{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T05:08:07Z","timestamp":1772168887001,"version":"3.50.1"},"update-to":[{"DOI":"10.12688\/f1000research.13295.1","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2018,4,16]],"date-time":"2018-04-16T00:00:00Z","timestamp":1523836800000}}],"reference-count":19,"publisher":"F1000 Research Ltd","license":[{"start":{"date-parts":[[2018,4,16]],"date-time":"2018-04-16T00:00:00Z","timestamp":1523836800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["f1000research.com"],"crossmark-restriction":false},"short-container-title":["F1000Res"],"abstract":"<ns4:p>\n                    <ns4:bold>Background<\/ns4:bold>\n                    : Polyarteritis nodosa (PAN) is a vasculitis that affects medium-sized arteries. PAN is a rare disease and requires a high clinical suspicion for diagnosis. PAN and HSP (newly named Immunoglobulin A-associated vasculitis) have narrowing differential diagnosis. Here, we reported a case of PAN.\n                  <\/ns4:p>\n                  <ns4:p>\n                    <ns4:bold>Case presentation<\/ns4:bold>\n                    : Our patient was a 65-year-old woman that came to hospital due to abdominal pain and skin lesion on the right upper and right lower extremities. All rheumatologic tests were negative. A biopsy of the skin lesion was reported as mild hyperkeratosis, slight spongiosis with intact basal layer. The dermis showed moderate to severe perivascular PMN infiltration with vessel wall degeneration and extravasation of RBCs. A colonoscopy reported diffuse mucosal erythema and erosions were seen in the rectum until 6cm of anal verge. An electromyogram test and nerve conduction velocity study of the upper extremities reported bilateral mild carpal tunnel syndrome, and in the right lower extremities mononeuritis multiplex could not be ruled out. Abdominopelvic CT scan reported diffuse wall thickening of terminal ileum associated with mesenteric fat and narrow enhancement of inferior Mesenteric artery with patchy filling defect. After evaluation, the patient received corticosteroid pulses plus cyclophosphamide.\n                  <\/ns4:p>\n                  <ns4:p>\n                    <ns4:bold>Conclusion<\/ns4:bold>\n                    : Diagnosis and treatment of PAN are important and PAN should be considered in a patient with skin lesions and neurological impairment.\n                  <\/ns4:p>","DOI":"10.12688\/f1000research.13295.2","type":"journal-article","created":{"date-parts":[[2018,4,16]],"date-time":"2018-04-16T11:35:10Z","timestamp":1523878510000},"page":"49","update-policy":"https:\/\/doi.org\/10.12688\/f1000research.crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Case Report: Polyarteritis nodosa or complicated Henoch-Schonlein purpura (IgAV), a rare case"],"prefix":"10.12688","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6747-0750","authenticated-orcid":false,"given":"Sajad","family":"Hasanzadeh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seyedeh Maryam","family":"Alavi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0187-5736","authenticated-orcid":false,"given":"Elahe","family":"Masnavi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5056-9092","authenticated-orcid":false,"given":"Saeid","family":"Jokar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maryam","family":"Rohani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2560","published-online":{"date-parts":[[2018,4,16]]},"reference":[{"key":"ref-1","article-title":"Polyarteritis and microscopic polyangiitis.","author":"O Sato","year":"2003"},{"key":"ref-2","doi-asserted-by":"publisher","first-page":"92-9","DOI":"10.1002\/art.20077","article-title":"Prevalences of polyarteritis nodosa, microscopic polyangiitis, Wegener's granulomatosis, and Churg-Strauss syndrome in a French urban multiethnic population in 2000: a capture-recapture estimate.","volume":"51","author":"A Mahr","year":"2004","journal-title":"Arthritis Rheum."},{"key":"ref-3","doi-asserted-by":"publisher","first-page":"1442-8","DOI":"10.3899\/jrheum.080874","article-title":"Systemic autoimmune diseases in patients with hepatitis C virus infection: characterization of 1020 cases (The HISPAMEC Registry).","volume":"36","author":"M Ramos-Casals","year":"2009","journal-title":"J Rheumatol."