{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,8]],"date-time":"2026-08-08T05:43:37Z","timestamp":1786167817224,"version":"build-2736575974"},"reference-count":44,"publisher":"Japanese Society for Hygiene","issue":"0","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Environ. Health Prev. Med.","Environ Health Prev Med"],"published-print":{"date-parts":[[2026]]},"DOI":"10.1265\/ehpm.25-00400","type":"journal-article","created":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T22:10:41Z","timestamp":1786054241000},"page":"52-52","source":"Crossref","is-referenced-by-count":0,"title":["Reproductive factors and brain volume in community-dwelling individuals: the Ohasama Study"],"prefix":"10.1265","volume":"31","author":[{"given":"Ayana","family":"Saito","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Akita University Graduate School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1453-4540","authenticated-orcid":false,"given":"Kyoko","family":"Nomura","sequence":"additional","affiliation":[{"name":"Department of Environmental Health Science and Public Health, Akita University Graduate School of Medicine"},{"name":"Department of Hygiene and Public Health, Teikyo University School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michihiro","family":"Satoh","sequence":"additional","affiliation":[{"name":"Division of Public Health, Hygiene and Epidemiology, Faculty of Medicine, Tohoku Medical and Pharmaceutical University"},{"name":"Department of Preventive Medicine and Epidemiology, Tohoku Medical Megabank Organization, Tohoku University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoshi","family":"Yamaguchi","sequence":"additional","affiliation":[{"name":"Division of Aging and Geriatric Dentistry, Department of Rehabilitation Dentistry, Tohoku University Graduate School of Dentistry"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Azusa","family":"Hara","sequence":"additional","affiliation":[{"name":"Laboratory of Social Pharmacy and Epidemiology, Showa Pharmaceutical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melanie","family":"Griffith-Quintyne","sequence":"additional","affiliation":[{"name":"Department of Environmental Health Science and Public Health, Akita University Graduate School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroaki","family":"Shimizu","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Akita University Graduate School of Medicine"},{"name":"Akita Prefectural Hospital Organization"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shingo","family":"Nakayama","sequence":"additional","affiliation":[{"name":"Division of Public Health, Hygiene and Epidemiology, Faculty of Medicine, Tohoku Medical and Pharmaceutical University"},{"name":"Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megumi","family":"Tsubota-Utsugi","sequence":"additional","affiliation":[{"name":"Department of Hygiene and Public Health, Teikyo University School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takahisa","family":"Murakami","sequence":"additional","affiliation":[{"name":"Division of Public Health, Hygiene and Epidemiology, Faculty of Medicine, Tohoku Medical and Pharmaceutical University"},{"name":"Department of Preventive Medicine and Epidemiology, Tohoku Medical Megabank Organization, Tohoku University"},{"name":"Division of Aging and Geriatric Dentistry, Department of Rehabilitation Dentistry, Tohoku University Graduate School of Dentistry"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yukako","family":"Tatsumi","sequence":"additional","affiliation":[{"name":"Department