{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T05:07:49Z","timestamp":1772168869234,"version":"3.50.1"},"update-to":[{"DOI":"10.12688\/f1000research.12327.1","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2017,12,22]],"date-time":"2017-12-22T00:00:00Z","timestamp":1513900800000}}],"reference-count":10,"publisher":"F1000 Research Ltd","license":[{"start":{"date-parts":[[2017,12,22]],"date-time":"2017-12-22T00:00:00Z","timestamp":1513900800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","award":["K24 MH087913"],"award-info":[{"award-number":["K24 MH087913"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","award":["R01 MH104030"],"award-info":[{"award-number":["R01 MH104030"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","award":["R21 NS091635"],"award-info":[{"award-number":["R21 NS091635"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["f1000research.com"],"crossmark-restriction":false},"short-container-title":["F1000Res"],"abstract":"<ns4:p>Woods and Himle developed a standardized tic suppression paradigm (TSP) for the experimental setting, to quantify the effects of intentional tic suppression in Tourette syndrome. The present article describes a Java program that automates record keeping and reward dispensing during the several experimental conditions of the TSP. The software can optionally be connected to a commercial reward token dispenser to further automate reward delivery to the participant. The timing of all tics, 10-second tic-free intervals, and dispensed rewards is recorded in plain text files for later analysis. Expected applications include research on Tourette syndrome and related disorders.<\/ns4:p>","DOI":"10.12688\/f1000research.12327.2","type":"journal-article","created":{"date-parts":[[2017,12,22]],"date-time":"2017-12-22T10:20:52Z","timestamp":1513938052000},"page":"1560","update-policy":"https:\/\/doi.org\/10.12688\/f1000research.crossmark-policy","source":"Crossref","is-referenced-by-count":5,"title":["TicTimer software for measuring tic suppression"],"prefix":"10.12688","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9324-915X","authenticated-orcid":false,"given":"Jonathan K.","family":"Black","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1409-5608","authenticated-orcid":false,"given":"Jonathan M.","family":"Koller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6921-9567","authenticated-orcid":false,"given":"Kevin J.","family":"Black","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2560","published-online":{"date-parts":[[2017,12,22]]},"reference":[{"key":"ref-1","doi-asserted-by":"crossref","first-page":"417-20","DOI":"10.1901\/jaba.2004.37-417","article-title":"Creating tic suppression: comparing the effects of verbal instruction to differential reinforcement.","volume":"37","author":"D Woods","year":"2004","journal-title":"J Appl Behav Anal."},{"key":"ref-2","doi-asserted-by":"publisher","first-page":"1443-51","DOI":"10.1016\/j.brat.2004.11.002","article-title":"An experimental evaluation of tic suppression and the tic rebound effect.","volume":"43","author":"M Himle","year":"2005","journal-title":"Behav Res Ther."},{"key":"ref-3","doi-asserted-by":"crossref","first-page":"285-9","DOI":"10.1901\/jaba.2008.41-285","article-title":"Evaluating the role of contingency in differentially reinforced tic suppression.","volume":"41","author":"M Himle","year":"2008","journal-title":"J Appl Behav Anal."},{"key":"ref-4","doi-asserted-by":"publisher","first-page":"283-9","DOI":"10.1089\/cap.2010.0032","article-title":"Testing tic suppression: comparing the effects of dexmethylphenidate to no medication in children and adolescents with attention-deficit\/hyperactivity disorder and Tourette\u2019s disorder.","volume":"20","author":"G Lyon","year":"2010","journal-title":"J Child Adolesc Psychopharmacol."},{"key":"ref-5","doi-asserted-by":"publisher","first-page":"204933","DOI":"10.1101\/204933","article-title":"Patterns and predictors of tic suppressibility in youth with tic disorders.","author":"C Conelea","year":"2017","journal-title":"bioRxiv."},{"key":"ref-6","doi-asserted-by":"publisher","first-page":"696","DOI":"10.12688\/f1000research.8428.1","article-title":"Provisional Tic Disorder: What to tell parents when their child first starts ticcing [version 1; referees: 3 approved].","volume":"5","author":"K Black","year":"2016","journal-title":"F1000Res."},{"key":"ref-7","doi-asserted-by":"publisher","first-page":"65-74","DOI":"10.1016\/j.dcn.2014.08.005","article-title":"Reward enhances tic suppression in children within months of tic disorder onset.","volume":"11","author":"D Greene","year":"2015","journal-title":"Dev Cogn Neurosci."