{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T21:59:21Z","timestamp":1775599161330,"version":"3.50.1"},"reference-count":17,"publisher":"Oxford University Press (OUP)","issue":"1130","license":[{"start":{"date-parts":[[2021,12,20]],"date-time":"2021-12-20T00:00:00Z","timestamp":1639958400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,2,1]]},"abstract":"<jats:p>Brenner tumors are rare ovarian neoplasms composed of ovarian transition cells surrounded by dense fibrous tissue. Most of them are small tumors (&amp;lt;2 cm), detected incidentally in asymptomatic women. Its predominantly fibrous content results in relatively low signal on T \u00a02 weighted images, establishing differential diagnosis with ovarian fibroma and thecoma. Their imaging features are very similar, the differentiation is based on secondary characteristics, such as signs or symptoms of estrogen excess and the presence of a second ovarian neoplasm, which has been reported in up to 30% of patients with Brenner tumor. Although originally thought to be universally benign, there have been scattered reports in the past decades of borderline and malignant forms of Brenner tumors.<\/jats:p>","DOI":"10.1259\/bjr.20210687","type":"journal-article","created":{"date-parts":[[2021,12,20]],"date-time":"2021-12-20T16:48:42Z","timestamp":1640018922000},"source":"Crossref","is-referenced-by-count":15,"title":["Brenner tumors"],"prefix":"10.1093","volume":"95","author":[{"given":"Filipa de Sousa","family":"Costeira","sequence":"first","affiliation":[{"name":"Hospital de Braga , Braga , Portugal"}]},{"given":"Ana","family":"F\u00e9lix","sequence":"additional","affiliation":[{"name":"Instituto Portugues de Oncologia de Lisboa Francisco Gentil , Lisbon , Portugal"}]},{"given":"Teresa Margarida","family":"Cunha","sequence":"additional","affiliation":[{"name":"Instituto Portugues de Oncologia de Lisboa Francisco Gentil , Lisbon , Portugal"}]}],"member":"286","published-online":{"date-parts":[[2021,12,20]]},"reference":[{"key":"2024050216110421900_b1","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1148\/rg.226025033","article-title":"Ct and MR imaging of ovarian tumors with emphasis on differential diagnosis","volume":"22","author":"Jung","year":"2002","journal-title":"Radiographics"},{"key":"2024050216110421900_b2","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1002\/1097-0142(197103)27:3<687::AID-CNCR2820270326>3.0.CO;2-C","article-title":"Proliferating Brenner tumors","volume":"27","author":"Roth","year":"1971","journal-title":"Cancer"},{"key":"2024050216110421900_b3","volume-title":"Female genital tumours. in: WHO classification of tumours","author":"WHO Classification of Tumours Editorial Board","year":"2020"},{"key":"2024050216110421900_b4","volume-title":"Pathology and genetics of tumours of the breast and female genital organs","author":"Eble","year":"2003"},{"key":"2024050216110421900_b5","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1002\/1097-0142(197207)30:1<174::AID-CNCR2820300125>3.0.CO;2-D","article-title":"Proliferative and malignant Brenner tumors of the ovary","volume":"30","author":"Miles","year":"1972","journal-title":"Cancer"},{"key":"2024050216110421900_b6","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.5858\/arpa.2018-0285-RS","article-title":"Borderline Brenner tumor: a review of the literature","volume":"143","author":"Zheng","year":"2019","journal-title":"Arch Pathol Lab Med"},{"key":"2024050216110421900_b7","first-page":"269","volume-title":"MRI of the female pelvis. 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