of Hygiene and Public Health, Teikyo University School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takuo","family":"Hirose","sequence":"additional","affiliation":[{"name":"Division of Nephrology and Hypertension, Faculty of Medicine, Tohoku Medical and Pharmaceutical University"},{"name":"Division of Integrative Renal Replacement Therapy, Faculty of Medicine, Tohoku Medical and Pharmaceutical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoko","family":"Totsune","sequence":"additional","affiliation":[{"name":"Department of Aging Research and Geriatric Medicine, Institute of Development, Aging and Cancer, Tohoku University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoko","family":"Mori","sequence":"additional","affiliation":[{"name":"Department of Radiology, Akita University Graduate School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kei","family":"Asayama","sequence":"additional","affiliation":[{"name":"Department of Hygiene and Public Health, Teikyo University School of Medicine"},{"name":"Tohoku Institute for Management of Blood Pressure"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiro","family":"Kikuya","sequence":"additional","affiliation":[{"name":"Department of Hygiene and Public Health, Teikyo University School of Medicine"},{"name":"Department of Preventive Medicine and Epidemiology, Tohoku Medical Megabank Organization, Tohoku University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirohito","family":"Metoki","sequence":"additional","affiliation":[{"name":"Division of Public Health, Hygiene and Epidemiology, Faculty of Medicine, Tohoku Medical and Pharmaceutical University"},{"name":"Department of Preventive Medicine and Epidemiology, Tohoku Medical Megabank Organization, Tohoku University"},{"name":"Tohoku Institute for Management of Blood Pressure"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsushi","family":"Hozawa","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine and Epidemiology, Tohoku Medical Megabank Organization, Tohoku University"},{"name":"Division of Epidemiology, School of Public Health, Tohoku University Graduate School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takayoshi","family":"Ohkubo","sequence":"additional","affiliation":[{"name":"Department of Hygiene and Public Health, Teikyo University School of Medicine"},{"name":"Department of Preventive Medicine and Epidemiology, Tohoku Medical Megabank Organization, Tohoku University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"335","reference":[{"key":"1","doi-asserted-by":"publisher","unstructured":"1. de Kleijn MJ, van der Schouw YT, van der Graaf Y. Reproductive history and cardiovascular disease risk in postmenopausal women: a review of the literature. Maturitas. 1999;33:7\u201336. https:\/\/doi.org\/10.1016\/s0378-5122(99)00038-9.","DOI":"10.1016\/S0378-5122(99)00038-9"},{"key":"2","doi-asserted-by":"publisher","unstructured":"2. Charalampopoulos D, McLoughlin A, Elks CE, Ong KK. Age at menarche and risks of all-cause and cardiovascular death: a systematic review and meta-analysis. Am J Epidemiol. 2014;180:29\u201340. https:\/\/doi.org\/10.1093\/aje\/kwu113.","DOI":"10.1093\/aje\/kwu113"},{"key":"3","doi-asserted-by":"publisher","unstructured":"3. Sato W, Nomura K, Satoh M, Hara A, Tsubota-Utsugi M, Murakami T, et al. Female Reproductive Events and Subclinical Atherosclerosis of the Brain and Carotid Arteriopathy: the Ohasama Study. J Atheroscler Thromb. 