{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T10:13:54Z","timestamp":1789726434454,"version":"4.0.1"},"reference-count":12,"publisher":"International Scientific Information, Inc.","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Case Rep"],"DOI":"10.12659\/ajcr.929002","type":"journal-article","created":{"date-parts":[[2021,2,22]],"date-time":"2021-02-22T11:45:50Z","timestamp":1613994350000},"source":"Crossref","is-referenced-by-count":7,"title":["A 78-Year-Old Man with a Pulmonary Embolism Who Developed Skin Necrosis 7 Days After Treatment with the Direct Oral Anticoagulant Factor Xa Inhibitor Apixaban"],"prefix":"10.12659","volume":"22","author":[{"given":"Tusharkumar","family":"Pansuriya","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Hospital Corporation of America (HCA) Houston Healthcare, Kingwood, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Trung","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Hospital Corporation of America (HCA) Houston Healthcare, Kingwood, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mir Ali","family":"Sadat","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Hospital Corporation of America (HCA) Houston Healthcare, Kingwood, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Syed A.","family":"Raza","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Hospital Corporation of America (HCA) Houston Healthcare, Kingwood, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siva T.","family":"Sarva","sequence":"additional","affiliation":[{"name":"Department of Pulmonary and Critical Care, Hospital Corporation of America (HCA) Houston Healthcare, Kingwood, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4947","published-online":{"date-parts":[[2021,1,25]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.120.017559"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2020001830"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1007\/s40262-019-00775-z"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1111\/jth.12485"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1915103"},{"key":"ref6","first-page":"7234069","volume":"2020","author":"Wade","year":"2020","journal-title":"Case Rep Rheumatol"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2017.12.007"},{"key":"ref8","first-page":"213","volume":"16","author":"Szaflarski","year":"2016","journal-title":"Anatol J Cardiol"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1177\/2042098620937884"},{"key":"ref10","first-page":"173","author":"Page","year":"2019","journal-title":"Europen Journal of Medical Case Reports"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.5021\/ad.2014.26.1.96"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1177\/1203475417716364"}],"container-title":["American Journal of Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.amjcaserep.com\/download\/index\/idArt\/929002","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T11:36:09Z","timestamp":1782560169000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.amjcaserep.com\/abstract\/index\/idArt\/929002"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1,25]]},"references-count":12,"alternative-id":["929002"],"URL":"https:\/\/doi.org\/10.12659\/ajcr.929002","relation":{},"ISSN":["1941-5923"],"issn-type":[{"value":"1941-5923","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,1,25]]}}}