{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T10:26:15Z","timestamp":1780050375198,"version":"3.53.1"},"update-to":[{"DOI":"10.12688\/f1000research.14032.1","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2018,8,10]],"date-time":"2018-08-10T00:00:00Z","timestamp":1533859200000}}],"reference-count":79,"publisher":"F1000 Research Ltd","license":[{"start":{"date-parts":[[2018,8,10]],"date-time":"2018-08-10T00:00:00Z","timestamp":1533859200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"International Centre of Insect Physiology and Ecology, Nairobi, Kenya"}],"content-domain":{"domain":["f1000research.com"],"crossmark-restriction":false},"short-container-title":["F1000Res"],"abstract":"<ns4:p>\n                    <ns4:bold>Background:<\/ns4:bold>\n                    Animal trypanosomosis is a major cause of economic loss in livestock production in Africa. A suggested control measure is to use breeds with traits of trypanotolerance. The study examines the effect of natural\n                    <ns4:italic>Trypanosoma vivax<\/ns4:italic>\n                    challenge on haematological parameters in two trypanotolerant cattle [N\u2019Dama and West African Shorthorn (WASH)] herds.\n                  <\/ns4:p>\n                  <ns4:p>\n                    <ns4:bold>Methods:<\/ns4:bold>\n                    <ns4:italic>Trypanosoma vivax<\/ns4:italic>\n                    -specific primers were used to diagnose\n                    <ns4:italic>T. vivax<\/ns4:italic>\n                    infection in an N\u2019Dama herd at Cape Coast in southern Ghana and a WASH herd at Chegbani in northern Ghana from May to July 2011 in a cross-sectional study. Levels of haematological parameters comprising packed cell volume (PCV), haemoglobin (Hb) concentration and red blood cell (RBC) and total white blood cell (TWBC) counts; differential WBC counts (neutrophils, lymphocytes, eosinophils, monocytes and basophils); and RBC indices of mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH) and mean corpuscular haemoglobin concentration (MCHC) were determined in blood samples and then compared between infected and uninfected cattle.\n                  <\/ns4:p>\n                  <ns4:p>\n                    <ns4:bold>Results:<\/ns4:bold>\n                    We found that haematological indices for infected and uninfected animals in both breeds were within the normal range. However, the mean PCV values for\n                    <ns4:italic>T. vivax<\/ns4:italic>\n                    -infected WASH and N\u2019Dama were lower in infected compared to uninfected animals. The difference was significant (\n                    <ns4:italic>p<\/ns4:italic>\n                    &lt; 0.05) in N\u2019Dama but not in WASH.\n                  <\/ns4:p>\n                  <ns4:p>\n                    <ns4:bold>Conclusion:<\/ns4:bold>\n                    Despite the presence of infection by\n                    <ns4:italic>T. vivax<\/ns4:italic>\n                    , N\u2019Dama and WASH cattle maintained their haematological parameters within acceptable normal ranges, \u00a0which confirms their trypanotolerant trait. This highlights the need for low-input traditional African farmers in medium, high and severe tsetse challenge areas to be educated on the advantages of N\u2019Dama and WASH breeds to increase their utilization in integrated tsetse and trypanosomosis control programmes.\n                  <\/ns4:p>","DOI":"10.12688\/f1000research.14032.2","type":"journal-article","created":{"date-parts":[[2018,8,10]],"date-time":"2018-08-10T05:05:09Z","timestamp":1533877509000},"page":"314","update-policy":"https:\/\/doi.org\/10.12688\/f1000research.crossmark-policy","source":"Crossref","is-referenced-by-count":7,"title":["Haematology of N\u2019Dama and West African Shorthorn cattle herds under natural Trypanosoma vivax challenge in Ghana"],"prefix":"10.12688","volume":"7","author":[{"given":"Ebenezer Yaw","family":"Ganyo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johnson N","family":"Boampong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7513-0887","authenticated-orcid":false,"given":"Daniel K","family":"Masiga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jandouwe","family":"Villinger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5319-2021","authenticated-orcid":false,"given":"Paa Kobina","family":"Turkson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2560","published-online":{"date-parts":[[2018,8,10]]},"reference":[{"key":"ref-1","first-page":"807-814","article-title":"Trypanosomosis in the Doayo\/Namchi (Bos taurus and zebu White Fulani (Bos indicus) cattle in Faro Division, North Cameroon.","volume":"15","author":"M Achukwi","year":"2009","journal-title":"J 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Parasitol."