2023;30:956\u201378. https:\/\/doi.org\/10.5551\/jat.63592.","DOI":"10.5551\/jat.63592"},{"key":"4","doi-asserted-by":"publisher","unstructured":"4. Yamazaki T, Nomura K, Satoh M, Hara A, Tsubota-Utsugi M, Murakami T, et al. Association Between the Number of Deliveries and Cognitive Impairment Considering the Presence of Subclinical Cerebrovascular Diseases: The Ohasama Study. Tohoku J Exp Med. 2025;266:69\u201379. https:\/\/doi.org\/10.1620\/tjem.2024.J139.","DOI":"10.1620\/tjem.2024.J139"},{"key":"5","doi-asserted-by":"publisher","unstructured":"5. Szoeke C, Downie SJ, Parker AF, Phillips S. Sex hormones, vascular factors and cognition. Front Neuroendocrinol. 2021;62:100927. https:\/\/doi.org\/10.1016\/j.yfrne.2021.100927.","DOI":"10.1016\/j.yfrne.2021.100927"},{"key":"6","doi-asserted-by":"publisher","unstructured":"6. Vargas KG, Milic J, Zaciragic A, Wen KX, Jaspers L, Nano J, et al. The functions of estrogen receptor beta in the female brain: A systematic review. Maturitas. 2016;93:41\u201357. https:\/\/doi.org\/10.1016\/j.maturitas.2016.05.014.","DOI":"10.1016\/j.maturitas.2016.05.014"},{"key":"7","doi-asserted-by":"publisher","unstructured":"7. Singh M, Krishnamoorthy VR, Kim S, Khurana S, LaPorte HM. Brain-derived neuerotrophic factor and related mechanisms that mediate and influence progesterone-induced neuroprotection. Front Endocrinol (Lausanne). 2024;15:1286066. https:\/\/doi.org\/10.3389\/fendo.2024.1286066.","DOI":"10.3389\/fendo.2024.1286066"},{"key":"8","doi-asserted-by":"publisher","unstructured":"8. Ulhaq ZS, Garcia CP. Estrogen receptor beta (ESR2) gene polymorphism and susceptibility to dementia. Acta Neurol Belg. 2021;121:1281\u201393. https:\/\/doi.org\/10.1007\/s13760-020-01360-z.","DOI":"10.1007\/s13760-020-01360-z"},{"key":"9","doi-asserted-by":"publisher","unstructured":"9. Blinkouskaya Y, Ca\u00e7oilo A, Gollamudi T, Jalalian S, Weickenmeier J. Brain aging mechanisms with mechanical manifestations. Mech Ageing Dev. 2021;200:111575. https:\/\/doi.org\/10.1016\/j.mad.2021.111575.","DOI":"10.1016\/j.mad.2021.111575"},{"key":"10","doi-asserted-by":"publisher","unstructured":"10. Pettemeridou E, Kallousia E, Constantinidou F. Regional Brain Volume, Brain Reserve and MMSE Performance in Healthy Aging From the NEUROAGE Cohort: Contributions of Sex, Education, and Depression Symptoms. Front Aging Neurosci. 2021;13. https:\/\/doi.org\/10.3389\/fnagi.2021.711301.","DOI":"10.3389\/fnagi.2021.711301"},{"key":"11","doi-asserted-by":"publisher","unstructured":"11. Schelbaum E, Loughlin L, Jett S, Zhang C, Jang G, Malviya N, et al. Association of Reproductive History With Brain MRI Biomarkers of Dementia Risk in Midlife. Neurology. 2021;97:e2328\u201339. https:\/\/doi.org\/10.1212\/wnl.0000000000012941.","DOI":"10.1212\/WNL.0000000000012941"},{"key":"12","doi-asserted-by":"publisher","unstructured":"12. Ambikairajah A, Tabatabaei-Jafari H, Hornberger M, Cherbuin N. Age, menstruation history, and the brain. Menopause. 2020;28:167\u201374. https:\/\/doi.org\/10.1097\/gme.0000000000001688.","DOI":"10.1097\/GME.0000000000001688"},{"key":"13","doi-asserted-by":"publisher","unstructured":"13. Moir ME, Corkery AT, Senese KA, Miller KB, Pearson AG, Loggie NA, et al. Age at natural menopause impacts cerebrovascular reactivity and brain structure. Am J Physiol Regul Integr Comp Physiol. 2023;324:R207\u201315. https:\/\/doi.org\/10.1152\/ajpregu.00228.2022.","DOI":"10.1152\/ajpregu.00228.2022"},{"key":"14","doi-asserted-by":"publisher","unstructured":"14. Aleknaviciute J, Evans TE, Aribas E, de Vries MW, Steegers EAP, Ikram MA, et al. Long-term association of pregnancy and maternal brain structure: the Rotterdam Study. Eur J Epidemiol. 