{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T05:38:13Z","timestamp":1777354693435,"version":"3.51.4"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dentomaxillofacial Radiology"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:sec><jats:title>Objectives:<\/jats:title><jats:p> Warthin\u2019s tumors (WT) and pleomorphic adenomas (PA) are the commonest parotid gland tumors; however, their differentiation remains difficult. This study aimed to investigate the utility of the apparent diffusion coefficient (ADC) value, texture features, and their combination for the differential diagnosis of parotid gland tumors. <\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p> Patients who underwent magnetic resonance imaging (MRI) between April 2008 and March 2021 for parotid gland tumors were included and divided into two groups according to the tumor type: WT and PA. The tumor types were used as predictor variables, while the ADC value, texture features, and their combination were the outcome variables. Texture features were measured on short tau inversion recovery (STIR) images and selected using the Fisher\u2019s coefficient method and probability of error, and average correlation coefficients. The Mann-Whitney U-test was used to analyze bivariate statistics. Receiver operating characteristic curve analysis was used to assess the ability of the ADC value, texture features, and their combination to distinguishing between the two tumor types. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p> A total of 22 patients were included, 11 in each group. The ADC value, 10 texture features, and their combination were significantly different between the two groups (p &lt; .001). Moreover, all three variables had high area under the curve values of 0.93\u20130.96. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion:<\/jats:title><jats:p> The ADC value, texture features, and their combination demonstrated good diagnostic ability to distinguish between WTs and PAs. This method may be used to aid the differential diagnosis of parotid gland tumors, thereby promoting timely and adequate treatment. <\/jats:p><\/jats:sec>","DOI":"10.1259\/dmfr.20220404","type":"journal-article","created":{"date-parts":[[2023,4,4]],"date-time":"2023-04-04T22:56:55Z","timestamp":1680649015000},"source":"Crossref","is-referenced-by-count":7,"title":["Differential diagnosis of parotid gland tumors using apparent diffusion coefficient, texture features, and their combination"],"prefix":"10.1093","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5764-2002","authenticated-orcid":false,"given":"Hirotaka","family":"Muraoka","sequence":"first","affiliation":[{"name":"Department of Radiology, Nihon University School of Dentistry at Matsudo 2-870-1 Sakaecho-Nishi, Matsudo, Chiba, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Kaneda","sequence":"additional","affiliation":[{"name":"Department of Radiology, Nihon University School of Dentistry at Matsudo 2-870-1 Sakaecho-Nishi, Matsudo, Chiba, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takumi","family":"Kondo","sequence":"additional","affiliation":[{"name":"Department of Radiology, Nihon University School of Dentistry at Matsudo 2-870-1 Sakaecho-Nishi, Matsudo, Chiba, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shunya","family":"Okada","sequence":"additional","affiliation":[{"name":"Department of Radiology, Nihon University School of Dentistry at Matsudo 2-870-1 Sakaecho-Nishi, Matsudo, Chiba, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"Tokunaga","sequence":"additional","affiliation":[{"name":"Department of Radiology, Nihon University School of Dentistry at Matsudo 2-870-1 Sakaecho-Nishi, Matsudo, Chiba, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","reference":[{"key":"b1","doi-asserted-by":"publisher","DOI":"10.1007\/s12105-017-0795-0"},{"key":"b2","first-page":"2097","volume-title":"Head and Neck Imaging","author":"Som PM","year":"2003","edition":"4"},{"key":"b3","doi-asserted-by":"publisher","DOI":"10.1007\/s12105-011-0281-z"},{"key":"b4","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A1412"},{"key":"b5","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2493072045"},{"key":"b6","doi-asserted-by":"publisher","DOI":"10.12659\/MSM.911185"},{"key":"b7","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-019-04447-9"},{"key":"b8","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-018-5052-y"},{"key":"b9","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2262011486"},{"key":"b10","doi-asserted-by":"publisher","DOI":"10.1259\/dmfr.20210321"},{"key":"b11","doi-asserted-by":"publisher","DOI":"10.1186\/s40644-019-0193-9"},{"key":"b12","doi-asserted-by":"publisher","DOI":"10.1007\/s11282-022-00595-1"},{"key":"b13","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2019.108654"},{"key":"b14","doi-asserted-by":"publisher","DOI":"10.1016\/j.crad.2020.06.018"},{"key":"b15","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2013.281053"},{"key":"b16","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmpb.2008.08.005"},{"key":"b17","unstructured":"MaZda - a software for texture analysis. 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