{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T15:55:14Z","timestamp":1758815714187},"reference-count":0,"publisher":"Termedia Sp. z.o.o.","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pol J Radiol"],"abstract":"<jats:p>&lt;b&gt;Background&lt;\/b&gt;: To assess the role of diffusion-weighted MR imaging in differentiation between Graves\u2019 disease and painless thyroiditis. &lt;br \/&gt;\n&lt;b&gt;Material\/Methods&lt;\/b&gt;: A prospective study was conducted among 37 consecutive patients with untreated thyrotoxicosis (25 female and 12 male; mean age of 44 years) and 15 age- and sex-matched controls. Diffusion- weighted MR imaging of the thyroid gland was performed in patients and controls. The apparent diffusion coefficient (ADC) value of the thyroid gland was calculated and correlated with Tc-99m uptake and thyroid function tests of the patients. &lt;br \/&gt;\n&lt;b&gt;Results&lt;\/b&gt;: There was a significant difference in the ADC value of the thyroid gland between patients and the control group (P=0.001). The mean ADC value of the thyroid gland in Graves\u2019 disease was 2.03\u00b10.28\u00d710\u20133 mm2\/sec, and in patients with painless thyroiditis 1.46\u00b10.22\u00d710\u20133 mm2\/sec, respectively. There was a significant difference in the ADC values between Graves\u2019 disease and painless thyroiditis (P=0.001). When the ADC value of 1.45\u00d710\u20133 mm2\/sec was used as a threshold value for differentiating Graves\u2019 disease from painless thyroiditis, the best result was obtained with area under the curve of 0.934, accuracy of 83.8%, sensitivity of 95.8%, and specificity of 61.5%. The mean ADC value of the thyroid gland in patients positively correlated with serum TRAb and Tc-99m uptake (r=0.57, P=0.001 and r=0.74, P=0.001, respectively). &lt;br \/&gt;\n&lt;b&gt;Conclusions&lt;\/b&gt;: We concluded that ADC values of the thyroid gland can be used to differentiate Graves\u2019 disease from painless thyroiditis in patients with untreated thyrotoxicosis.<\/jats:p>","DOI":"10.12659\/pjr.902416","type":"journal-article","created":{"date-parts":[[2018,3,6]],"date-time":"2018-03-06T16:51:11Z","timestamp":1520355071000},"page":"536-541","source":"Crossref","is-referenced-by-count":12,"title":["Role of Diffusion-Weighted Magnetic Resonance (MR) Imaging in Differentiation Between Graves\u2019 Disease and Painless Thyroiditis"],"prefix":"10.5114","volume":"82","author":[{"given":"Ahmed Abdel Khalek Abdel","family":"Razek","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sieza Samir Abd","family":"Allah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amr Abd El-hamid","family":"El-Said","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3061","published-online":{"date-parts":[[2018,2,2]]},"container-title":["Polish Journal of Radiology"],"original-title":[],"link":[{"URL":"https:\/\/www.polradiol.com\/pdf-187495-108605","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.polradiol.com\/pdf-187495-108605","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,22]],"date-time":"2024-05-22T11:32:45Z","timestamp":1716377565000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.polradiol.com\/Role-of-Diffusion-Weighted-Magnetic-Resonance-MR-Imaging-in-Differentiation-Between,187495,0,2.html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,2,2]]},"references-count":0,"alternative-id":["187495"],"URL":"https:\/\/doi.org\/10.12659\/pjr.902416","relation":{},"ISSN":["1899-0967"],"issn-type":[{"value":"1899-0967","type":"print"}],"subject":[],"published":{"date-parts":[[2018,2,2]]}}}