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(2021) Sphingosine 1-phosphate (S1P) produced by sphingosine kinase 1 (SphK1) and exported via ABCC1 is related to hepatocellular carcinoma (HCC) progression. Am. J. Cancer Res. 11; 4394\u20134407."},{"key":"43","doi-asserted-by":"crossref","unstructured":"43 Serriere-Lanneau, V., Teixeira-Clerc, F., Li, L., Schippers, M., de Wries, W., Julien, B., et al. (2007) The sphingosine 1-phosphate receptor S1P2 triggers hepatic wound healing. FASEB J. 21; 2005\u20132013.","DOI":"10.1096\/fj.06-6889com"},{"key":"44","doi-asserted-by":"crossref","unstructured":"44 Srisowanna, N., Choijookhuu, N., Yano, K., Batmunkh, B., Ikenoue, M., Nhat Huynh Mai, N., et al. (2019) The Effect of Estrogen on Hepatic Fat Accumulation during Early Phase of Liver Regeneration after Partial Hepatectomy in Rats. Acta Histochem. Cytochem. 52; 67\u201375.","DOI":"10.1267\/ahc.19018"},{"key":"45","doi-asserted-by":"crossref","unstructured":"45 Sugita, N., Choijookhuu, N., Yano, K., Lee, D., Ikenoue, M., Fidya, et al. (2021) Depletion of high-mobility group box 2 causes seminiferous tubule atrophy via aberrant expression of androgen and estrogen receptors in mouse testis\u2020. Biol. Reprod. 105; 1510\u20131520.","DOI":"10.1093\/biolre\/ioab187"},{"key":"46","doi-asserted-by":"crossref","unstructured":"46 Sydor, S., Gu, Y., Schlattjan, M., Bechmann, L. P., Rauen, U., Best, J., et al. (2013) Steatosis does not impair liver regeneration after partial hepatectomy. Lab. Invest. 93; 20\u201330.","DOI":"10.1038\/labinvest.2012.142"},{"key":"47","doi-asserted-by":"crossref","unstructured":"47 Taguchi, R., Yamaguchi-Tanaka, M., Takagi, K., Sato, A., Miki, Y., Miyashita, M., et al. (2024) Clinicopathological Significance and Prognostic Role of High Mobility Group Box 1 (HMGB1), Toll-Like Receptor (TLR) 2 and TLR4 in Breast Cancer. Acta Histochem. Cytochem. 57; 75\u201383.","DOI":"10.1267\/ahc.24-00006"},{"key":"48","doi-asserted-by":"crossref","unstructured":"48 Tokushige, K. (2024) New concept in fatty liver diseases. Hepatol. Res. 54; 125\u2013130.","DOI":"10.1111\/hepr.14004"},{"key":"49","doi-asserted-by":"crossref","unstructured":"49 Vetelainen, R., van Vliet, A. K. and van Gulik, T. M. (2007) Severe steatosis increases hepatocellular injury and impairs liver regeneration in a rat model of partial hepatectomy. Ann. Surg. 245; 44\u201350.","DOI":"10.1097\/01.sla.0000225253.84501.0e"},{"key":"50","doi-asserted-by":"crossref","unstructured":"50 Yagi, S., Hirata, M., Miyachi, Y. and Uemoto, S. (2020) Liver Regeneration after Hepatectomy and Partial Liver Transplantation. Int. J. Mol. Sci. 21; 8414.","DOI":"10.3390\/ijms21218414"},{"key":"51","doi-asserted-by":"crossref","unstructured":"51 Yamaguma, Y., Sugita, N., Choijookhuu, N., Yano, K., Lee, D., Ikenoue, M., et al. (2022) Crucial role of high-mobility group box 2 in mouse ovarian follicular development through estrogen receptor beta. Histochem. 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