{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T07:28:56Z","timestamp":1781162936087,"version":"3.54.1"},"reference-count":23,"publisher":"Oxford University Press (OUP)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BJR|Open"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:sec><jats:title>Objectives:<\/jats:title><jats:p>To evaluate the effect of bowel dilation on cine-MRI small bowel motility measurements, by comparing a conventional motility score (including bowel wall and lumen) with a bowel wall-specific motility score in healthy and diseased populations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p>Four populations were included: 10 Crohn\u2019s patients with a stricture and prestricture dilation for segmental motility analysis, and 14 mannitol-prepared healthy subjects, 15 fasted healthy subjects and eight chronic intestinal pseudo-obstruction (CIPO) patients (characterized by dilated bowel loops) for global small bowel motility analysis. All subjects underwent a cine-MRI scan from which two motility scores were calculated: a conventional score (including bowel wall and lumen) and a bowel wall-specific score. The difference between the two scores was calculated per population and compared between groups with a one-way ANOVA and Tukey-Kramer analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>In Crohn\u2019s patients, the median (IQR) change between the conventional and wall-specific motility score was 0% (-2 to +4%) within the stricture and 0% (\u22121 to +7%) in the prestricture dilation. For the global small bowel, this was \u22121% (\u22125 to 0%) in mannitol-prepared healthy subjects, \u22122% (\u22126 to +2%) in fasted healthy subjects and +14% (+6\u2009to+20%) in CIPO patients. The difference between the two motility scores in CIPO patients differed significantly from the four other groups (p = 0.002\u2009to p &lt; 0.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions:<\/jats:title><jats:p>The conventional small bowel motility score seems robust in Crohn\u2019s disease patients and healthy subjects. In patients with globally and grossly dilated bowel loops, a bowel-wall specific motility score may give a better representation of small bowel motility.<\/jats:p><\/jats:sec><jats:sec><jats:title>Advances in knowledge:<\/jats:title><jats:p>These findings support researchers and clinicians with making informed choices for using cine-MRI motility analysis in different populations.<\/jats:p><\/jats:sec>","DOI":"10.1259\/bjro.20210049","type":"journal-article","created":{"date-parts":[[2022,2,10]],"date-time":"2022-02-10T17:38:45Z","timestamp":1644514725000},"source":"Crossref","is-referenced-by-count":2,"title":["Impact of bowel dilation on small bowel motility measurements with cine-MRI: assessment of two quantification techniques"],"prefix":"10.1093","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7937-5849","authenticated-orcid":false,"given":"Kyra L","family":"van Rijn","sequence":"first","affiliation":[{"name":"Department of Radiology and Nuclear Medicine, Amsterdam 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