{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T05:06:23Z","timestamp":1772168783611,"version":"3.50.1"},"reference-count":37,"publisher":"F1000 Research Ltd","license":[{"start":{"date-parts":[[2017,10,4]],"date-time":"2017-10-04T00:00:00Z","timestamp":1507075200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["f1000research.com"],"crossmark-restriction":false},"short-container-title":["F1000Res"],"abstract":"<ns4:p>Herein we report the management of a giant, high-grade and vascular carotid body tumor in a young woman. She presented with slowly progressive neck swelling. Vascular imaging revealed a left-sided, high-grade giant carotid body tumor (&gt; 8cm).\u00a0 The tumor was completely excised by caudocranial subadventitial dissection. Histology of the tumor revealed a characteristic Zellballen pattern of the lesion, suggestive of a paraganglioma. The patient made an uneventful recovery. We also discuss newer insights regarding the management of such highly vascular lesions.<\/ns4:p>","DOI":"10.12688\/f1000research.12726.1","type":"journal-article","created":{"date-parts":[[2017,10,4]],"date-time":"2017-10-04T07:25:15Z","timestamp":1507101915000},"page":"1801","update-policy":"https:\/\/doi.org\/10.12688\/f1000research.crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Case Report: Managing a giant, high-grade carotid body tumor in a resource-limited setting"],"prefix":"10.12688","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6079-3792","authenticated-orcid":false,"given":"Sunil","family":"Munakomi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samrita","family":"Chaudhary","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1750-7740","authenticated-orcid":false,"given":"Iype","family":"Cherian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2560","published-online":{"date-parts":[[2017,10,4]]},"reference":[{"key":"ref-1","doi-asserted-by":"publisher","first-page":"1462-1464","DOI":"10.1016\/j.jvs.2013.10.075","article-title":"A simple technique to achieve bloodless excision of carotid body tumors.","volume":"59","author":"F Spinelli","year":"2014","journal-title":"J Vasc Surg."},{"key":"ref-2","doi-asserted-by":"publisher","first-page":"958-964","DOI":"10.1016\/j.jvs.2015.05.001","article-title":"Comparison of retrocarotid and caudocranial dissection techniques for the surgical treatment of carotid body tumors.","volume":"62","author":"C Hinojosa","year":"2015","journal-title":"J Vasc Surg."},{"key":"ref-3","first-page":"117-186","article-title":"Carotid tumors: A collective review.","volume":"7","author":"Von Haller","year":"1943","journal-title":"Abstr Surg."},{"key":"ref-4","first-page":"e58-e60","article-title":"Carotid body tumours: three case reports.","volume":"50","author":"B Mathew","year":"2009","journal-title":"Singapore Med J."},{"key":"ref-5","doi-asserted-by":"publisher","first-page":"86-88","DOI":"10.4103\/1995-705X.144800","article-title":"Assessment of carotid body tumor and its association with tetralogy of fallot: effect of the chronic hypoxia.","volume":"15","author":"B Yildiz","year":"2014","journal-title":"Heart Views."},{"key":"ref-6","doi-asserted-by":"publisher","first-page":"526-528","DOI":"10.1016\/0002-9610(83)90052-1","article-title":"Carotid body tumor: The Lahey Clinic experience.","volume":"145","author":"F Padberg","year":"1983","journal-title":"Am J Surg."},{"key":"ref-7","doi-asserted-by":"publisher","first-page":"806-808","DOI":"10.1111\/j.1365-2044.1979.tb06414.x","article-title":"Anesthesia for carotid body tumour resection.","volume":"34","author":"D Wright","year":"1979","journal-title":"Anaesthesia."},{"key":"ref-8","doi-asserted-by":"publisher","first-page":"104-10","DOI":"10.1016\/j.amjsurg.2005.10.010","article-title":"Current concepts for the surgical management of carotid body tumor.","volume":"191","author":"T Knight","year":"2006","journal-title":"Am J Surg."},{"key":"ref-9","doi-asserted-by":"publisher","first-page":"E606","DOI":"10.1503\/cmaj.092114","article-title":"Bilateral carotid body paragangliomas.","volume":"183","author":"S Wang","year":"2011","journal-title":"CMAJ."},{"key":"ref-10","first-page":"129-133","article-title":"Role of duplex ultrasound in the diagnosis and assessment of carotid body tumour: A literature review.","volume":"1","author":"Y Tong","year":"2012","journal-title":"Intractable Rare Dis Res."},{"key":"ref-11","doi-asserted-by":"publisher","first-page":"732-39","DOI":"10.1016\/0002-9610(71)90436-3","article-title":"Carotid body tumor (chemodectoma). 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article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.","order":0,"name":"copyright-info","label":"Copyright"}]}}