2022;37:271\u201381. https:\/\/doi.org\/10.1007\/s10654-021-00818-5.","DOI":"10.1007\/s10654-021-00818-5"},{"key":"15","doi-asserted-by":"publisher","unstructured":"15. Jung JH, Lee GW, Lee JH, Byun MS, Yi D, Jeon SY, et al. Multiparity, Brain Atrophy, and Cognitive Decline. Front Aging Neurosci. 2020;12:159. https:\/\/doi.org\/10.3389\/fnagi.2020.00159.","DOI":"10.3389\/fnagi.2020.00159"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Imai Y, Nagai K, Sakuma M, Sakuma H, Nakatsuka H, Satoh H, et al. Ambulatory blood pressure of adults in Ohasama, Japan. Hypertension. 1993;22:900\u201312. https:\/\/doi.org\/10.1161\/01.hyp.22.6.900.","DOI":"10.1161\/01.HYP.22.6.900"},{"key":"17","doi-asserted-by":"publisher","unstructured":"17. Murakami K, Tsubota-Utsugi M, Satoh M, Asayama K, Inoue R, Ishiguro A, et al. Impaired Higher-Level Functional Capacity as a Predictor of Stroke in Community-Dwelling Older Adults: The Ohasama Study. Stroke. 2016;47:323\u20138. https:\/\/doi.org\/10.1161\/strokeaha.115.011131.","DOI":"10.1161\/STROKEAHA.115.011131"},{"key":"18","doi-asserted-by":"publisher","unstructured":"18. Maldjian JA, Laurienti PJ, Kraft RA, Burdette JH. An automated method for neuroanatomic and cytoarchitectonic atlas-based interrogation of fMRI data sets. Neuroimage. 2003;19:1233\u20139. https:\/\/doi.org\/10.1016\/s1053-8119(03)00169-1.","DOI":"10.1016\/S1053-8119(03)00169-1"},{"key":"19","doi-asserted-by":"publisher","unstructured":"19. Maldjian JA, Laurienti PJ, Burdette JH. Precentral gyrus discrepancy in electronic versions of the Talairach atlas. Neuroimage. 2004;21:450\u20135. https:\/\/doi.org\/10.1016\/j.neuroimage.2003.09.032.","DOI":"10.1016\/j.neuroimage.2003.09.032"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Lancaster JL, Woldorff MG, Parsons LM, Liotti M, Freitas CS, Rainey L, et al. Automated Talairach atlas labels for functional brain mapping. Hum Brain Mapp. 2000;10:120\u201331. https:\/\/doi.org\/10.1002\/1097-0193(200007)10:3&lt;120::aid-hbm30&gt;3.0.co;2-8.","DOI":"10.1002\/1097-0193(200007)10:3<120::AID-HBM30>3.0.CO;2-8"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Tzourio-Mazoyer N, Landeau B, Papathanassiou D, Crivello F, Etard O, Delcroix N, et al. Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single-subject brain. Neuroimage. 2002;15:273\u201389. https:\/\/doi.org\/10.1006\/nimg.2001.0978.","DOI":"10.1006\/nimg.2001.0978"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Hara A, Ohkubo T, Kikuya M, Shintani Y, Obara T, Metoki H, et al. Detection of carotid atherosclerosis in individuals with masked hypertension and white-coat hypertension by self-measured blood pressure at home: the Ohasama study. J Hypertens. 2007;25:321\u20137. https:\/\/doi.org\/10.1097\/HJH.0b013e3280115bbf.","DOI":"10.1097\/HJH.0b013e3280115bbf"},{"key":"23","doi-asserted-by":"publisher","unstructured":"23. Umemura S, Arima H, Arima S, Asayama K, Dohi Y, Hirooka Y, et al. The Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2019). Hypertens Res. 2019;42:1235\u2013481. https:\/\/doi.org\/10.1038\/s41440-019-0284-9.","DOI":"10.1038\/s41440-019-0284-9"},{"key":"24","doi-asserted-by":"publisher","unstructured":"24. ElSayed NA, Aleppo G, Aroda VR, Bannuru RR, Brown FM, Bruemmer D, et al. 2. Classification and Diagnosis of Diabetes: Standards of Care in Diabetes-2023. Diabetes Care. 2023;46:S19\u201340. https:\/\/doi.org\/10.2337\/dc23-S002.","DOI":"10.2337\/dc23-S002"},{"key":"25","doi-asserted-by":"publisher","unstructured":"25. Grundy SM, Stone NJ, Bailey AL, Beam C, Birtcher KK, Blumenthal RS, et al. 2018 AHA\/ACC\/AACVPR\/AAPA\/ABC\/ACPM\/ADA\/AGS\/APhA\/ASPC\/NLA\/PCNA Guideline on the Management of Blood Cholesterol: Executive Summary: A Report of the American College of Cardiology\/American Heart Association Task Force on Clinical Practice Guidelines. J Am Coll Cardiol. 