{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T06:24:10Z","timestamp":1769840650252,"version":"3.49.0"},"reference-count":21,"publisher":"Oxford University Press (OUP)","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dentomaxillofacial Radiology"],"published-print":{"date-parts":[[2020,12,1]]},"abstract":"<jats:sec><jats:title>Objectives:<\/jats:title><jats:p> To investigate the assessment of inflammatory jaw pathologies using bone single-photon emission CT-CT (SPECT\/CT) maximum standardized uptake value (SUV<jats:sub>max<\/jats:sub>). <\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p> 44 patients with inflammatory jaw pathologies (7 chronic osteomyelitis, 8 osteoradionecrosis and 29 medication-related osteonecrosis of the jaw (MRONJ)) underwent SPECT\/CT at 4\u2009h after injection of <jats:sup>99m<\/jats:sup>Tc hydroxymethylene diphosphonate. The SPECT\/CT parameters SUV<jats:sub>max<\/jats:sub> of the inflammatory jaw pathologies were analyzed. Statistical analyses for the SUV<jats:sub>max<\/jats:sub> were performed by one-way repeated measures analysis of variance with Tukey's honestly significant difference test. A p-value lower than 0.05 was considered statistically significant. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p> The mean and standard deviation of SUV<jats:sub>max<\/jats:sub> for 7 chronic osteomyelitis, 8 osteoradionecrosis and 29 MRONJ were 24.94 \u00b1 3.65, 12.27 \u00b1 5.47\u2009and 16.55 \u00b1 9.12, respectively. The SUV<jats:sub>max<\/jats:sub> for chronic osteomyelitis were significantly higher than those for osteoradionecrosis (p = 0.011) and MRONJ (p = 0.043). <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions:<\/jats:title><jats:p> Bone SPECT\/CT SUV<jats:sub>max<\/jats:sub> in the uptake of <jats:sup>99m<\/jats:sup>Tc hydroxymethylene diphosphonate reflecting bone physiological changes for chronic osteomyelitis were significantly higher than those of osteonecrosis, such as osteoradionecrosis and MRONJ. Bone SPECT\/CT SUV<jats:sub>max <\/jats:sub>should be useful for the assessment of inflammatory jaw pathologies, such as chronic osteomyelitis, osteoradionecrosis and MRONJ. <\/jats:p><\/jats:sec>","DOI":"10.1259\/dmfr.20200043","type":"journal-article","created":{"date-parts":[[2020,6,3]],"date-time":"2020-06-03T17:14:27Z","timestamp":1591204467000},"page":"20200043","source":"Crossref","is-referenced-by-count":21,"title":["Assessment of inflammatory jaw pathologies using bone SPECT\/CT maximum standardized uptake value"],"prefix":"10.1093","volume":"49","author":[{"given":"Hiroo","family":"Toshima","sequence":"first","affiliation":[{"name":"Quantitative Diagnostic Imaging, Field of Oral and Maxillofacial Imaging and Histopathological Diagnostics, Course of Applied Science, The Nippon Dental University Graduate School of Life Dentistry at Niigata, Niigata, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9169-8429","authenticated-orcid":false,"given":"Ichiro","family":"Ogura","sequence":"additional","affiliation":[{"name":"Quantitative Diagnostic Imaging, Field of Oral and Maxillofacial Imaging and Histopathological Diagnostics, Course of Applied Science, The Nippon Dental University Graduate School of Life Dentistry at Niigata, Niigata, Japan"},{"name":"Department of Oral and Maxillofacial Radiology, The Nippon Dental University School of Life Dentistry at Niigata, Niigata, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","reference":[{"key":"b1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2016152294"},{"key":"b2","first-page":"262","volume":"6","author":"Kaneta T","year":"2016","journal-title":"Am J Nucl Med Mol Imaging"},{"key":"b3","doi-asserted-by":"publisher","DOI":"10.1186\/s13550-017-0300-5"},{"key":"b4","doi-asserted-by":"publisher","DOI":"10.1007\/s12149-017-1224-x"},{"key":"b5","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinimag.2018.06.009"},{"key":"b6","first-page":"169","volume":"20","author":"Sue M","year":"2017","journal-title":"Chin J Dent Res"},{"key":"b7","first-page":"219","volume":"20","author":"Ogura I","year":"2017","journal-title":"Chin J Dent Res"},{"key":"b8","doi-asserted-by":"publisher","DOI":"10.5430\/ijdi.v4n2p67"},{"key":"b9","doi-asserted-by":"publisher","DOI":"10.5114\/pjr.2018.80209"},{"key":"b10","doi-asserted-by":"publisher","DOI":"10.1007\/s11282-016-0268-2"},{"key":"b11","doi-asserted-by":"publisher","DOI":"10.12659\/PJR.902513"},{"key":"b12","doi-asserted-by":"publisher","DOI":"10.5624\/isd.2019.49.1.53"},{"key":"b13","doi-asserted-by":"publisher","DOI":"10.5624\/isd.2017.47.4.227"},{"key":"b14","first-page":"63","volume":"21","author":"Ogura I","year":"2018","journal-title":"Chin J Dent Res"},{"key":"b15","doi-asserted-by":"publisher","DOI":"10.1007\/s11282-019-00393-2"},{"key":"b16","doi-asserted-by":"publisher","DOI":"10.1016\/j.crad.2019.05.025"},{"key":"b17","doi-asserted-by":"publisher","DOI":"10.1007\/s12149-019-01390-5"},{"key":"b18","doi-asserted-by":"publisher","DOI":"10.5624\/isd.2019.49.4.281"},{"key":"b19","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2014.04.031"},{"key":"b20","doi-asserted-by":"publisher","DOI":"10.1186\/s40658-019-0241-3"},{"key":"b21","doi-asserted-by":"publisher","DOI":"10.1259\/dmfr.20190208"}],"container-title":["Dentomaxillofacial Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.birpublications.org\/doi\/pdf\/10.1259\/dmfr.20200043","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,12]],"date-time":"2024-01-12T15:55:14Z","timestamp":1705074914000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/dmfr\/article\/7262856"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12,1]]},"references-count":21,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2020,12,1]]}},"alternative-id":["10.1259\/dmfr.20200043"],"URL":"https:\/\/doi.org\/10.1259\/dmfr.20200043","relation":{},"ISSN":["0250-832X","1476-542X"],"issn-type":[{"value":"0250-832X","type":"print"},{"value":"1476-542X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,12,1]]}}}