{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T05:05:48Z","timestamp":1772168748065,"version":"3.50.1"},"update-to":[{"DOI":"10.12688\/f1000research.109007.1","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T00:00:00Z","timestamp":1694563200000}},{"DOI":"10.12688\/f1000research.109007.2","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T00:00:00Z","timestamp":1694563200000}}],"reference-count":15,"publisher":"F1000 Research Ltd","license":[{"start":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T00:00:00Z","timestamp":1694563200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["f1000research.com"],"crossmark-restriction":false},"short-container-title":["F1000Res"],"abstract":"<ns3:p>Background: The global pandemic of SARS-CoV-2, or COVID-19 continues to attack all human systems. Although COVID-19 is a respiratory disease, various extra-pulmonary manifestations, including musculoskeletal and neuropathies\/myopathies was reported. This study aimed to investigates the long-term impacts of COVID-19 infection on physical health, capability of daily life activities, musculoskeletal and neurological functions in the Kingdom of Saudi Arabia (KSA). Methods: A total of 499 adults recovered from COVID-19 infection of both sexes, who resided in the KSA were recruited randomly and invited to participate in this cross-sectional web-based survey. A self-administered structured questionnaire was used as an instrument of data collection. All respondents returned the questionnaire. Their responses were recorded, stored into a Microsoft Excel sheet 2010 and analyzed with the Statistical Package for the Social Sciences (SPSS) version 24. Percentages were used to convey descriptive data. The percentages were presented with a 95% confidence interval (CI). For statistical significance, a 0.05 p-value was used. Results: The overall prevalence of neurological and musculoskeletal disorders as follows: headache (63.1%), muscle ache or weakness (62.3%), vertigo (25%), concentration problems (21.8%), breathing troubles (20.4%), loss of balance (19.4%), seizure (1%), and Guillain-Barre Syndrome (0.6%). The results also revealed a significant association between the influence of COVID-19 infection and daily activities, gender and respiratory disorders. Conclusion: The findings highlighted and concluded that COVID-19 infection had an impact on respiratory, nervous, musculoskeletal systems and affect daily activities.<\/ns3:p>","DOI":"10.12688\/f1000research.109007.3","type":"journal-article","created":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T06:45:18Z","timestamp":1694587518000},"page":"463","update-policy":"https:\/\/doi.org\/10.12688\/f1000research.crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Prevalence of Musculoskeletal, Neurological and Physical Disorder After COVID-19 in Saudi Arabia: A Cross Sectional Study"],"prefix":"10.12688","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9352-4916","authenticated-orcid":false,"given":"Hayam","family":"Mahmoud","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6299-4480","authenticated-orcid":false,"given":"Anwar","family":"Ebid","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammed","family":"Alghamdi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9106-520X","authenticated-orcid":false,"given":"Abeer","family":"Ibrahim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed","family":"Almoosa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2560","published-online":{"date-parts":[[2023,9,13]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"514-523","DOI":"10.1016\/S0140-6736(20)30154-9","article-title":"A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster.","volume":"395","author":"J Chan","year":"2020 Feb 15","journal-title":"Lancet."},{"key":"ref2","doi-asserted-by":"publisher","first-page":"1202-1216","DOI":"10.4236\/health.2020.129088 370","article-title":"Tackling SARS-CoV-2 Pandemic: The Way Forward.","volume":"12","author":"S Tabish","year":"September 25, 2020","journal-title":"Health."},{"key":"ref3","doi-asserted-by":"publisher","first-page":"112-119","DOI":"10.4067\/S0718-381X2022000100112","article-title":"Clinical signs and symptoms associated with COVID-19: a cross sectional study.","volume":"16","author":"C Romero","year":"2022","journal-title":"International Journal of Odontostomatology."},{"key":"ref4","doi-asserted-by":"publisher","first-page":"281-286","DOI":"10.1007\/s12098-020-03263-6","article-title":"A Review of Coronavirus Disease-2019 (COVID-19).","volume":"87","author":"T Singhal","year":"2020 Apr","journal-title":"Indian Journal of Pediatrics."