{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T05:06:46Z","timestamp":1772168806424,"version":"3.50.1"},"reference-count":4,"publisher":"F1000 Research Ltd","license":[{"start":{"date-parts":[[2017,4,3]],"date-time":"2017-04-03T00:00:00Z","timestamp":1491177600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["f1000research.com"],"crossmark-restriction":false},"short-container-title":["F1000Res"],"abstract":"<ns4:p>Background: Ocular morbidity associated with systemic tuberculosis is common. The clinical picture varies from anterior uveitis, intermediate uveitis and posterior uveitis to even panuveitis. There is little data on the correlation between specific systemic presentations and the ocular inflammation. We conducted a retrospective review of the ocular findings in the case records of patients admitted with a diagnosis of miliary tuberculosis. These patients were then referred for a more detailed ophthalmic evaluation.<\/ns4:p>\n                  <ns4:p>Methods: We analysed the case records of patients with a clinical diagnosis of miliary tuberculosis over a 10-year period at Lilavati Hospital \u00a0and Research Center, Mumbai.<\/ns4:p>\n                  <ns4:p>Results: In total, 11 immunocompetent patients were identified. All 22 eyes showed normal findings on slit lamp examination. Dilated fundus examination showed single or multiple tubercles. In our cohort, the ocular findings were exclusively in the form of choroidal tuberculosis, either unilaterally or bilaterally. Slit lamp examination revealed no anterior segment inflammation<\/ns4:p>\n                  <ns4:p>Conclusions: We suggest that this pattern of choroidal\/retinal tuberculosis in the absence of anterior and intermediate segment inflammation is specific for miliary tuberculosis and may be related to a specific immune response.<\/ns4:p>","DOI":"10.12688\/f1000research.11035.1","type":"journal-article","created":{"date-parts":[[2017,4,3]],"date-time":"2017-04-03T10:00:18Z","timestamp":1491213618000},"page":"412","update-policy":"https:\/\/doi.org\/10.12688\/f1000research.crossmark-policy","source":"Crossref","is-referenced-by-count":6,"title":["Patterns of ocular inflammation in patients with miliary tuberculosis"],"prefix":"10.12688","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4175-459X","authenticated-orcid":false,"given":"Salil","family":"Mehta","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2560","published-online":{"date-parts":[[2017,4,3]]},"reference":[{"key":"ref-1","doi-asserted-by":"publisher","DOI":"10.5256\/f1000research.11035.d155310","article-title":"Dataset 1 in: Patterns of ocular inflammation in patients with miliary tuberculosis: An observational study.","author":"S Mehta","year":"2017","journal-title":"F1000Research."},{"key":"ref-2","doi-asserted-by":"publisher","first-page":"13-27","DOI":"10.1016\/j.jctube.2016.03.003","article-title":"Miliary tuberculosis: A new look at an old foe.","volume":"3","author":"S Sharma","year":"2016","journal-title":"J Clin Tuberc Other Mycobact Dis."},{"key":"ref-3","doi-asserted-by":"publisher","first-page":"415-30","DOI":"10.1016\/S1473-3099(05)70163-8","article-title":"Miliary tuberculosis: new insights into an old disease.","volume":"5","author":"S Sharma","year":"2005","journal-title":"Lancet Infect Dis."},{"key":"ref-4","doi-asserted-by":"publisher","first-page":"1-3","DOI":"10.1080\/09273948.2016.1194436","article-title":"Observed Patterns of Systemic Disease on PET\/CT Scan in Patients with Presumed Ocular Tuberculosis: Findings and Hypotheses.","author":"S Mehta","year":"2016","journal-title":"Ocul Immunol Inflamm."}],"container-title":["F1000Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/f1000research.com\/articles\/6-412\/v1\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/f1000research.com\/articles\/6-412\/v1\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/f1000research.com\/articles\/6-412\/v1\/iparadigms","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,12,6]],"date-time":"2018-12-06T10:18:19Z","timestamp":1544091499000},"score":1,"resource":{"primary":{"URL":"https:\/\/f1000research.com\/articles\/6-412\/v1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4,3]]},"references-count":4,"URL":"https:\/\/doi.org\/10.12688\/f1000research.11035.1","relation":{"has-review":[{"id-type":"doi","id":"10.5256\/f1000research.11903.r22605","asserted-by":"subject"},{"id-type":"doi","id":"10.5256\/f1000research.11903.r21512","asserted-by":"subject"},{"id-type":"doi","id":"10.5256\/f1000research.11903.r21905","asserted-by":"subject"},{"id-type":"doi","id":"10.5256\/f1000research.11903.r21514","asserted-by":"subject"},{"id-type":"doi","id":"10.5256\/f1000research.11903.r21905","asserted-by":"object"},{"id-type":"doi","id":"10.5256\/f1000research.11903.r21514","asserted-by":"object"},{"id-type":"doi","id":"10.5256\/f1000research.11903.r22605","asserted-by":"object"},{"id-type":"doi","id":"10.5256\/f1000research.11903.r21512","asserted-by":"object"}]},"ISSN":["2046-1402"],"issn-type":[{"value":"2046-1402","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,4,3]]},"assertion":[{"value":"Indexed","URL":"https:\/\/f1000research.com\/articles\/6-412\/v1#article-reports","order":0,"name":"referee-status","label":"Referee status","group":{"name":"current-referee-status","label":"Current Referee Status"}},{"value":"10.5256\/f1000research.11903.r21905, Jyotirmay Biswas, Vision Research Foundation, Sankara Nethralaya, Chennai, Tamil Nadu, India, 18 Apr 2017, version 1, indexed","URL":"https:\/\/f1000research.com\/articles\/6-412\/v1#referee-response-21905","order":0,"name":"referee-response-21905","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"10.5256\/f1000research.11903.r21512, Reema Bansal, Department of Ophthalmology, Advanced Eye Center, Postgraduate Institute of Medical Education and Research, Chandigarh, Haryana, Punjab, India, 21 Apr 2017, version 1, indexed","URL":"https:\/\/f1000research.com\/articles\/6-412\/v1#referee-response-21512","order":1,"name":"referee-response-21512","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"10.5256\/f1000research.11903.r22605, Somasheila I. Murthy, LV Prasad Eye Institute, Hyderabad, Telangana, India, 10 May 2017, version 1, indexed","URL":"https:\/\/f1000research.com\/articles\/6-412\/v1#referee-response-22605","order":2,"name":"referee-response-22605","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"10.5256\/f1000research.11903.r21514, Padmamalini Mahendradas, Department of Uveitis and Ocular Immunology, Narayana Nethralaya, Bengaluru, Karnataka, India, 11 May 2017, version 1, indexed","URL":"https:\/\/f1000research.com\/articles\/6-412\/v1#referee-response-21514","order":3,"name":"referee-response-21514","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"The author(s) declared that no grants were involved in supporting this work","order":4,"name":"grant-information","label":"Grant Information"},{"value":"This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.Data associated with the article are available under the terms of the Creative Commons Zero \"No rights reserved\" data waiver (CC0 1.0 Public domain dedication).","order":0,"name":"copyright-info","label":"Copyright"}]}}