{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T07:09:23Z","timestamp":1778310563551,"version":"3.51.4"},"reference-count":0,"publisher":"Pakistan Journal of Medical Sciences","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pak J Med Sci"],"abstract":"<jats:p>Objective: This research was designed to investigate the prognostic determinants of patients with traumatic brain injury (TBI) undergoing decompressive craniectomy (DC).\r\nMethods: The present study was a retrospective single center research including a total of 112 patients undergoing DC for TBI in Liaocheng People\u2019s Hospital between January 2017 and December 2018. The results were measured by Extended Glasgow Outcome Sale (GOSE). The\u00a0prognostic determinants were identified by univariate and binary logistic regression analysis between the deaths and survivors or favorable and unfavorable outcomes.\r\nResults: At the six-month follow-up, the mortality was 45.5% including 37 (33.0%) patients died within 30 days. The independent prognostic factors of 30-day mortality were age (p=0.033), D-dimer level at admission (p=0.032) and postoperative hypernatremia (p=0.014). Seventy five patients survived more than 30 days after DC, among which 27 (36.0%) patients had unfavorable prognosis\u00a0(GOSE 1-4)\u00a0and 48 (64.0%) patients presented favorable prognosis (GOSE\u00a05-8). After\u00a030 days from DC, the occurrence of post-traumatic hydrocephalus(PTH) (p= 0.008) was associated with unfavorable prognosis.\r\nConclusions: Although DC is an effective treatment for TBI patients, the mortality and morbidity risk remain high. A combination of age, D-dimer level at admission and postoperative hypernatremia may be a good prognostic factor for 30-day mortality. Developing an accurate therapy strategy to prevent and control PTH may be beneficial to the 6-month prognosis for TBI patients undergoing DC.\r\ndoi: https:\/\/doi.org\/10.12669\/pjms.36.4.2045\r\nHow to cite this:Jiang H, Hao G, Zhang R, Pang Q. Determinants affecting the prognosis of decompressive craniectomy for traumatic brain injury. Pak J Med Sci. 2020;36(4):770-775. doi: https:\/\/doi.org\/10.12669\/pjms.36.4.2045\r\nThis is an Open Access article distributed under the terms of the Creative Commons Attribution License (http:\/\/creativecommons.org\/licenses\/by\/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.<\/jats:p>","DOI":"10.12669\/pjms.36.4.2045","type":"journal-article","created":{"date-parts":[[2020,4,15]],"date-time":"2020-04-15T07:10:58Z","timestamp":1586934658000},"source":"Crossref","is-referenced-by-count":2,"title":["Determinants affecting the prognosis of decompressive\u00a0craniectomy for traumatic brain injury"],"prefix":"10.12669","volume":"36","author":[{"given":"Haitao","family":"Jiang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guangshan","family":"Hao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rui","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qi","family":"Pang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4935","published-online":{"date-parts":[[2020,5,14]]},"container-title":["Pakistan Journal of Medical Sciences"],"original-title":[],"link":[{"URL":"https:\/\/pjms.org.pk\/index.php\/pjms\/article\/download\/2045\/486","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/pjms.org.pk\/index.php\/pjms\/article\/download\/2045\/486","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T06:11:59Z","timestamp":1778307119000},"score":1,"resource":{"primary":{"URL":"https:\/\/pjms.org.pk\/index.php\/pjms\/article\/view\/2045"}},"subtitle":["Study on decompressive craniectomy for traumatic brain injury"],"short-title":[],"issued":{"date-parts":[[2020,5,14]]},"references-count":0,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2020,4,15]]}},"URL":"https:\/\/doi.org\/10.12669\/pjms.36.4.2045","relation":{},"ISSN":["1681-715X","1682-024X"],"issn-type":[{"value":"1681-715X","type":"electronic"},{"value":"1682-024X","type":"print"}],"subject":[],"published":{"date-parts":[[2020,5,14]]}}}