},{"key":"ref5","doi-asserted-by":"publisher","first-page":"7302","DOI":"10.3390\/ijerph17197302","article-title":"Impact of COVID-19Quarantine on Low Back Pain Intensity, Prevalence, and Associated Risk Factors among Adult Citizens Residing in Riyadh (Saudi Arabia): A Cross-Sectional Study.","volume":"17","author":"P \u0160ag\u00e1t","year":"2020 Oct 6","journal-title":"International Journal of Environmental Research and Public Health."},{"key":"ref7","doi-asserted-by":"publisher","first-page":"339-341","DOI":"10.1038\/d41586-020-02598-6","article-title":"The lasting misery of coronavirus long-haulers.","volume":"585","author":"M Marshall","year":"2020, September 14","journal-title":"Nature."},{"key":"ref8","doi-asserted-by":"publisher","first-page":"506","DOI":"10.3389\/fpubh.2020.00506","article-title":"Epidemiology of COVID-19 in the Kingdom of Saudi Arabia: An Ecological Study.","volume":"8","author":"M Alyami","year":"2020 Sep 17","journal-title":"Frontiers in Public Health."},{"key":"ref9","article-title":"Household Sports Practice Survey Bulletin 2019.","year":"2019","journal-title":"General Authority for Statistics."},{"key":"ref10","doi-asserted-by":"publisher","first-page":"7302","DOI":"10.3390\/ijerph17197302","article-title":"Impact of COVID-19Quarantine on Low Back Pain Intensity, Prevalence, and Associated Risk Factors among Adult Citizens Residing in Riyadh (Saudi Arabia): A Cross-Sectional Study.","volume":"17","author":"P \u0160ag\u00e1t","year":"2020 Oct 6","journal-title":"International Journal of Environmental Research and Public Health."},{"key":"ref11","doi-asserted-by":"publisher","first-page":"1487","DOI":"10.1186\/s12889-021-11540-y","article-title":"The impact of COVID-19 quarantines on dietary habits and physical activity in Saudi Arabia: a cross-sectional study.","volume":"21","author":"M Bakhsh","year":"2021","journal-title":"BMC Public Health."},{"key":"ref12","doi-asserted-by":"publisher","first-page":"687","DOI":"10.3389\/fneur.2020.00687","article-title":"Neurological and Musculoskeletal Features of COVID-19: A Systematic Review and Meta-Analysis.","volume":"11","author":"A Abdullahi","year":"2020 Jun 26","journal-title":"Frontiers in Neurology."},{"key":"ref13","doi-asserted-by":"publisher","first-page":"00542-02020","DOI":"10.1183\/23120541.00542-2020","article-title":"Persistent symptoms 3 months after a SARS-CoV-2 infection: the post-COVID-19 syndrome?.","volume":"6","author":"Y Go\u00ebrtz","year":"2020 Oct 26","journal-title":"ERJ Open Research."},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph17249419","article-title":"Psychological Health and Physical Activity Levels during the COVID-19 Pandemic: A Systematic Review.","volume":"17","author":"V Violant-Holz","year":"2020 Dec","journal-title":"International Journal of Environmental Research and Public Health."},{"key":"ref15","doi-asserted-by":"publisher","first-page":"e924085","DOI":"10.12659\/MSMBR.924085","article-title":"Analysis of Psychological and Sleep Status and Exercise Rehabilitation of Front-Line Clinical Staff in the Fight Against COVID-19 in China.","volume":"26","author":"K Wu","year":"2020 May 11","journal-title":"Medical Science Monitor Basic Research."},{"key":"ref16","doi-asserted-by":"publisher","first-page":"205-212","DOI":"10.1186\/s12933-020-01184-4","article-title":"Diabetes and Covid-19 among hospitalized patients in Saudi Arabia: a single-centre retrospective study.","volume":"19","author":"A Alguwaihes","year":"2020","journal-title":"Cardiovascular Diabetology, [s. l.]."}],"container-title":["F1000Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/f1000research.com\/articles\/11-463\/v3\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/f1000research.com\/articles\/11-463\/v3\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/f1000research.com\/articles\/11-463\/v3\/iparadigms","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,13]],"date-time":"2024-09-13T23:20:50Z","timestamp":1726269650000},"score":1,"resource":{"primary":{"URL":"https:\/\/f1000research.com\/articles\/11-463\/v3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9,13]]},"references-count":15,"URL":"https:\/\/doi.org\/10.12688\/f1000research.109007.3","relation":{"has-version":[{"id-type":"doi","id":"10.12688\/f1000research.109007.2","asserted-by":"subject"},{"id-type":"doi","id":"10.12688\/f1000research.109007.1","asserted-by":"subject"}],"has-review":[{"id-type":"doi","id":"10.5256\/f1000research.155834.r206197","asserted-by":"subject"},{"id-type":"doi","id":"10.5256\/f1000research.155834.r206197","asserted-by":"object"}]},"ISSN":["2046-1402"],"issn-type":[{"value":"2046-1402","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,9,13]]},"assertion":[{"value":"Indexed","URL":"https:\/\/f1000research.com\/articles\/11-463\/v3#article-reports","order":0,"name":"referee-status","label":"Referee