{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T21:35:36Z","timestamp":1791495336021,"version":"4.3.4"},"reference-count":47,"publisher":"Oxford University Press (OUP)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dentomaxillofacial Radiology"],"published-print":{"date-parts":[[2021,5,1]]},"abstract":"<jats:sec><jats:title>Objectives:<\/jats:title><jats:p> The aim of this study was to investigate the relationship between pathological classification of parotid gland tumors and conventional MRI \u2013 diffusion-weighted imaging findings and also contribute the possible effect of apparent diffusion coefficient (ADC) to diagnosis. <\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p> 60 patients with parotid masses diagnosed using histopathology and\/or cytology were enrolled in this retrospective study. All patients were evaluated using a 1.5 T MRI. Demographic features, conventional MRI findings, and ADC values (mean, minimum, maximum, and relative) were recorded. MRI findings and ADC values were compared between benign\u2013malignant groups and pleomorphic adenoma vs Warthin\u2019s tumor groups. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p> 60 tumors (48 benign, 12 malignant) were evaluated in a total of 60 patients (39 males, 21 females). The mean age was 59 (\u00b114, 18\u201386) years old; the mean lesion size was 26 (\u00b110, 11\u201361)\u2009mm. On the texture of conventional MRI, T2 dominantly hyperintense\/with hypointensity signal was seen in 87% of pleomorphic adenomas and T2 dominantly hypointense\/with hyperintesity signal was encountered in 64% of all Warthin\u2019s tumors. Seven (28%) Warthin\u2019s tumors were misdiagnosed as pleomorphic adenomas and two others (8%) as malignant tumors. The commonly used mean ADC value was 1.6 \u00b1 0.6 \u00d7 10<jats:sup>\u20133<\/jats:sup>\u2009mm<jats:sup>2<\/jats:sup> s<jats:sup>\u22121<\/jats:sup> for benign tumors, 0.8 \u00b1 0.3 \u00d7 10<jats:sup>\u20133<\/jats:sup>\u2009mm<jats:sup>2<\/jats:sup> s<jats:sup>\u22121<\/jats:sup> for malign tumors, 1 (0.9\u20131.8) \u00d7 10<jats:sup>\u20133<\/jats:sup>\u2009mm<jats:sup>2<\/jats:sup> s<jats:sup>\u22121<\/jats:sup> for Warthin\u2019s tumors, and 1.9 \u00b1 0.3 \u00d7 10<jats:sup>\u20133<\/jats:sup>\u2009mm<jats:sup>2<\/jats:sup> s<jats:sup>\u22121<\/jats:sup> for pleomorphic adenomas. There was a statistically significant difference in ADC values between benign-malignant tumors and pleomorphic adenomas-Warthin\u2019s tumors. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions:<\/jats:title><jats:p> Warthin\u2019s tumor may occasionally be misdiagnosed as pleomorphic adenoma and malignant tumor because of variable morphologic features. In addition to benign\u2013malignant differentiation, the added ADC measurement may also be useful for differentiating Warthin\u2019s tumors from pleomorphic adenomas. <\/jats:p><\/jats:sec>","DOI":"10.1259\/dmfr.20200391","type":"journal-article","created":{"date-parts":[[2020,11,25]],"date-time":"2020-11-25T21:04:48Z","timestamp":1606338288000},"page":"20200391","source":"Crossref","is-referenced-by-count":36,"title":["Parotid gland tumors: comparison of conventional and diffusion-weighted MRI findings with histopathological results"],"prefix":"10.1093","volume":"50","author":[{"given":"Can Zafer","family":"Karaman","sequence":"first","affiliation":[{"name":"Department of Radiology, Ayd\u0131n Adnan Menderes University School of Medicine, Ayd\u0131n, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmet","family":"Tanyeri","sequence":"additional","affiliation":[{"name":"Department of Radiology, Ayd\u0131n Adnan Menderes University School of Medicine, Ayd\u0131n, Turkey"},{"name":"Department of Radiology, Yozgat City Hospital, Yozgat, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Recep","family":"\u00d6zg\u00fcr","sequence":"additional","affiliation":[{"name":"Department of Radiology, Ayd\u0131n Adnan Menderes University School of Medicine, Ayd\u0131n, Turkey"},{"name":"Department of Radiology, Devrek State Hospital, Zonguldak, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4388-3021","authenticated-orcid":false,"given":"Veli S\u00fcha","family":"\u00d6zt\u00fcrk","sequence":"additional","affiliation":[{"name":"Department of Radiology, Ayd\u0131n Adnan Menderes University School of Medicine, Ayd\u0131n, Turkey"},{"name":"Department of Radiology, Salihli State