{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T08:44:30Z","timestamp":1778575470052,"version":"3.51.4"},"reference-count":42,"publisher":"Oxford University Press (OUP)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dentomaxillofacial Radiology"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:sec><jats:title>Objectives:<\/jats:title><jats:p> Limited studies have differentiated radicular cysts and granulomas with MRI. Therefore, we investigated the MRI characteristics of the two lesions and clarified features for distinguishing between them. <\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p> We collected data of 27 radicular cysts and 9 granulomas definitively diagnosed by histopathology and reviewed the fat-saturated T<jats:sub>2<\/jats:sub> weighted, T<jats:sub>1<\/jats:sub> weighted, and contrast-enhanced fat-saturated T<jats:sub>1<\/jats:sub> weighted images. We measured the maximum diameter and apparent diffusion coefficient values of the lesions. We employed Fisher\u2019s exact test, the Mann\u2013Whitney U test, and independent t-tests to compare the two lesions and created a decision tree for discriminating between them. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p> There were significant differences between radicular cysts and granulomas with respect to five imaging characteristics\u2014signal intensity of the lesion centre on fat-saturated T<jats:sub>2<\/jats:sub> weighted images; signal intensity, texture, and contrast enhancement of the lesion centre on contrast-enhanced fat-saturated T<jats:sub>1<\/jats:sub> weighted images; and maximum diameter of the lesion. The cut-off diameter for radicular cysts was 15.9\u2009mm. The area under the receiver operating characteristic curve, sensitivity, and specificity were 0.971, 85.2%, and 100%, respectively. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions:<\/jats:title><jats:p> From the decision tree analysis, maximum diameter, lesion centre contrast enhancement on contrast-enhanced fat-saturated T<jats:sub>1<\/jats:sub> weighted images, and lesion centre signal intensity on fat-saturated T<jats:sub>2<\/jats:sub> weighted images were important for discriminating between radicular cysts and granulomas. <\/jats:p><\/jats:sec>","DOI":"10.1259\/dmfr.20220336","type":"journal-article","created":{"date-parts":[[2023,1,23]],"date-time":"2023-01-23T14:05:36Z","timestamp":1674482736000},"source":"Crossref","is-referenced-by-count":7,"title":["The magnetic resonance imaging characteristics of radicular cysts and granulomas"],"prefix":"10.1093","volume":"52","author":[{"given":"Natnicha","family":"Wamasing","sequence":"first","affiliation":[{"name":"Dental Radiology and Radiation Oncology, Graduate School of Dentistry, Tokyo Medical and Dental University, Yushima 1-5-45, Bunkyo-ku, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Supasith","family":"Yomtako","sequence":"additional","affiliation":[{"name":"Dental Radiology and Radiation Oncology, Graduate School of Dentistry, Tokyo Medical and Dental University, Yushima 1-5-45, Bunkyo-ku, Tokyo, Japan"},{"name":"School of Dentistry, Mae Fah Luang University, 333 Moo1, Tshasud, Muang, Chiangrai, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Watanabe","sequence":"additional","affiliation":[{"name":"Dental Radiology and Radiation Oncology, Graduate School of Dentistry, Tokyo Medical and Dental University, Yushima 1-5-45, Bunkyo-ku, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junichiro","family":"Sakamoto","sequence":"additional","affiliation":[{"name":"Dental Radiology and Radiation Oncology, Graduate School of Dentistry, Tokyo Medical and Dental University, Yushima 1-5-45, Bunkyo-ku, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kou","family":"Kayamori","sequence":"additional","affiliation":[{"name":"Oral Pathology, Graduate School of Dentistry, Tokyo Medical and Dental University, Yushima 1-5-45, Bunkyo-ku, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tohru","family":"Kurabayashi","sequence":"additional","affiliation":[{"name":"Dental Radiology and Radiation Oncology, Graduate School of Dentistry, Tokyo Medical and Dental University, Yushima 1-5-45, Bunkyo-ku, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","reference":[{"key":"b1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2041-1626.2011.00053.x"},{"key":"b3","author":"Nair PN","year":"2000","journal-title":"Periodontol"},{"key":"b4","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2013.08.019"},{"key":"b5","doi-asserted-by":"publisher","DOI":"10.1016\/S1079-2104(96)80156-9"},{"key":"b6","doi-asserted-by":"publisher","DOI":"10.1016\/S0099-2399(80)80039-2"},{"key":"b7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2591.2008.01484.x"},{"key":"b8","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2591.1998.00146.x"},{"key":"b9","volume-title":"Hargreaves KM,Rotstein I. 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