{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T05:05:49Z","timestamp":1772168749754,"version":"3.50.1"},"reference-count":12,"publisher":"F1000 Research Ltd","license":[{"start":{"date-parts":[[2017,3,23]],"date-time":"2017-03-23T00:00:00Z","timestamp":1490227200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["f1000research.com"],"crossmark-restriction":false},"short-container-title":["F1000Res"],"abstract":"<ns4:p>Recently, a few case reports and clinical studies have been published that explore the association of Beh\u00e7et\u2019s Disease (BD) and vitiligo, with conflicting results. Genetic and immunological properties of BD and presence of autoantibodies support autoimmunity, but clinical features suggest autoinflammatory diseases. BD is thought to be a cornerstone between autoimmune and autoinflammatory diseases. On the other hand, vitiligo has been accepted as an autoimmune disease with associations of other autoimmune disorders and there is a possible role of autoimmunity in pathogenesis of the disease. Significant advances have been made understanding the pathogenesis and genetics of BD. However, it is worth presenting rare clinical variants for improving the clinical understanding of BD. Herein, we are presenting a case with diagnosis of both Beh\u00e7et\u2019s disease and vitiligo in same patient, which is a rare occurrence. Discussion and demonstrating the association of these two diseases may give rise to understanding similar and different aspects of autoimmunity and autoinflammatory pathogenesis of both diseases.<\/ns4:p>","DOI":"10.12688\/f1000research.11025.1","type":"journal-article","created":{"date-parts":[[2017,3,23]],"date-time":"2017-03-23T10:51:18Z","timestamp":1490266278000},"page":"310","update-policy":"https:\/\/doi.org\/10.12688\/f1000research.crossmark-policy","source":"Crossref","is-referenced-by-count":4,"title":["Case Report: Beh\u00e7et\u2019s disease accompanied with vitiligo"],"prefix":"10.12688","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9269-2619","authenticated-orcid":false,"given":"Rag\u0131p","family":"Erta\u015f","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kemal","family":"\u00d6zyurt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"At\u0131l","family":"Avc\u0131","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sule","family":"Ketenci Ertas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mustafa","family":"Atasoy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2560","published-online":{"date-parts":[[2017,3,23]]},"reference":[{"key":"ref-1","first-page":"168-73","article-title":"Does familial occurrence or family history of recurrent oral ulcers 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Kemp","year":"2001","journal-title":"Autoimmunity."},{"key":"ref-5","doi-asserted-by":"publisher","first-page":"338-347","DOI":"10.1111\/jdv.12107","article-title":"The International Criteria for Beh\u00e7et\u2019s Disease (ICBD): a collaborative study of 27 countries on the sensitivity and specificity of the new criteria.","volume":"28","year":"2014","journal-title":"J Eur Acad Dermatol Venereol."},{"key":"ref-6","first-page":"S107-9","article-title":"Beh\u00e7et's syndrome is not associated with vitiligo.","volume":"26","author":"M Oran","year":"2008","journal-title":"Clin Exp Rheumatol."},{"key":"ref-7","doi-asserted-by":"publisher","first-page":"e653-5","DOI":"10.1111\/j.1365-2230.2009.03359.x","article-title":"Beh\u00e7et's disease and vitiligo in two brothers: coincidence or association?","volume":"34","author":"M Borlu","year":"2009","journal-title":"Clin Exp Dermatol."},{"key":"ref-8","doi-asserted-by":"publisher","first-page":"268-70","DOI":"10.2165\/00128071-200910040-00008","article-title":"Vitiligo koebnerized by beh\u00e7et disease genital ulceration.","volume":"10","author":"Y Karincaoglu","year":"2009","journal-title":"Am J Clin Dermatol."},{"key":"ref-9","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/387140","article-title":"Vitiligo in a Patient Treated with Interferon Alpha-2a for Beh\u00e7et's Disease.","volume":"2012","author":"E Guney","year":"2012","journal-title":"Case Rep Med."},{"key":"ref-10","doi-asserted-by":"publisher","first-page":"1002-8","DOI":"10.1136\/bjo.80.11.1002","article-title":"Melanoma specific Th1 cytotoxic T lymphocyte lines in Vogt-Koyanagi-Harada disease.","volume":"80","author":"K Norose","year":"1996","journal-title":"Br J Ophthalmol."},{"key":"ref-11","doi-asserted-by":"publisher","first-page":"723-6","DOI":"10.1016\/j.humimm.2010.04.007","article-title":"STAT4 polymorphism in a Chinese Han population with Vogt-Koyanagi-Harada syndrome and Beh\u00e7et's disease.","volume":"71","author":"K Hu","year":"2010","journal-title":"Hum Immunol."},{"key":"ref-12","first-page":"23-6","article-title":"Vitiligo'nun Tan\u0131 ve Ay\u0131r\u0131c\u0131 Tan\u0131s\u0131.","volume":"2","author":"E Aktas","year":"2009","journal-title":"Turkiye Klinikleri Journal of Dermatology Special Topics."}],"container-title":["F1000Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/f1000research.com\/articles\/6-310\/v1\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/f1000research.com\/articles\/6-310\/v1\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/f1000research.com\/articles\/6-310\/v1\/iparadigms","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,12,6]],"date-time":"2018-12-06T10:21:57Z","timestamp":1544091717000},"score":1,"resource":{"primary":{"URL":"https:\/\/f1000research.com\/articles\/6-310\/v1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3,23]]},"references-count":12,"URL":"https:\/\/doi.org\/10.12688\/f1000research.11025.1","relation":{"has-review":[{"id-type":"doi","id":"10.5256\/f1000research.11892.r22530","asserted-by":"subject"},{"id-type":"doi","id":"10.5256\/f1000research.11892.r21204","asserted-by":"subject"},{"id-type":"doi","id":"10.5256\/f1000research.11892.r22530","asserted-by":"object"},{"id-type":"doi","id":"10.5256\/f1000research.11892.r21204","asserted-by":"object"}]},"ISSN":["2046-1402"],"issn-type":[{"value":"2046-1402","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,3,23]]},"assertion":[{"value":"Indexed","URL":"https:\/\/f1000research.com\/articles\/6-310\/v1#article-reports","order":0,"name":"referee-status","label":"Referee 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grants were involved in supporting this work","order":2,"name":"grant-information","label":"Grant Information"},{"value":"This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.Data associated with the article are available under the terms of the Creative Commons Zero \"No rights reserved\" data waiver (CC0 1.0 Public domain dedication).","order":0,"name":"copyright-info","label":"Copyright"}]}}