},{"key":"ref-8","doi-asserted-by":"publisher","article-title":"Obsessive-Compulsive and Related Disorders","year":"2013","DOI":"10.1176\/appi.books.9780890425596.dsm06"},{"key":"ref-9","doi-asserted-by":"publisher","DOI":"10.22541\/au.150161712.22184874","article-title":"TicTimer software for measuring tic suppression","author":"J Black","year":"2017"},{"key":"ref-10","doi-asserted-by":"publisher","first-page":"2150","DOI":"10.12688\/f1000research.13460.1","article-title":"Software for web-based tic suppression training [version 1; referees: awaiting peer review].","volume":"6","author":"J Black","year":"2017","journal-title":"F1000Res."}],"container-title":["F1000Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/f1000research.com\/articles\/6-1560\/v2\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/f1000research.com\/articles\/6-1560\/v2\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/f1000research.com\/articles\/6-1560\/v2\/iparadigms","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,12,6]],"date-time":"2018-12-06T07:09:58Z","timestamp":1544080198000},"score":1,"resource":{"primary":{"URL":"https:\/\/f1000research.com\/articles\/6-1560\/v2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12,22]]},"references-count":10,"URL":"https:\/\/doi.org\/10.12688\/f1000research.12327.2","relation":{"has-review":[{"id-type":"doi","id":"10.5256\/f1000research.14702.r29268","asserted-by":"subject"},{"id-type":"doi","id":"10.5256\/f1000research.14702.r29268","asserted-by":"object"}]},"ISSN":["2046-1402"],"issn-type":[{"value":"2046-1402","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,12,22]]},"assertion":[{"value":"Indexed","URL":"https:\/\/f1000research.com\/articles\/6-1560\/v2#article-reports","order":0,"name":"referee-status","label":"Referee status","group":{"name":"current-referee-status","label":"Current Referee Status"}},{"value":"10.5256\/f1000research.14702.r29268, Danielle C. Cath, Department of Psychiatry, University Medical Centre Groningen, Groningen, The Netherlands, 12 Jan 2018, version 2, indexed","URL":"https:\/\/f1000research.com\/articles\/6-1560\/v2#referee-response-29268","order":0,"name":"referee-response-29268","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"10.5256\/f1000research.13345.r26009, Patrick Haggard, Institute of Cognitive Neuroscience & Department of Psychology, University College London, London, WC1N 3AR, UK, 06 Nov 2017, version 1, 1 approved, 1 approved with reservations","URL":"https:\/\/f1000research.com\/articles\/6-1560\/v1#referee-response-26009","order":1,"name":"referee-response-26009","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"<b>Kevin J Black<\/b>; \n<i>Posted: 16 Dec 2017<\/i>; We are grateful for the careful attention and thoughtful suggestions of Prof. Haggard. Here we reply to each point in his review of version 1.  \n<i>The software doesn't detect tics automatically; the accuracy of any rater-identified tics depend on the skill of the rater.<\/i>&nbsp;These points are all valid. The scope of the software is limited, primarily being useful to track and time the tics as noted by an expert observer, who indeed logs each tic by pressing a keyboard button or clicking a mouse. We have updated the text to clarify these details. \n<i>&quot;The user seems to have to write their own scripts to produce synthetic reports.&quot;<\/i>&nbsp;We do supply (via GitHub) the python script TT_Data.py for summarizing each primary data file, but apparently we failed to provide a direct link to this script. We have corrected this omission in this revision. \n<i>The choice of 10 seconds as the tic-free interval of interest is arbitrary.<\/i>&nbsp;We chose the 10s period because of its prior use in the studies cited, but you\u2019re correct that this choice is otherwise arbitrary. We have explained this choice in the revised ms. The suggestions in (b) are interesting, but to some extent outside of our plan for the software. We have modified the source code, however, to make a change in tic-free intervals easier to make at compile time. \n<i>&quot;The strength of the tool seems to be the automation of reward scheduling for studies of voluntary tic suppression in children.<\/i>\n<i>&quot;<\/i>&nbsp;Yes, we also see that as one of its key advantages. We&nbsp;expect TicTimer&nbsp;could be applied equally well to studies of adults.","URL":"https:\/\/f1000research.com\/articles\/6-1560\/v2#referee-comment-3279","order":2,"name":"referee-comment-3279","label":"Referee Comment","group":{"name":"article-reports","label":"Article Reports"}},{"value":"Software development and manuscript preparation were funded in part by the U.S. National Institutes of Health (NIH), grant numbers K24 MH087913, R21 NS091635, and R01 MH104030. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.","order":3,"name":"grant-information","label":"Grant Information"},{"value":"This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.Data associated with the article are available under the terms of the Creative Commons Zero \"No rights reserved\" data waiver (CC0 1.0 Public domain dedication).","order":0,"name":"copyright-info","label":"Copyright"}]}}