}],"container-title":["F1000Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/f1000research.com\/articles\/7-314\/v2\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/f1000research.com\/articles\/7-314\/v2\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/f1000research.com\/articles\/7-314\/v2\/iparadigms","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,12,6]],"date-time":"2018-12-06T15:32:56Z","timestamp":1544110376000},"score":1,"resource":{"primary":{"URL":"https:\/\/f1000research.com\/articles\/7-314\/v2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8,10]]},"references-count":79,"URL":"https:\/\/doi.org\/10.12688\/f1000research.14032.2","relation":{"has-review":[{"id-type":"doi","id":"10.5256\/f1000research.17131.r36986","asserted-by":"subject"},{"id-type":"doi","id":"10.5256\/f1000research.17131.r36985","asserted-by":"subject"},{"id-type":"doi","id":"10.5256\/f1000research.17131.r36986","asserted-by":"object"},{"id-type":"doi","id":"10.5256\/f1000research.17131.r36985","asserted-by":"object"}]},"ISSN":["2046-1402"],"issn-type":[{"value":"2046-1402","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,8,10]]},"assertion":[{"value":"Indexed","URL":"https:\/\/f1000research.com\/articles\/7-314\/v2#article-reports","order":0,"name":"referee-status","label":"Referee status","group":{"name":"current-referee-status","label":"Current Referee Status"}},{"value":"10.5256\/f1000research.15253.r33102, Yahaya Adam, Tsetse and Trypanosomiasis Control Unit\/PATTEC, Ministry of Food and Agriculture, Pong-Tamale, Ghana, 25 Apr 2018, version 1, 1 approved, 1 approved with reservations, 1 not approved","URL":"https:\/\/f1000research.com\/articles\/7-314\/v1#referee-response-33102","order":0,"name":"referee-response-33102","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"<b>Paa Kobina<\/b>; \n<i>Posted: 25 Apr 2018<\/i>; We accept the comments of the Referee. We agree that the two breeds are not as productive as other breeds but having them deal better with trypanosomosis is considered by some livestock keepers as an advantage to keep them and therefore may be preferred..","URL":"https:\/\/f1000research.com\/articles\/7-314\/v2#referee-comment-3618","order":1,"name":"referee-comment-3618","label":"Referee Comment","group":{"name":"article-reports","label":"Article Reports"}},{"value":"10.5256\/f1000research.17131.r36986, David M Groth, School\u00a0of\u00a0Biomedical Sciences, Curtin University, Bentley, WA, Australia, 26 Sep 2018, version 2, indexed","URL":"https:\/\/f1000research.com\/articles\/7-314\/v2#referee-response-36986","order":2,"name":"referee-response-36986","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"10.5256\/f1000research.17131.r36985, Sophie Th\u00e9venon, UMR INTERTRYP, French Agricultural Research Centre for International Development (CIRAD)\u00a0, Montpellier, France, 29 Aug 2018, version 2, indexed","URL":"https:\/\/f1000research.com\/articles\/7-314\/v2#referee-response-36985","order":3,"name":"referee-response-36985","label":"Referee Report","group":{"name":"article-reports","label":"Article Reports"}},{"value":"This work was supported in part by an International Centre of Insect Physiology and Ecology (icipe) six-month Dissertation Research Internship Programme (DRIP) fellowship funded by the Swedish International Development Cooperation Agency (Sida); and institutional financial support from UK Aid from the UK Government; the Swiss Agency for Development and Cooperation (SDC); and the Kenyan Government. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.","order":4,"name":"grant-information","label":"Grant Information"},{"value":"This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.Data associated with the article are available under the terms of the Creative Commons Zero \"No rights reserved\" data waiver (CC0 1.0 Public domain dedication).","order":0,"name":"copyright-info","label":"Copyright"}]}}