Hospital, Manisa, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","reference":[{"key":"b1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-84506-2"},{"key":"b2","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-5998(99)70323-2"},{"key":"b3","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2008.01.027"},{"key":"b4","doi-asserted-by":"publisher","DOI":"10.1159\/000331964"},{"key":"b5","doi-asserted-by":"publisher","DOI":"10.1159\/000075637"},{"key":"b6","doi-asserted-by":"publisher","DOI":"10.1159\/000326308"},{"key":"b7","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.185.3.1438746"},{"key":"b8","first-page":"116","volume":"28","author":"Eida S","year":"2007","journal-title":"AJNR Am J Neuroradiol"},{"key":"b9","doi-asserted-by":"publisher","DOI":"10.1055\/s-2005-858297"},{"key":"b10","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2213010131"},{"key":"b11","doi-asserted-by":"publisher","DOI":"10.1097\/00004728-200403000-00014"},{"key":"b12","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2019.03.897"},{"key":"b13","doi-asserted-by":"publisher","DOI":"10.1016\/j.nic.2018.01.009"},{"key":"b14","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A1412"},{"key":"b15","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0339(20000301)22:3<139::AID-DC2>3.0.CO;2-A"},{"key":"b16","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0339(199708)17:2<92::AID-DC3>3.0.CO;2-Q"},{"key":"b17","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2014.09.025"},{"key":"b18","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjoms.2015.03.015"},{"key":"b19","doi-asserted-by":"publisher","DOI":"10.1259\/dmfr\/15047967"},{"key":"b20","first-page":"83","volume":"9","author":"Fassnacht W","year":"2013","journal-title":"B-ENT"},{"key":"b21","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2003.07.009"},{"key":"b22","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A2520"},{"key":"b23","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.173.3.2813793"},{"key":"b24","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.163.2.3562818"},{"key":"b25","doi-asserted-by":"publisher","DOI":"10.1148\/rg.266065014"},{"key":"b26","doi-asserted-by":"publisher","DOI":"10.1148\/rg.291085072"},{"key":"b28","doi-asserted-by":"publisher","DOI":"10.1259\/bjr.20150912"},{"key":"b29","doi-asserted-by":"publisher","DOI":"10.4317\/medoral.20337"},{"key":"b30","volume-title":"Tumors of the head and neck: clinical and pathological considerations","author":"Batsakis JG","year":"1979","edition":"2"},{"key":"b31","first-page":"555","volume":"17","author":"Ikeda K","year":"1996","journal-title":"AJNR Am J Neuroradiol"},{"key":"b32","doi-asserted-by":"publisher","DOI":"10.1016\/S0009-9260(05)81748-9"},{"key":"b33","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinimag.2017.06.009"},{"key":"b34","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.09090021"},{"key":"b35","doi-asserted-by":"publisher","DOI":"10.1016\/S0720-048X(02)00303-0"},{"key":"b36","doi-asserted-by":"publisher","DOI":"10.1002\/1522-2594(200006)43:6<828::AID-MRM8>3.0.CO;2-P"},{"key":"b37","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2202010063"},{"key":"b38","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurad.2007.04.002"},{"key":"b39","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinimag.2012.04.025"},{"key":"b40","doi-asserted-by":"publisher","DOI":"10.1007\/s11547-018-0940-1"},{"key":"b41","doi-asserted-by":"publisher","DOI":"10.1002\/nbm.2962"},{"key":"b42","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2493072045"},{"key":"b43","doi-asserted-by":"publisher","DOI":"10.1259\/dmfr.20170343"},{"key":"b44","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.11.7093"},{"key":"b45","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2005.02.004"},{"key":"b46","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.06.1403"},{"key":"b47","doi-asserted-by":"publisher","DOI":"10.1016\/j.crad.2014.01.011"},{"key":"b48","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2492071681"}],"container-title":["Dentomaxillofacial Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.birpublications.org\/doi\/pdf\/10.1259\/dmfr.20200391","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,12]],"date-time":"2024-01-12T15:55:28Z","timestamp":1705074928000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/dmfr\/article\/7242211"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5,1]]},"references-count":47,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,5,1]]}},"alternative-id":["10.1259\/dmfr.20200391"],"URL":"https:\/\/doi.org\/10.1259\/dmfr.20200391","relation":{},"ISSN":["0250-832X","1476-542X"],"issn-type":[{"value":"0250-832X","type":"print"},{"value":"1476-542X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,5,1]]}}}