{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T20:43:25Z","timestamp":1782506605835,"version":"3.54.5"},"reference-count":21,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2005,7,1]],"date-time":"2005-07-01T00:00:00Z","timestamp":1120176000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Bioscience and Bioengineering"],"published-print":{"date-parts":[[2005,7]]},"DOI":"10.1263\/jbb.100.77","type":"journal-article","created":{"date-parts":[[2005,8,9]],"date-time":"2005-08-09T05:54:55Z","timestamp":1123566895000},"page":"77-81","source":"Crossref","is-referenced-by-count":23,"title":["Availability of bone marrow stromal cells in three-dimensional coculture with hepatocytes and transplantation into liver-damaged mice"],"prefix":"10.1016","volume":"100","author":[{"given":"Masashi","family":"Takeda","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marii","family":"Yamamoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katsuhiro","family":"Isoda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinji","family":"Higashiyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Motohiro","family":"Hirose","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hajime","family":"Ohgushi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaya","family":"Kawase","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiyohito","family":"Yagi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1263\/jbb.100.77_bib1","doi-asserted-by":"crossref","first-page":"1422","DOI":"10.1056\/NEJM199805143382004","article-title":"Treatment of the Crigler-Najjar syndrome type I with hepatocyte transplantation","volume":"338","author":"Fox","year":"1998","journal-title":"N. Engl. J. Med."},{"key":"10.1263\/jbb.100.77_bib2","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1055\/s-2007-1007096","article-title":"Hepatocyte transplantation for the treatment of human disease","volume":"19","author":"Strom","year":"1999","journal-title":"Semin. Liver Dis."},{"key":"10.1263\/jbb.100.77_bib3","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1097\/00007890-200001270-00018","article-title":"Defining hepatocellular chimerism in a liver failure patient bridged with hepatocyte infusion","volume":"69","author":"Fisher","year":"2000","journal-title":"Transplantation"},{"key":"10.1263\/jbb.100.77_bib4","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1097\/00007890-199608150-00010","article-title":"Correction of an inborn error of metabolism by intraportal hepatocyte transplantation in a dog model","volume":"62","author":"Kocken","year":"1996","journal-title":"Transplantation"},{"key":"10.1263\/jbb.100.77_bib5","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1159\/000008619","article-title":"Prolonged function of hepatocytes transplanted into the spleens of Nagase analbuminemic rats","volume":"31","author":"Ikebukuro","year":"1999","journal-title":"Eur. Surg. Res."},{"key":"10.1263\/jbb.100.77_bib6","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1053\/he.2000.5636","article-title":"Hepatocyte transplantation in rats with decompensated cirrhosis","volume":"31","author":"Kobayashi","year":"2000","journal-title":"Hepatology"},{"key":"10.1263\/jbb.100.77_bib7","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1097\/00007890-197912000-00013","article-title":"Morphology and function of isolated hepatocytes transplanted into rat spleen","volume":"28","author":"Mito","year":"1979","journal-title":"Transplantation"},{"key":"10.1263\/jbb.100.77_bib8","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S1389-1723(03)90102-2","article-title":"Transplantation of hepatocytes cultured on hydorxyapatite into Nagase analbuminemia rats","volume":"96","author":"Higashiyama","year":"2003","journal-title":"J. Biosci. Bioeng."},{"key":"10.1263\/jbb.100.77_bib9","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1016\/0922-338X(96)87734-8","article-title":"In vitro maintenance of liver function in hierarchical co-culture of hepatocytes and non-parenchymal liver cells","volume":"80","author":"Yagi","year":"1995","journal-title":"J. Ferment. Bioeng."},{"key":"10.1263\/jbb.100.77_bib10","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.bej.2003.07.002","article-title":"Maintenance of hepatocyte functions in co-culture of hepatic stellate cells","volume":"20","author":"Higashiyama","year":"2004","journal-title":"Biochem. Eng. J."},{"key":"10.1263\/jbb.100.77_bib11","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1038\/ni916","article-title":"A stromal cell-derived membrane protein that supports hematopoietic stem cells","volume":"4","author":"Ueno","year":"2003","journal-title":"Nat. Immunol."},{"key":"10.1263\/jbb.100.77_bib12","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1089\/152581601750098372","article-title":"Immortalized multipotential mesenchymal cells and the hematopoietic microenvironment","volume":"10","author":"Dormady","year":"2001","journal-title":"J. Hematother. Stem Cell Res."},{"key":"10.1263\/jbb.100.77_bib13","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/S1389-1723(04)70217-0","article-title":"Maintenance of hepatocyte functions by co-culture with bone marrow stromal cells","volume":"97","author":"Isoda","year":"2004","journal-title":"J. Biosci. Bioeng."},{"key":"10.1263\/jbb.100.77_bib14","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/S0091-679X(08)61797-5","article-title":"Preparation of isolated rat liver cells","volume":"13","author":"Seglen","year":"1976","journal-title":"Methods Cell Biol."},{"key":"10.1263\/jbb.100.77_bib15","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1007\/BF02983527","article-title":"Stem cell plasticity in the hematopoietic system","volume":"79","author":"Heike","year":"2004","journal-title":"Int. J. Hematol."},{"key":"10.1263\/jbb.100.77_bib16","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1038\/sj.thj.6200232","article-title":"Mesenchymal stem cell: use and perspectives","volume":"4","author":"Tocci","year":"2003","journal-title":"Hematol. J."},{"key":"10.1263\/jbb.100.77_bib17","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1002\/jbm.820271107","article-title":"Osteogenic differentiation of marrow stromal stem cells in porous hydroxyapatite ceramics","volume":"27","author":"Ohgushi","year":"1993","journal-title":"J. Biomed. Mater. Res."},{"key":"10.1263\/jbb.100.77_bib18","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1126\/science.451621","article-title":"Albumin-deficient rat mutant","volume":"205","author":"Nagase","year":"1979","journal-title":"Science"},{"key":"10.1263\/jbb.100.77_bib19","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/S0167-4889(02)00326-9","article-title":"The role of cytokines in liver failure and regeneration: potential new molecular therapies","volume":"1592","author":"Galun","year":"2002","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1263\/jbb.100.77_bib20","doi-asserted-by":"crossref","first-page":"26605","DOI":"10.1074\/jbc.M100740200","article-title":"Interleukin-6 protects against Fas-mediated death by establishing a critical level of anti-apoptotic hepatic proteins FLIP, Bcl-2, and Bcl-xL","volume":"276","author":"Kovalovich","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1263\/jbb.100.77_bib21","doi-asserted-by":"crossref","first-page":"1560","DOI":"10.1182\/blood.V89.5.1560","article-title":"Hepatocyte growth factor is constitutively produced by human bone marrow stromal cells and indirectly promotes hematopoiesis","volume":"89","author":"Takai","year":"1997","journal-title":"Blood"}],"container-title":["Journal of Bioscience and Bioengineering"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S138917230570431X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S138917230570431X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,4,8]],"date-time":"2020-04-08T19:31:48Z","timestamp":1586374308000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S138917230570431X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,7]]},"references-count":21,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2005,7]]}},"alternative-id":["S138917230570431X"],"URL":"https:\/\/doi.org\/10.1263\/jbb.100.77","relation":{},"ISSN":["1389-1723"],"issn-type":[{"value":"1389-1723","type":"print"}],"subject":[],"published":{"date-parts":[[2005,7]]}}}