2019;73:3168\u2013209. https:\/\/doi.org\/10.1016\/j.jacc.2018.11.002.","DOI":"10.1016\/j.jacc.2018.11.002"},{"key":"26","doi-asserted-by":"publisher","unstructured":"26. Dick AS, Comer JS, Bayat M, Curtis M, Hayes T, Pruden SM, et al. Meaningful Associations Redux: Quantifying and interpreting effect size in the context of the Adolescent Brain and Cognitive Development study. Dev Cogn Neurosci. 2025;76:101630. https:\/\/doi.org\/10.1016\/j.dcn.2025.101630.","DOI":"10.1016\/j.dcn.2025.101630"},{"key":"27","unstructured":"27. Organization WH. WHO fact sheet on dementia. https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/dementia (2023). Accessed 5 July."},{"key":"28","doi-asserted-by":"crossref","unstructured":"28. OECD. Dementia. In: OECD, editor. Health at a Glance 2021: OECD Indicators. https:\/\/doi.org\/10.1787\/bf0d1884-en. Paris: OECD Publishing; 2021. p. 256\u20137.","DOI":"10.1787\/bf0d1884-en"},{"key":"29","unstructured":"29. Ministry of Health LaWJ. Final Evaluation Report of Health Japan 21 (Second Term). In: Ministry of Health, Labour and Welfare. 2021. https:\/\/www.mhlw.go.jp\/stf\/seisakunitsuite\/bunya\/kenkou_iryou\/kenkou\/kenkounippon21.html. Accessed July 5, 2025."},{"key":"30","doi-asserted-by":"publisher","unstructured":"30. Rahman A, Jackson H, Hristov H, Isaacson RS, Saif N, Shetty T, et al. Sex and Gender Driven Modifiers of Alzheimer\u2019s: The Role for Estrogenic Control Across Age, Race, Medical, and Lifestyle Risks. Front Aging Neurosci. 2019;11:315. https:\/\/doi.org\/10.3389\/fnagi.2019.00315.","DOI":"10.3389\/fnagi.2019.00315"},{"key":"31","doi-asserted-by":"publisher","unstructured":"31. Brinton RD, Yao J, Yin F, Mack WJ, Cadenas E. Perimenopause as a neurological transition state. Nat Rev Endocrinol. 2015;11:393\u2013405. https:\/\/doi.org\/10.1038\/nrendo.2015.82.","DOI":"10.1038\/nrendo.2015.82"},{"key":"32","doi-asserted-by":"publisher","unstructured":"32. Morrison JH, Brinton RD, Schmidt PJ, Gore AC. Estrogen, menopause, and the aging brain: how basic neuroscience can inform hormone therapy in women. J Neurosci. 2006;26:10332\u201348. https:\/\/doi.org\/10.1523\/jneurosci.3369-06.2006.","DOI":"10.1523\/JNEUROSCI.3369-06.2006"},{"key":"33","doi-asserted-by":"publisher","unstructured":"33. Sugiyama N, Barros RP, Warner M, Gustafsson JA. ERbeta: recent understanding of estrogen signaling. Trends Endocrinol Metab. 2010;21:545\u201352. https:\/\/doi.org\/10.1016\/j.tem.2010.05.001.","DOI":"10.1016\/j.tem.2010.05.001"},{"key":"34","doi-asserted-by":"publisher","unstructured":"34. Mitra SW, Hoskin E, Yudkovitz J, Pear L, Wilkinson HA, Hayashi S, et al. Immunolocalization of estrogen receptor beta in the mouse brain: comparison with estrogen receptor alpha. Endocrinology. 2003;144:2055\u201367. https:\/\/doi.org\/10.1210\/en.2002-221069.","DOI":"10.1210\/en.2002-221069"},{"key":"35","doi-asserted-by":"publisher","unstructured":"35. Maioli S, Leander K, Nilsson P, Nalvarte I. Estrogen receptors and the aging brain. Essays Biochem. 