status","group":{"name":"current-referee-status","label":"Current Referee Status"}},{"value":"10.5256\/f1000research.120457.r143364, Salah Abd Elmonem Sawan, Department of Physical Therapy for Neuromuscular Disorder and its Surgery, Faculty of Physical Therapy, Cairo University, Giza, 01 Aug 2022, version 1, 1 approved","URL":"https:\/\/f1000research.com\/articles\/11-463\/v1#referee-response-143364","order":0,"name":"referee-response-143364","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"<b>Anwar Ebid<\/b>; \n<i>Posted: 09 Aug 2022<\/i>; Dear Professor, Salah Sawan  Thank you so much for your comments.  The authors are grateful for the reviewers' voluntary contributions in the form of insightful comments that have assisted us in improving our manuscript.  The authors have made every effort to revise the manuscript in response to your comments.  In response to your suggestions, we have published an updated version of this article.  Please consider these new versions to be the revised version of this article.  Thank you very much.  Regards,  Authors  The paper is valuable and it is clear, simple, and with good sound but I have some questions and I need the answers from the authors:  1. How could they assure that the link they sent for the patients was only for Saudi people?&nbsp;i.e., Is it possible to provide the reader with a simple explanation of how to send the query to Saudis only, that is, how can you ensure that the link sent was answered by Saudis only because you made this query for Saudis only?  \n<b>Reply: The King Abdullah International Medical Research Center (KAIMRC) was in responsible of selecting Saudi participants at random using a filing system and distributing the questionnaire via WhatsApp.<\/b>  2.&nbsp;How was the query carried out, and how were the questions added?&nbsp;Have you hired a specialist to review the questions about the questionnaire?&nbsp;Was it approved and reviewed by a&nbsp;specialized&nbsp;authority? If you have, please add this to the paper in the methodology&nbsp;section.  \n<b>Reply: The research team first prepared the query, which was then sent to two different Arabic specialists to modify and correct any Arabic errors before being sent to a documented English translation office to prepare the final version of the questionnaire. It was reviewed by the ethical committee in The King Abdullah International Medical Research Center (KAIMRC). The questionnaire was submitted as a preliminary sample to see if there were any issues with it. The response was added to the methodology section.<\/b>  3. Was the&nbsp;survey&nbsp;(Questionnaire) provided in&nbsp;Arabic&nbsp;language or in another language?  \n<b>Reply: Yes: The survey was provided in Arabic and English version after reviewing by specialists, also it was reviewed by the ethical committee in The King Abdullah International Medical Research Center (KAIMRC)<\/b>  4. Are there any further symptoms&nbsp;following&nbsp;COVID-19 were not mentioned at the paper?  \n<b>Reply: All symptoms following&nbsp;COVID-19 mentioned with the respondent were reported in the paper<\/b>  5.&nbsp;Were there another symptoms specific to people who have been vaccinated against the Coronavirus at this work?  \n<b>Reply No: &nbsp;There were no symptoms specific to people who had been vaccinated against the Coronavirus at this work. The questionnaire was only used to assess and collect symptoms after Covid-19, and we did not test for vaccine effect.<\/b>","URL":"https:\/\/f1000research.com\/articles\/11-463\/v3#referee-comment-8628","order":1,"name":"referee-comment-8628","label":"Referee Comment","group":{"name":"article-reports","label":"Article Reports"}},{"value":"10.5256\/f1000research.155834.r206197, Camelia Pescaru, University of Medicine, Timi\u0219oara, 14 Sep 2024, version 3, indexed","URL":"https:\/\/f1000research.com\/articles\/11-463\/v3#referee-response-206197","order":2,"name":"referee-response-206197","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"This work was funded by the Ministry of education in Saudi Arabia (Project number: 20-UQU-IF-P1-001). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.","order":3,"name":"grant-information","label":"Grant Information"},{"value":"This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.","order":0,"name":"copyright-info","label":"Copyright"}]}}