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Here, we present the case of a retropositive patient with constitutional symptoms, where whole-body positron emission tomography\/CT scan revealed intense 18F-fludeoxyglucose uptake in bulky adrenal glands, and subsequent positron emission tomography-guided biopsy helped in establishing the diagnosis of adrenal histoplasmosis.<\/jats:p>","DOI":"10.1259\/bjrcr.20150451","type":"journal-article","created":{"date-parts":[[2016,2,12]],"date-time":"2016-02-12T13:53:47Z","timestamp":1455285227000},"source":"Crossref","is-referenced-by-count":1,"title":["18F-FDG PET\/CT imaging and PET-guided biopsy in evaluation and treatment decision in adrenal histoplasmosis"],"prefix":"10.1093","volume":"2","author":[{"given":"Renjith Radhakrishnan","family":"Kalathoorakath","sequence":"first","affiliation":[{"name":"Department of Nuclear Medicine, PGIMER , Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aman","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, PGIMER , Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashwani","family":"Sood","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, PGIMER , Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uma","family":"Nahar","sequence":"additional","affiliation":[{"name":"Department of Histopathology, PGIMER , Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arun Kumar Reddy","family":"Gorla","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, PGIMER , Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bhagwant Rai","family":"Mittal","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, PGIMER , Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2016,2,24]]},"reference":[{"key":"2024090310355353100_bib1","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.mmcr.2013.04.003","article-title":"A rare presentation of progressive disseminated histoplasmosis in an immunocompetent patient from a non-endemic region","volume":"2","author":"Subbalaxmi","year":"2013","journal-title":"Med Mycol Case Rep"},{"key":"2024090310355353100_bib2","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1002\/dc.21416","article-title":"Bilateral adrenal histoplasmosis in immunocompetent patients","volume":"39","author":"Rana","year":"2011","journal-title":"Diagn Cytopathol"},{"key":"2024090310355353100_bib3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2012\/268123","article-title":"Histoplasma virulence and host responses","volume":"2012","author":"Mihu","year":"2012","journal-title":"Int J Microbiol"},{"key":"2024090310355353100_bib4","first-page":"54","article-title":"Adrenal histoplasmosis: unusual presentations","volume":"60","author":"Bhansali","year":"2012","journal-title":"J Assoc Physicians India"},{"key":"2024090310355353100_bib5","first-page":"920","article-title":"Adrenal histoplasmosis: a case series and review of the literature","volume":"42","author":"Larbcharoensub","year":"2011","journal-title":"Southeast Asian J Trop Med Public Health"},{"key":"2024090310355353100_bib6","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1111\/j.1754-9485.2012.02435.x","article-title":"Bilateral adrenal lesions","volume":"56","author":"Gupta","year":"2012","journal-title":"J Med Imaging Radiat Oncol"},{"key":"2024090310355353100_bib7","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1016\/j.eururo.2008.09.005","article-title":"Clinically inapparent bilateral adrenal masses due to histoplasmosis","volume":"55","author":"Narang","year":"2009","journal-title":"Eur Urol"},{"key":"2024090310355353100_bib8","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1016\/j.clinimag.2013.02.011","article-title":"18F-fluorodeoxyglucose positron emission tomography for the initial evaluation and monitoring of therapeutic response in bilateral adrenal histoplasmosis","volume":"37","author":"Tsai","year":"2013","journal-title":"Clin Imaging"},{"key":"2024090310355353100_bib9","first-page":"17","article-title":"Histoplasmosis mimicking adrenal carcinoma","volume":"78","author":"Pai","year":"2014","journal-title":"Conn Med"},{"key":"2024090310355353100_bib10","doi-asserted-by":"crossref","first-page":"2483","DOI":"10.1007\/s00330-005-2683-3","article-title":"High 18F-fluorodeoxyglocose uptake in adrenal histoplasmosis; 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