2021;65:913\u201325. https:\/\/doi.org\/10.1042\/ebc20200162.","DOI":"10.1042\/EBC20200162"},{"key":"36","doi-asserted-by":"publisher","unstructured":"36. Sundstr\u00f6m Poromaa I, Gingnell M. Menstrual cycle influence on cognitive function and emotion processing-from a reproductive perspective. Front Neurosci. 2014;8:380. https:\/\/doi.org\/10.3389\/fnins.2014.00380.","DOI":"10.3389\/fnins.2014.00380"},{"key":"37","doi-asserted-by":"publisher","unstructured":"37. Storsve AB, Fjell AM, Tamnes CK, Westlye LT, Overbye K, Aasland HW, et al. Differential longitudinal changes in cortical thickness, surface area and volume across the adult life span: regions of accelerating and decelerating change. J Neurosci. 2014;34:8488\u201398. https:\/\/doi.org\/10.1523\/jneurosci.0391-14.2014.","DOI":"10.1523\/JNEUROSCI.0391-14.2014"},{"key":"38","doi-asserted-by":"publisher","unstructured":"38. Lisofsky N, M\u00e5rtensson J, Eckert A, Lindenberger U, Gallinat J, K\u00fchn S. Hippocampal volume and functional connectivity changes during the female menstrual cycle. Neuroimage. 2015;118:154\u201362. https:\/\/doi.org\/10.1016\/j.neuroimage.2015.06.012.","DOI":"10.1016\/j.neuroimage.2015.06.012"},{"key":"39","doi-asserted-by":"publisher","unstructured":"39. Marchant I, Stojanova J, Acevedo L, Olivero P. Estrogen rapid effects: a window of opportunity for the aging brain? Neural Regen Res. 2022;17:1629\u201332. https:\/\/doi.org\/10.4103\/1673-5374.332121.","DOI":"10.4103\/1673-5374.332121"},{"key":"40","unstructured":"40. Ministry of Health LaW. Vital Statistics of Japan 2023. https:\/\/www.mhlw.go.jp\/english\/ (2024). Accessed July 5."},{"key":"41","doi-asserted-by":"publisher","unstructured":"41. Koski-Rahikkala H, Pouta A, Pietil\u00e4inen K, Hartikainen AL. Does parity affect mortality among parous women? J Epidemiol Community Health. 2006;60:968\u201373. https:\/\/doi.org\/10.1136\/jech.2005.044735.","DOI":"10.1136\/jech.2005.044735"},{"key":"42","doi-asserted-by":"publisher","unstructured":"42. Elman C, O\u2019Rand AM, London AS. Parity and post-reproductive mortality among U.S. Black and White women: Evidence from the health and retirement study. PLoS One. 2024;19:e0310629. https:\/\/doi.org\/10.1371\/journal.pone.0310629.","DOI":"10.1371\/journal.pone.0310629"},{"key":"43","doi-asserted-by":"publisher","unstructured":"43. Hosokawa M, Imazeki S, Mizunuma H, Kubota T, Hayashi K. Secular trends in age at menarche and time to establish regular menstrual cycling in Japanese women born between 1930 and 1985. BMC Womens Health. 2012;12:19. https:\/\/doi.org\/10.1186\/1472-6874-12-19.","DOI":"10.1186\/1472-6874-12-19"},{"key":"44","doi-asserted-by":"crossref","unstructured":"44. Li W, Liu Q, Deng X, Chen Y, Liu S, Story M. Association between Obesity and Puberty Timing: A Systematic Review and Meta-Analysis. Int J Environ Res Public Health. 2017;14. https:\/\/doi.org\/10.3390\/ijerph14101266.","DOI":"10.3390\/ijerph14101266"}],"container-title":["Environmental Health and Preventive Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/ehpm\/31\/0\/31_25-00400\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,8]],"date-time":"2026-08-08T05:12:50Z","timestamp":1786165970000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/ehpm\/31\/0\/31_25-00400\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":44,"journal-issue":{"issue":"0","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.1265\/ehpm.25-00400","relation":{},"ISSN":["1342-078X","1347-4715"],"issn-type":[{"value":"1342-078X","type":"print"},{"value":"1347-4715","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]},"article-number":"25-00400"}}