},{"key":"ref-4","doi-asserted-by":"publisher","first-page":"313-22","DOI":"10.1097\/01.md.0000180792.80212.5e","article-title":"Hepatitis B virus-associated polyarteritis nodosa: clinical characteristics, outcome, and impact of treatment in 115 patients.","volume":"84","author":"L Guillevin","year":"2005","journal-title":"Medicine (Baltimore)."},{"key":"ref-5","doi-asserted-by":"publisher","first-page":"517-22","DOI":"10.1016\/j.jpeds.2004.06.046","article-title":"Juvenile polyarteritis: results of a multicenter survey of 110 children.","volume":"145","author":"S Ozen","year":"2004","journal-title":"J Pediatr."},{"key":"ref-6","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1186\/s13075-016-0959-4","article-title":"IgA vasculitis in adults: the performance of the EULAR\/PRINTO\/PRES classification criteria in adults.","volume":"18","author":"A Ho\u010devar","year":"2016","journal-title":"Arthritis Res Ther."},{"key":"ref-7","doi-asserted-by":"publisher","first-page":"1-15","DOI":"10.1038\/ki.1994.239","article-title":"Anti-neutrophil cytoplasmic antibodies: current diagnostic and pathophysiological potential.","volume":"46","author":"C Kallenberg","year":"1994","journal-title":"Kidney 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Gardner-Medwin","year":"2002","journal-title":"Lancet."},{"key":"ref-18","doi-asserted-by":"publisher","first-page":"1151-7","DOI":"10.4065\/79.9.1151","article-title":"Pulmonary involvement in Henoch-Sch\u00f6nlein purpura.","volume":"79","author":"H Nadrous","year":"2004","journal-title":"Mayo Clin Proc."},{"key":"ref-19","doi-asserted-by":"publisher","first-page":"798-806","DOI":"10.1136\/ard.2009.116657","article-title":"EULAR\/PRINTO\/PRES criteria for Henoch-Sch\u00f6nlein purpura, childhood polyarteritis nodosa, childhood Wegener granulomatosis and childhood Takayasu arteritis: Ankara 2008. Part II: Final classification criteria.","volume":"69","author":"S Ozen","year":"2010","journal-title":"Ann Rheum Dis."}],"container-title":["F1000Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/f1000research.com\/articles\/7-49\/v2\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/f1000research.com\/articles\/7-49\/v2\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/f1000research.com\/articles\/7-49\/v2\/iparadigms","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,19]],"date-time":"2022-08-19T15:59:47Z","timestamp":1660924787000},"score":1,"resource":{"primary":{"URL":"https:\/\/f1000research.com\/articles\/7-49\/v2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4,16]]},"references-count":19,"URL":"https:\/\/doi.org\/10.12688\/f1000research.13295.2","relation":{"has-review":[{"id-type":"doi","id":"10.5256\/f1000research.15802.r33221","asserted-by":"subject"},{"id-type":"doi","id":"10.5256\/f1000research.15802.r33220","asserted-by":"subject"},{"id-type":"doi","id":"10.5256\/f1000research.15802.r33221","asserted-by":"object"},{"id-type":"doi","id":"10.5256\/f1000research.15802.r33220","asserted-by":"object"}]},"ISSN":["2046-1402"],"issn-type":[{"value":"2046-1402","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,4,16]]},"assertion":[{"value":"Indexed","URL":"https:\/\/f1000research.com\/articles\/7-49\/v2#article-reports","order":0,"name":"referee-status","label":"Referee status","group":{"name":"current-referee-status","label":"Current Referee Status"}},{"value":"10.5256\/f1000research.15802.r33220, Marco de Vincentiis, Department of Oral and Maxillofacial Sciences, Sapienza University of Rome, Rome, Italy, 17 Apr 2018, version 2, indexed","URL":"https:\/\/f1000research.com\/articles\/7-49\/v2#referee-response-33220","order":0,"name":"referee-response-33220","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"10.5256\/f1000research.15802.r33221, Patricia Woo, Division of Infection and Immunity, University College London, London, UK, 01 May 2018, version 2, indexed","URL":"https:\/\/f1000research.com\/articles\/7-49\/v2#referee-response-33221","order":1,"name":"referee-response-33221","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"The author(s) declared that no grants were involved in supporting this work","order":2,"name":"grant-information","label":"Grant Information"},{"value":"This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.Data associated with the article are available under the terms of the Creative Commons Zero \"No rights reserved\" data waiver (CC0 1.0 Public domain dedication).","order":0,"name":"copyright-info","label":"Copyright"}]}}