{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T10:39:29Z","timestamp":1781606369836,"version":"3.54.5"},"reference-count":0,"publisher":"Pakistan Journal of Medical Sciences","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pak J Med Sci"],"abstract":"<jats:p>Objective: The study assessed differences in the thyroglobulin antibody and thyroid peroxidase antibody between euthyroid Type-I and Type-II diabetes mellitus (DM) and control groups not using thyroid medication.\r\nMethods: This was a cross-sectional study. People with Type-I and Type-II diabetes and a control group aged between 18 and 80 years were enrolled at the diabetes and internal medicine outpatient clinic of Istanbul Haydarpa\u015fa Numune Training and Research Hospital between 2020-2023. Data analysis was performed on 103 participants with Type-I DM, 110 with Type-II DM, and 110 control subjects, all randomly selected. Anti-thyroglobulin antibody (anti-TG), anti-thyroperoxidase antibody (anti-TPO), thyroid-stimulating hormone (TSH), fasting blood glucose (FBG), hemoglobin A1c, (HbA1c) and blood creatinine levels were recorded for analysis.\r\nResults: In the study, anti-TG and anti-TPO levels were higher in Type-I DM patients than in the control and Type-II DM groups. This elevation was statistically significant in women with Type-I DM compared to women patients in other groups. In this study, thyroid antibody levels in patients with Type-II DM were not significantly higher than those in the control group.\r\nConclusions: This study highlights the importance of regular assessment of thyroid function and antibodies in women diagnosed with Type-I DM, but not necessarily in those with Type-II DM without thyroid disease.\r\ndoi: https:\/\/doi.org\/10.12669\/pjms.41.7.11918\r\nHow to cite this: Dayan A, Yonak AK. Assessment of Serum Thyroid Antibody Levels in Patients with Type-I and Type-II Diabetes without Thyroid Disease. Pak J Med Sci. 2025;41(7):1996-2002. doi: https:\/\/doi.org\/10.12669\/pjms.41.7.11918\r\nThis is an Open Access article distributed under the terms of the Creative Commons Attribution License (http:\/\/creativecommons.org\/licenses\/by\/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.<\/jats:p>","DOI":"10.12669\/pjms.41.7.11918","type":"journal-article","created":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T18:31:37Z","timestamp":1751481097000},"page":"1996-2002","source":"Crossref","is-referenced-by-count":1,"title":["Assessment of Serum Thyroid Antibody Levels in Patients with Type-I and Type-II Diabetes without Thyroid Disease"],"prefix":"10.12669","volume":"41","author":[{"given":"Ak\u0131n","family":"Dayan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8076-7783","authenticated-orcid":false,"given":"Asl\u0131","family":"Karadeniz Y\u00f6nak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4935","published-online":{"date-parts":[[2025,7,2]]},"container-title":["Pakistan Journal of Medical Sciences"],"original-title":[],"link":[{"URL":"https:\/\/pjms.org.pk\/index.php\/pjms\/article\/download\/11918\/2865","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/pjms.org.pk\/index.php\/pjms\/article\/download\/11918\/2865","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T13:48:31Z","timestamp":1778334511000},"score":1,"resource":{"primary":{"URL":"https:\/\/pjms.org.pk\/index.php\/pjms\/article\/view\/11918"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,2]]},"references-count":0,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2025,6,30]]}},"URL":"https:\/\/doi.org\/10.12669\/pjms.41.7.11918","relation":{},"ISSN":["1681-715X","1682-024X"],"issn-type":[{"value":"1681-715X","type":"electronic"},{"value":"1682-024X","type":"print"}],"subject":[],"published":{"date-parts":[[2025,7,2]]}}}