{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T14:09:20Z","timestamp":1778335760439,"version":"3.51.4"},"reference-count":0,"publisher":"Pakistan Journal of Medical Sciences","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pak J Med Sci"],"abstract":"<jats:p>Objective: To determine the success rate, frequency of complications and, side effects of misoprostol used, for second-trimester miscarriages, in women with history of previous cesarean section.\nMethodology: This cross sectional study was done at Lady Reading Hospital, Peshawar, from January 2021 to December 2022.The sample included 90 women, with a history of previous one cesarean section, undergoing medical management of second-trimester miscarriage. Outcomes noted were, success rate, frequency of scar complications and side effects.\nResults: The mean age of sample of 90 patients, was 28.87\u00b14.6. The mean induction to expulsion time was 11 hours \u00b1 3.9. Complete expulsion was achieved in 67.7% (61\/90) cases. The need for surgical evacuation of retained products of conception, was observed in 32.5% (29\/90) of cases. Scar complications were noted in 2.2% (2\/90) cases. The need for surgical evacuation was more common with the vaginal route of administration as compared to the sublingual route i.e. 50% (20\/40) vs 18% (09\/50), p-0.001. Diarrhea was significantly associated with sublingual route of administration, p-0.001. Fever was common with the vaginal route, 47.5% (19\/40) vs 26% (13\/50), p-0.03. The mean induction to termination time was significantly shorter in the sublingual route group. (p-0.001)\nConclusion: Misoprostol successfully and safely concludes the process of second trimester miscarriage in carefully selected women with a history of previous one cesarean birth.<\/jats:p>","DOI":"10.12669\/pjms.41.8.10884","type":"journal-article","created":{"date-parts":[[2025,8,12]],"date-time":"2025-08-12T04:37:07Z","timestamp":1754973427000},"page":"2201-2205","source":"Crossref","is-referenced-by-count":0,"title":["An experience with the use of Misoprostol in second trimester miscarriages, in women with prior cesarean births"],"prefix":"10.12669","volume":"41","author":[{"given":"Nazia","family":"Liaqat","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qudsia","family":"Qazi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fazeela","family":"Gul","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4935","published-online":{"date-parts":[[2025,8,2]]},"container-title":["Pakistan Journal of Medical Sciences"],"original-title":[],"link":[{"URL":"https:\/\/pjms.org.pk\/index.php\/pjms\/article\/download\/10884\/2925","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/pjms.org.pk\/index.php\/pjms\/article\/download\/10884\/2925","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T13:10:50Z","timestamp":1778332250000},"score":1,"resource":{"primary":{"URL":"https:\/\/pjms.org.pk\/index.php\/pjms\/article\/view\/10884"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,2]]},"references-count":0,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2025,8,1]]}},"URL":"https:\/\/doi.org\/10.12669\/pjms.41.8.10884","relation":{},"ISSN":["1681-715X","1682-024X"],"issn-type":[{"value":"1681-715X","type":"electronic"},{"value":"1682-024X","type":"print"}],"subject":[],"published":{"date-parts":[[2025,8,2]]}}}