{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,10]],"date-time":"2026-05-10T01:08:34Z","timestamp":1778375314113,"version":"3.51.4"},"reference-count":0,"publisher":"Pakistan Journal of Medical Sciences","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pak J Med Sci"],"abstract":"<jats:p>Objective: To determine the efficacy of terlipressin and albumin in improving renal functions in patient with hepatorenal syndrome (HRS) and to identify factors determinant of better response.Methods: In this quasi experimental interventional study patients of liver cirrhosis and ascites with HRS type I were treated with intravenous albumin and incremental dosage of terlipressin based on response with maximum dose of 12mg\/day. Decline of creatinine below 1.5mg\/dl was defined as complete response. Factors predictive of response to therapy were determined via linear regression analysis.Results: Twenty four patients were included with male to female ratio<\/jats:p>","DOI":"10.12669\/pjms.322.9315","type":"journal-article","created":{"date-parts":[[2016,3,16]],"date-time":"2016-03-16T06:14:43Z","timestamp":1458108883000},"source":"Crossref","is-referenced-by-count":1,"title":["Hepatorenal syndrome: Response to terlipressinand albumin and its determinants"],"prefix":"10.12669","volume":"32","author":[{"given":"Shahid","family":"Sarwar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anwaar A.","family":"Khan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4935","published-online":{"date-parts":[[2016,3,24]]},"container-title":["Pakistan Journal of Medical Sciences"],"original-title":[],"link":[{"URL":"https:\/\/pjms.org.pk\/index.php\/pjms\/article\/download\/18575\/7773","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/pjms.org.pk\/index.php\/pjms\/article\/download\/18575\/7773","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,10]],"date-time":"2026-05-10T00:14:41Z","timestamp":1778372081000},"score":1,"resource":{"primary":{"URL":"https:\/\/pjms.org.pk\/index.php\/pjms\/article\/view\/18575"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,3,24]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2016,3,22]]}},"URL":"https:\/\/doi.org\/10.12669\/pjms.322.9315","relation":{},"ISSN":["1681-715X","1682-024X"],"issn-type":[{"value":"1681-715X","type":"electronic"},{"value":"1682-024X","type":"print"}],"subject":[],"published":{"date-parts":[[2016,3,24]]}}}