc Imaging"},{"key":"2024010408222248500_b26","article-title":"Identification of vulnerable carotid plaque with histologically validated CT-derived plaque maps","volume":"96","author":"Obaid","year":"2023","journal-title":"Br J Radiol"},{"key":"2024010408222248500_b27","first-page":"S138","volume-title":"Cardiovascular Diagnosis and Therapy","author":"Daye","year":"2018"},{"key":"2024010408222248500_b28","doi-asserted-by":"crossref","first-page":"2157","DOI":"10.1161\/01.CIR.92.8.2157","article-title":"Coronary artery calcium area by electron-beam computed tomography and coronary Atherosclerotic plaque area. A histopathologic correlative study","volume":"92","author":"Rumberger","year":"1995","journal-title":"Circulation"},{"key":"2024010408222248500_b29","doi-asserted-by":"crossref","first-page":"1276","DOI":"10.1056\/NEJM199705013361802","article-title":"Coronary risk factors and plaque morphology in men with coronary disease who died suddenly","volume":"336","author":"Burke","year":"1997","journal-title":"N Engl J Med"},{"key":"2024010408222248500_b30","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1016\/j.jacc.2007.04.086","article-title":"Frequency and distribution of thin-cap Fibroatheroma and ruptured plaques in human coronary arteries. A pathologic study","volume":"50","author":"Cheruvu","year":"2007","journal-title":"J Am Coll Cardiol"},{"key":"2024010408222248500_b31","doi-asserted-by":"crossref","first-page":"5055","DOI":"10.1016\/j.actbio.2014.09.001","article-title":"Material properties of components in human carotid Atherosclerotic plaques: A Uniaxial extension study","volume":"10","author":"Teng","year":"2014","journal-title":"Acta Biomater"},{"key":"2024010408222248500_b32","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.clinimag.2023.06.009","article-title":"Characteristics of conventional high-risk coronary plaques and a novel CT defined thin-cap Fibroatheroma in patients undergoing CCTA with stable chest pain","volume":"101","author":"Salem","year":"2023","journal-title":"Clin Imaging"},{"key":"2024010408222248500_b33","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1016\/j.carrev.2020.01.007","article-title":"Incidence, prognosis and predictors of major vascular complications and percutaneous closure device failure following contemporary percutaneous Transfemoral Transcatheter aortic valve replacement","volume":"21","author":"Batchelor","year":"2020","journal-title":"Cardiovasc Revasc Med"},{"key":"2024010408222248500_b34","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/s42155-018-0026-0","article-title":"Access site complications after Transfemoral aortic valve implantation - a comparison of Manta and Proglide","volume":"1","author":"Hoffmann","year":"2018","journal-title":"CVIR Endovasc"},{"key":"2024010408222248500_b35","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.ijcard.2018.04.065","article-title":"MANTA versus Proglide vascular closure devices in Transfemoral Transcatheter aortic valve implantation","volume":"263","author":"Biancari","year":"2018","journal-title":"Int J Cardiol"},{"key":"2024010408222248500_b36","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1161\/CIRCULATIONAHA.121.057856","article-title":"Comparison of a pure plug-based versus a primary Suture-based vascular closure device strategy for Transfemoral Transcatheter aortic valve replacement: the CHOICE-CLOSURE randomized clinical trial","volume":"145","author":"Abdel-Wahab","year":"2022","journal-title":"Circulation"},{"key":"2024010408222248500_b37","doi-asserted-by":"crossref","DOI":"10.1155\/2015\/572681","article-title":"Changes of the eSheath outer dimensions used for Transfemoral Transcatheter aortic valve replacement","volume":"2015","author":"Koehler","year":"2015","journal-title":"Biomed Res Int"}],"container-title":["The British Journal of Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/bjr\/article-pdf\/96\/1152\/20230296\/55011955\/bjr.20230296.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bjr\/article-pdf\/96\/1152\/20230296\/55011955\/bjr.20230296.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,12]],"date-time":"2024-01-12T16:46:34Z","timestamp":1705077994000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bjr\/article\/7499052"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10,24]]},"references-count":37,"journal-issue":{"issue":"1152","published-online":{"date-parts":[[2023,10,24]]},"published-print":{"date-parts":[[2023,12,1]]}},"URL":"https:\/\/doi.org\/10.1259\/bjr.20230296","relation":{},"ISSN":["0007-1285","1748-880X"],"issn-type":[{"value":"0007-1285","type":"print"},{"value":"1748-880X","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2023,12,1]]},"published":{"date-parts":[[2023,10,24]]},"article-number":"20230296"}}