{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T13:11:07Z","timestamp":1778332267735,"version":"3.51.4"},"reference-count":0,"publisher":"Pakistan Journal of Medical Sciences","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pak J Med Sci"],"abstract":"<jats:p>Objective: To analyze the value of serum human chorionic gonadotropin (\u03b2-HCG), anti-Mullerian hormone (AMH), progesterone (P)\/ estradiol (E2) in predicting the pregnancy outcome of frozen-thawed embryo transfer (FET) cycle in patients with low profile endometrium.\r\nMethods: In this retrospective study, 120 patients with low-profile endometrium who received FET therapy in the reproductive center of Maternity &amp; Child Care Center of Qinhuangdao from October 2019 to February 2023 were included. Serum \u03b2-HCG, AMH, and P\/E2 levels were measured on the day of FET transplantation. After 30 days they were divided into pregnancy group and non-pregnancy group according to whether they were pregnant. The risk factors affecting the cycle pregnancy rate of FET were analyzed. The values of \u03b2-HCG, AMH, P\/E2 and the combination of the three in predicting the periodic pregnancy rate of FET in patients were analyzed.\r\nResults: Logistic regression analysis showed that age (\u226535 years), type of infertility (primary infertility), transplanted fetus, moderate and severe intrauterine adhesions and P, P\/E2 levels were risk factors for the periodic pregnancy rate of FET (OR &gt; 1, P&lt;0.05). The ROC curve showed that the AUC of serum \u03b2-HCG, AMH, P\/E2 and their combination to predict the pregnancy rate of FET cycle in patients with thin endometrium was 0.83(95%CI:0.741-0.910), 0.86(95%CI:0.788-0.922), 0.75(95%CI:0.662-0.838), and 0.88(95%CI:0.807-0.947).\r\nConclusion: Serum \u03b2-HCG, AMH, and P\/E2 are closely related to the cycle pregnancy rate of FET in patients with thin endometrium. Therefore, dynamic monitoring of the changes of three indicators should be conducted clinically.\r\ndoi: https:\/\/doi.org\/10.12669\/pjms.41.4.9980\r\nHow to cite this: Yan Y, Zhang J, Li W, Yin X. Value analysis of serum \u03b2 -HCG, AMH, and P\/E2 for predicting freeze-thaw embryo transfer outcomes in patients with thin endometrium. Pak J Med Sci. 2025;41(4):973-978. doi: https:\/\/doi.org\/10.12669\/pjms.41.4.9980\r\nThis is an Open Access article distributed under the terms of the Creative Commons Attribution License (http:\/\/creativecommons.org\/licenses\/by\/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.<\/jats:p>","DOI":"10.12669\/pjms.41.4.9980","type":"journal-article","created":{"date-parts":[[2025,3,27]],"date-time":"2025-03-27T18:55:38Z","timestamp":1743101738000},"page":"973-978","source":"Crossref","is-referenced-by-count":3,"title":["Value analysis of serum \u03b2 -HCG, AMH, and P\/E2 for predicting freeze-thaw embryo transfer outcomes in patients with thin endometrium"],"prefix":"10.12669","volume":"41","author":[{"given":"Yani","family":"Yan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weiwei","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiurong","family":"Yin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4935","published-online":{"date-parts":[[2025,3,27]]},"container-title":["Pakistan Journal of Medical Sciences"],"original-title":[],"link":[{"URL":"https:\/\/pjms.org.pk\/index.php\/pjms\/article\/download\/9980\/2695","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/pjms.org.pk\/index.php\/pjms\/article\/download\/9980\/2695","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T12:39:40Z","timestamp":1778330380000},"score":1,"resource":{"primary":{"URL":"https:\/\/pjms.org.pk\/index.php\/pjms\/article\/view\/9980"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,27]]},"references-count":0,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2025,3,27]]}},"URL":"https:\/\/doi.org\/10.12669\/pjms.41.4.9980","relation":{},"ISSN":["1681-715X","1682-024X"],"issn-type":[{"value":"1681-715X","type":"electronic"},{"value":"1682-024X","type":"print"}],"subject":[],"published":{"date-parts":[[2025,3,27]]}}}